Brian Estvander, Ms Email and Phone Number
Proven scientist, researcher, analyst, developer and communicator, drives continuous improvements within processes and projects. Highly dedicated team player with strong history of maintaining high standards in quality control, research, and product development. Adept at building and motivating cross-functional teams to creatively solve problems and enhance productivity while advancing functionality, efficiency, and efficacy. Examples of my achievements include:• Developed novel testing method that quadrupled output, increased accuracy, and reduced waste. • Created award-winning method to show pharmacoequivalence/pharmacodynamics between solubilized/ purified and intact membrane GPCRs. • Introduced now standard in vitro predictive model 3D immunocytochemistry quantitative assay. • Mitigated risk by authoring site-specific cleaning validation master plan (CVMP), averting possible FDA audit failure and penalties. • Spearheaded implementation of protocols and database structure improving data information security measures.Specialties:Product Development, Design & Systems Thinking, Quality Control, Prompt Engineering, Coding, SOPs, Scientific Writing, Research, Cross-Functional Team Building, Project Management , Regulatory Compliance, Life Sciences Research & Development, Digital Ethnography, AI, LLM, GLP, Business Analytics, Quality Management, Process Improvement, Problem Resolution, SME, GMP
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Night CustodianPrairie Hill Ccsd 133 School DistrictIllinois, United States
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Freelance Ai Prompt EngineerOutlier Mar 2024 - PresentRockford, Illinois, United StatesDevelop and review AI model prompting and response for peer-reviewed biology literature for method and results annotations. Bridge gap between worlds of biology, chemistry, pharmacology, mathematical analysis and AI using NLP, SFT, RLHF, Python, PyTorch, R, TensorFlow, LaTex code. AI law and ethics to mitigate risks such as bias, misinformation, and privacy concerns in collaboration with prompt engineers, cyber security engineers, and NLP engineers promoting regulations and ethical standards. - Review and improve AI response for mathematical prompts to eliminate bias, hallucinations, verbosity, and fluff and instill conciseness, clarity and accuracy.- Provide open source contributions to GitHub and Kaggle using coding languages and data base structure design software, including GEO-spatial mapping and small molecule and protein-protein interactions for high affinity drug design like AlphaProteo. -
Quality Control Chemist IiThermo Fisher Scientific 2019 - 2023Rockford, Illinois, United StatesEnsured product quality through rigorous analytical testing on raw materials, intermediates, and finished products to ensure compliance with established specifications and regulatory requirements. Collaborated with cross-functional teams across manufacturing, R&D, and QA to support continuous improvement initiatives.• Authored certificate of analysis for product release.• Forecasted time and resources costs for testing method using data analytic software R and process mapping using Alteryx.• Reduced testing time and cost from two days to four hours with existing resources by developing and validating small molecule/protein conjugation method.• Developed and validated novel well plate binding method; reduced testing time from four hours to one hour and reduced user learning curve, improving intermediate test precision. • Improved consumables purchase and storage Kanban by creating true database using SQLite instead of Excel filing system for material and reagent tracking. • Partnered to establish GHS labeling standard of reagents for all Rockford TFS site. -
R&D Protein Scientist IiThermo Fisher Scientific 2019 - 2022Rockford, Illinois, United StatesSME for two membrane protein research projects. Tracked and allocated consumables, reagents, and capital equipment budget. • Point person for Styrene Maleic Acid Lipid Particles (SMALP) research project plans and established working NDA with university to leverage technology. Identified SMALP variants for solubilization and purification of several membrane protein receptors classes.• Led development and rollout of method validation and specifications for executing in-depth study of gold standard membrane protein and reagent kit for customer use in cryo-EM and nMS.• Established and validated more efficient immunoprecipitation method for the human 80S ribosome for cryo-EM application in conjunction with MCR grant research.
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Quality Control Chemist IThermo Fisher Scientific 2019 - 2020Authored laboratory procedures, supported manufacture and release of pharmaceutical raw materials, intermediates and products, ordered and managed lab stock room and software database for consumables, reagents, and retains.• Achieved 99% first-time pass efficiency rating for all product QC release testing procedures.
