Brett M. Knappe, Ph.D. Email and Phone Number

Transition time after Medtronic before beginning new role.

• Led a complex cross-functional effort to design and implement the first ever Global Regions organization at Medtronic, spanning all commercial markets outside of China – resulting in a $5 billion global business with double-digit growth• Drove more than $125 million of cost savings and productivity gains while accelerating growth and delivering strong, consistent quarterly performance• Created and currently lead team of ~20 subject matter experts who coordinate strategic planning, business development, market insights, and transformation initiatives

• Created, staffed, and led the Office of the CEO, providing direct support and counsel to Medtronic’s chief executive and the members of its executive committee• Designed, implemented, and led strategic planning, capital allocation, portfolio management, and quarterly business review processes for the company• Prepared and delivered detailed analyses for the board and the executive committee • Led high-profile strategic initiatives related to digital health, China localization, centralization of equipment service and repair, and other enterprise priorities

• Hand-picked to lead a comprehensive transformation of Medtronic’s Operating Model• Worked closely with the C-suite and executive committee to set the strategy for the new Op Model; led a team of hundreds through microdesign and implementation• Drove $450 million of cost savings through restructuring and optimization of spans and layers; cost savings were then reinvested in top-priority growth initiatives• Launched a new brand and culture/mindset for the company• Achieved strong financial results and employee engagement following implementation • Received the Medtronic Chairman’s Award in recognition of this work

• Turned around the performance of MDT’s ~$1 billion global biologics business• Transformed product strategy (via organic and inorganic actions) and commercial model to drive growth; restructured business to improve performance and expand margins• Executed clinical trials for indication expansion and market access (e.g., Korea, China)• Exceeded 100% of revenue and profitability targets during tenure as GM

• Researched and implemented a new strategic vision for the Spine business unit, focused on the use of robotics and digital ecosystems to create a sustained competitive advantage• Executed numerous investments, licensing deals, and M&A initiatives to accelerate revenue growth (e.g., closed a data monetization deal, generating $5M of R&D funding)

• Served as the frontline leader for the integration of Covidien, the largest acquisition in medical device history. Delivered >$1 billion of cost synergies, while exceeding targets for business performance and talent retention• Led the creation of Medtronic’s Enterprise Excellence strategy; built a team of internal consultants and project managers for process improvement and ongoing cost out actions

• Planned and implemented a new US region organizational structure for the enterprise; developed value-based healthcare strategy and a new customer segmentation approach• Negotiated and closed $200M acquisition of private remote patient monitoring company

• Led all M&A, partnership, and licensing activity for the company in North America; within first six months, launched a global strategic alliance to support GPS agricultural products

P&L responsibility for $50M business, manufacturing and selling dental implants and related training services

Strategic planning, M&A pipeline development and execution for billion-dollar dental business

Multiple projects for clients in the health care, pharmaceutical, and financial services industries

Technical consulting for internal and external clients on topics related to polymer manufacturing