Brian Vincent Email and Phone Number
Experienced biotech professional who thrives in cGMP regulated environments in order to provide curative and therapeutic treatments to patients who require medicinal remedies in order to live an improved quality of life. My biotech journey afforded me opportunities to acquire skill sets in Manufacturing (Upstream, Downstream, Formulation), Automation, Project Management, Commissioning, Qualification, Validation, and Learning and Development. The past nine (9) years of my career have been dedicated to leadership roles within cGMP MFG teams to deliver production targets of Safety, Quality, Delivery, Inventory, and Production to serve patient needs. Those patients’ medical needs ranged from Enzyme Replacement (Genzyme), Fusion proteins (BMS), Antibody (IDEC, Genentech), Viral Vector Gene Therapy (Thermo Fisher Scientific), or emerging class of programmable RNA therapies (Laronde). I have strong Influencer (I) with shading toward Dominant (D) traits on the DiSC profile. My behavioral traits lend themselves toward high energy, passion, and enthusiasm in order to work together with cross functional teams and team members to drive successful organizational production objectives.I enjoy sharing organizational successes and challenges to enable me to become a better individual, colleague, partner, and friend. I have been afforded opportunities to help grow and develop others around me. I love sharing my industry experiences. I have a strong desire to learn from individuals around me to understand their perspectives on tasks at hand. These shared experiences allow me to build trust and earn respect from others. These interactions allow for a well-rounded version of myself, especially in areas of new opportunities and challenges. The theme a “a team is only strong as the sum of its parts” resonates with me.
Hillevax
View- Website:
- hillevax.com
- Employees:
- 32
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Associate Director Of Manufacturing Compliance And SystemsHillevaxBoston, Ma, Us -
Associate Director Of Manufacturing Compliance & SystemsHillevax Jun 2023 - PresentBoston, Massachusetts, United StatesManaging external manufacturing investigationsManaging GMP Shipments for HIL-214 Norovirus Drug Substance and Drug ProductClosed internal investigationsSupporting client / supplier product disposition activities (i.e., Annex 8, Sample Memo, Certification of Conformance, Supplier Material Specification, etc.)Identified inventory management system optionalityProviding Tech Ops support for Veeva Deviation, CAPA, and Change Control module implementation Authoring and reviewing HILLEVAX SOPs for the Technical Operations team -
Associate Director ManufacturingLaronde Mar 2022 - Apr 2023United StatesAssociate Director of Preclinical & Clinical MFG• Managed Preclinical Manufacturing shifts to produce 150+ eRNA constructs a month• Responsible for Commissioning Qualification Validation (CQV) activities for the site• Responsible for Clinical MFG GMP Readiness for the site• Led GMP documentation / SOP efforts for the site approximately 175 SOP’s for GMP Production• Generated Dolomite LNP SOP for Preclinical MFG• Revised and generated Preclinical MFG protocols / SOPs to enable standard training for associates• Implemented Qualer an Assessment Management System (AMS)• Generated Preclinical MFG production Visio process flow diagrams / roadmaps • Generated MFG department metrics -
Manager Learning & DevelopmentThermo Fisher Scientific Jul 2021 - Mar 2022Lexington, Massachusetts, United StatesBuilding the Learning & Development department and capabilities for the site• Implemented the VVS LEX site training team• Led Success Factors Learning Management System (SFLMS) migration at the VVS LEX site• VVS LEX site SFLMS Admin (i.e., managed employee learning / report running)• Created and revised SFLMS Curricula and Assignment Profiles• Led digital strategy AR/VR/MR Training efforts for VVS LEX incorporating MS Dynamics Guides 365 and Microsoft HoloLens• Implemented Remote Assistance capabilities for the site• Implemented iCellis Digital Twin for VVS LEX MFG Training• Produced cross functional training curriculum maps for all VVS LEX site departments -
Viral Vector Service Upstream SupervisorThermo Fisher Scientific Feb 2019 - Jul 2021Lexington, Massachusetts, United StatesManaged an Upstream Team of 10x direct reports through Facility CQV -->GMP Readiness -->Initial Phase 3 commercial client batches• Led a team of five executing 45x aseptic host cell operations a month• Managed a team of five responsible for executing 6x iCELLis bioreactors / Single Use Mixing systems in 25000 sq ft of qualified production space with a 4-day batch cadence• Directed a team of document writers for client batch document change requests (SOP, PBR, WI) • Trackwise change control associated with Pall vendor data changes for next generation iCELLis bioreactor within batch production documentation• Pall iCELLis 500+ Subject Matter Expert (SME) for iCELLis setup, inoculation, transfection, and harvest• Developed global Pall iCELLis On the Job Training (OJT) aide• Developed client specific process flow diagrams and Bill of Material creation• Cross functional site visits to train and run client viral gene therapy campaigns in Cambridge and Alachua for iCELLis best practices• Lexington facility start up -
Quality Assurance SupervisorBristol Myers Squibb Feb 2018 - Feb 2019Devens MassachusettsLSCC Field Quality Assurance Supervisor• Managed a team of four (4) field quality assurance leads to support 24 / 7 coverage for LSCC commercial production -
Project Management Team LeadBristol Myers Squibb Aug 2017 - Feb 2018Devens MassachusettsPMO Lead (rotational assignment)• Managed eight (8) cross functional manufacturing, warehousing, and quality control projects. -
Large Scale Cell Culture Supervisor - Downstream OperationsBristol Myers Squibb Jul 2015 - Aug 2017Devens MassachusettsLSCC Downstream Purification SupervisorManaged a team of 14 direct reports in fully automated DeltaV / Syncade 120k liter facility with a team that consistently met or exceeded expectations for safety, quality, production targets (kg/per batch, batch through put), cadence, and right first time -
Lscc Downstream Technical LeadBristol Myers Squibb Jan 2013 - Jul 2015Devens MassachusettsLSCC Downstream Purification Technical Leader• Led a Downstream Purification shift of 14-night shift direct reports to produce 150 batches of Orencia at the fully automated 120,000L Large Scale Cell Culture facility
Brian Vincent Education Details
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Biochemistry
Frequently Asked Questions about Brian Vincent
What company does Brian Vincent work for?
Brian Vincent works for Hillevax
What is Brian Vincent's role at the current company?
Brian Vincent's current role is Associate Director of Manufacturing Compliance and Systems.
What schools did Brian Vincent attend?
Brian Vincent attended University Of New Hampshire.
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