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Vice President Operations, InspectorBng-Enterprises Inc 2016 - 2019Rockford, Illinois AreaManaged all aspects of branding and marketing, operations, and quality assurance and control. Specialized in providing structural and component inspection services for residential and light commercial properties including interior and exterior structure, HVAC, insulation, plumbing, electrical, roofing, chimney, and decking.• Achieved 100% customer satisfaction with detailed visual and written documentation and final in-person walk-through.• Earned industry association designations including ICA and InterNACHI, NRSB radon testing, and IAC2 mold testing and remediation certifications.
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Site Quality Control SpecialistMylan 2015 - 2016Rockford, IlEnsured optimum pharmaceutical efficacy through rigorous quality testing systems oversight for stability and dissolution statistical analysis and data trending, noting OOS/OOT anomalies. Developed and implemented QA protocols, risk management processes, and SOPs for internal and external oversight operations and audits. • Authored and implemented Cleaning Validation Master Plan for removable packaging parts.• Managed and executed all environmental QC site procedures including facility temperature, humidity, microbial surface and air testing, cleaning validations, water testing, and pest control. • Commended for excellent work in upholding consistent compliance with ICH guidelines. -
Project Manager Ii, Surgical, Anesthesia And Critical CareBaxter Healthcare 2014 - 2015Round Lake, IlContracted to assume role during employee leave of absence. Led PLC meetings with cross-functional teams across Latin America, Middle East, and Asian Pacific regions. • Streamlined product life cycle for transition of anesthetic glass to aluminum container and governed successful global transition across LATAM, Asia, and New Zealand. -
Product Development Project ManagerFresenius Kabi 2013 - 2014Skokie, IllinoisHired, trained and led five team members and managed GMP analytical and biochemistry cell culture labs in support of peptide injectables. Co-authored method development and validation/transfer protocols. Collaborated with CRO for IQ/PQ/OQ of internal methods/equipment validation. Pharmacological, cell biology, and analytical chemistry SME for company acquisition and CRO opportunities. -
Manager Of Tissue Regeneration, Biological StudiesNanotope, Inc. 2008 - 2012Skokie, IlBuilt biology and chemistry lab from scratch, designing lab, plumbing, electrical, HVAC, and procurement of capital equipment and consumables for in vitro designed assays for regenerative tissue engineering.• Developed quantifiable and reproducible novel 3D immunocytochemistry assay to predict efficacy of peptide amphiphile for studies in animal models in Spinal Cord Injury. • Designed quantifiable and reproducible 3D in vitro scratch assay to predict efficacy of peptide amphiphile in wound healing and cartilage regeneration and piloted in vivo studies with collaborative companies.• Appointed Visiting Scholar at Northwestern University and obtained certification for spinal cord surgery in rodent models at Rutgers University Spinal Cord Regenerative Institute. -
Associate PharmacologistAbbvie 2002 - 2007Abbott Park, Il• Supported HTS efforts for all in vitro radioligand functional, saturation, and competition binding assays utilizing I-125, 3H, and 35S and the Calcium-Influx FLIPR assay in Pain Therapeutics/Cognitive Disorders/Obesity. • Developed novel radioligand binding assay unveiling drug potency equivalence for solubilized and intact membrane receptor and awarded Global Pharmaceutical Research & Development Innovation and Teamwork awards.• Advanced Radiation Safety certified. Controlled Drug Agent sponsored by DEA. • Awarded the first Academic-Abott Labs Scholarship at Rosalind Franklin University of Medicine and Science in the Department of Pharmacology. Partially completed Ph.D. coursework and lab rotations.
Brian Estvander, Ms Education Details
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Cellular Physiology -
Biology, Chemistry
Frequently Asked Questions about Brian Estvander, Ms
What company does Brian Estvander, Ms work for?
Brian Estvander, Ms works for Prairie Hill Ccsd 133 School District
What is Brian Estvander, Ms's role at the current company?
Brian Estvander, Ms's current role is Night Custodian.
What schools did Brian Estvander, Ms attend?
Brian Estvander, Ms attended Northern Illinois University, Northern Illinois University.
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