Brian Cheung, Phd Email & Phone Number

Seattle, Washington, United States

• Studied how innate immunity shapes T cell responses in non-small cell lung cancer (NSCLC) using mouse models• Investigated how neutrophil extracellular traps (NETs) influence T cell trafficking• Designed and fabricated microfluidic devices for in vitro functional assays• Designed and optimized high-dimensional flow cytometry panels for immune profiling

Ithaca, New York, United States

• Designed and performed in vitro assays to evaluate the effect of hyaluronic acid on NK cell-based immunotherapy and checkpoint inhibition• Designed multicolor flow cytometry panels to evaluate the effect of hyaluronic acid on immune cell cytotoxicity• Characterized and tested synthetic hydrogels mechanically to study NK immunogenicity• Designed a machine learning-assisted FRET imaging workflow to visualize molecular interactions in real-time• Designed optimization approaches to compute cell-induced hydrogel deformation and its associated forces• Genetically engineered NK cells to study the role of epithelial-to-mesenchymal transition in immunotherapy• Discovered the mechanobiological role of CD44 in force generation in the breast tumor microenvironment• Led and engaged in multiple collaborative research projects simultaneously• Mentored and trained junior graduate and undergraduate researchers to develop and perform independent research projects• Presented scientific findings in multiple national and institutional-level conferences

Ithaca, New York

• Investigated the spatial and temporal dynamics of RhoA in breast cancer cells in 2D and 3D.• Developed a robust image analysis workflow involving machine learning algorithms.• Designed and conducted senior undergraduate level project-based classes.• Conducted statistical analyses on experimental data using self-written programmes.• Presented at multiple national scientific conferences to establish new collaborations across universities in the US.• Mentored and trained undergraduate researchers to carry out data analysis projects.

Hong Kong Sar

• Studied the oncogenic effect of ARHGAP-CLDN18 fusion in gastric cancer from clinical samples• Designed and established protocols for visualizing molecular activities in tumor organoids• Performed molecular and functional assays to characterize tumor organoids

Hong Kong Sar

• Cooperated with development team to deliver the first local vaccination appointment system in Hong Kong.• Established partnerships with local clinics to deliver COVID-19 vaccinations to the public

Hong Kong

• Led, initiated, and executed process automation, resulting in over 50% increase of operational efficiency.• Solved operational bottlenecks, unlocking over 60% growth in sales and 3-fold increase in user registration in 3 months.• Analyzed marketplace behaviors from big data and built data dashboards for business development team.• Key driver in data-driven decision making through data pipeline design and SaaS integrations.

Hong Kong Sar

• Studied the protein-protein interactions in Arabidopsis thaliana involving E3 ligases and ubiquitin• Investigated the potential downstream regulatory proteins for various phenotypic changes in Arabidopsis using immunoprecipitation techniques

Hong Kong

• Studied the effect of Intermittent-Vibration (IV) on pressure ulcers (PrUs) formation in vivo and the age-related apoptotic signaling in PrUs formation• Handled and harvested in vivo samples for downstream analysis• Performed real-time PCR, immunohistochemical analysis, and immunoassays (ELISA) on in vivo samples to assess muscle damage

Hong Kong

• Implemented quantitative research on over 300 listed company in Hong Kong.• Re-designed the filing workflow which increased filing efficiency by 4-folds.

Hong Kong Sar

• Established over 20 partnerships with local enterprises to create professional internship opportunities for overseas graduates.• Collaborated with corporate partners to generate corporate social responsibility opportunities.• Renovated the pre-sales workflow by integrating project and data management systems.• Conducted training for new data management systems to establish consistency across the department.• Mentored and led a team of junior officers ensuring adequate product knowledge and quality standards in sales and product delivery.

Stony Brook, Ny, United States

• Investigated the biomechanical effect of Low-Intensity Vibrations (LIV) on a diet-induced obese mouse model, and a chronic heavy alcohol-consumption (CHAC) rat model• Evaluated the biomechanical properties of bones using 4-point bending, nanoindentation and bioimaging techniques

Doctor Of Philosophy - Phd, Biological Engineering

• Designed the study on roles of hyaluronic acid on NK cell-based immunotherapy and checkpoint inhibitors with microfluidics • Studied.

Master Of Science - Ms, Biological Engineering

- Leave of absence: Jan 2020 - August 2021

Master Of Research (Mres), Bioengineering, Distinction

Thesis Title: The Role of G Protein-coupled Estrogen Receptor and Pancreatic Cancer Cell-derived Exosomes in the Formation.

Bachelor Of Engineering (Beng), Biomedical Engineering, First-Class Honours

Senior Thesis: Intermittent-Vibration Effect on Pressure Ulcers Formation Under Prolonged Compression: A Senescence-Accelerated Mouse.

Education record

International Student Exchange Program

Education record

Summer School