Brian Danysh Email & Phone Number

Cambridge, Massachusetts, United States

Cambridge, Massachusetts, United States

Cambridge, Massachusetts, United States

Houston, Texas Area

• Performed and supervised laboratory inspections, and inspected, cleaned, maintained equipment and managed laboratory moves and build outs.• Research Team Leader fostered a team environment, educated and trained personnel on good laboratory practices and molecular biology protocols.• Maintained laboratory manuals and standard operating procedures to ensure the integrity, reliability, and reproducibility of results.• Developed collaborative research focusing on research relevant to patient needs by uncovering novel genetic and epigenetic mechanisms of acquired inhibitor resistance in papillary thyroid cancer and how these modifications promote a more aggressive phenotype.• Generating innovative solutions to solve scientific protocol problems and drive their resolution.• Developed upstream processes (i.e stable mammalian gene expression via recombinant viral vectors) to facilitate reliable and replicable experiments.

Houston, Texas

• Collaborated with clinicians, cell and molecular biologists, and physicists to design and evaluate strategies targeting cancers that are resistant to standard treatment options. • Mentored research included:> Investigated the efficacy of Au nanoparticles as targeted ablative agents toward the treatment of endometrial cancer. (Rice University)> Studied acquired molecular adaptions in response to targeted therapies of advanced papillary thyroid cancer. (MDACC)• Acquired expertise in targeted nanoparticles, protein (Western blot) and nucleic acid (real-time PCR) assays.• Trained and educated graduate students on Zeiss confocal microscopes.• Presented scientific data at annual national conferences.• Managed laboratory move.

Houston, Texas

• Designed and evaluated the efficacy of targeting cell-surface glycoproteins in endometrial cancer cells and tissue. • Established a collaborative relationship with a physicist scientist to mechanically destroy cancer cells via transient bubble formed around targeted gold nanoparticles using laser light energy. • My collaborative work led to authorship of two original research manuscripts, one scientific review, and a book chapter.• Developed and wrote two National Institutes of Health (NIH) Postdoctoral fellowship submissions and significantly contributed to the writing of two NIH Research Project Grants (R01).• Presented research findings at a national scientific conference. • Formally presented research progress and grant proposals to department faculty and scientists.• Trained and mentored predoctoral graduate students in molecular biology techniques and experimental design.

Newark, De

• Collaborated with researchers from various scientific fields, including biologists, mechanical engineers, and mathematicians, to develop novel methodologies to measure thicknesses and quantify diffusion rates of molecules within living cellular basement membranes.• Designed and developed transgenic mouse colonies to study ocular lens development.• Developed expertise in confocal microscopy techniques.• Presented scientific data at annual national conferences.

Newark, De

• Highly selective fellowship designed to examined and explored opportunities to improve high school science education.• Spent two full days a week learning teaching strategies from experienced high school teachers in a classroom setting.• Developed and implemented novel strategies to gain student interest while improving test scores.• Designed and oversaw a variety of lab exercises to complement and emphasize lesson plan objectives.

Waltham, Ma

• Developed and tested high availability storage area network (SAN) technology over fibre channel networks for implementation across multiple system platforms at regional data centers.• Developed implementation protocols on new technology and platforms.• Produced technical documentation and lead training seminars to formally train internal engineers and external customers on SAN technology and implementation.

Newark, De

• Designed, implemented, and managed system integration projects, which included system-wide databases, applications, and hardware rollouts for a financial institution with 25,000 employees worldwide.• Served as systems engineer/administrator for several platforms of UNIX OS.• Provided technical support (in-person and over phone) to mainframe and UNIX server users within a financial institution of 25,000 employees worldwide.

Phd, Cell/Cellular And Molecular Biology

Ba, Biological Sciences