Brian M. Davis, Ph.D. Email & Phone Number

Albany, Ny, Us

Albany, New York Area

- Led 12 projects at GE Research, including management and coordination of junior staff and technical team.- Role required active communication to maintain relationships with stakeholders at GE Research, GE Healthcare, government program managers, and external customers.- Initiated programs and secured research funding from GE and from government agencies including FDA, NIH, FNIH, DARPA, NIJ and IARPA, exceeding $14 million in total funding.- Built and maintained external partnerships and collaborations with academia, government, small businesses and large businesses.- Coordinated multidisciplinary teams to meet program deliverables.- Managed, coordinated, trained and mentored more than 10 junior staff scientists and interns. - Assisted GE Healthcare in acquisition target evaluations, due diligence and strategy.- Provided technical guidance and expertise to dozens of projects at GE Research and GE Healthcare; program topics include AAV manufacturing, CAR-T cell therapy, lentiviral gene therapy, viral vector production, DNA delivery, pluripotent stem cells, bioreactor cell culture, bioprocessing, cell harvesting, virus clearance, microRNA reporters, microfluidics, biomarker characterization, biodefense and forensics.- Principal investigator on three IRB approved protocols.- Established lab-wide safe work practices and standard operating procedures for handling biologic materials.- Authored 30+ internal reports, 40+ reports to government, and submitted 30+ IP disclosures.

Albany, New York Area

- Secured CDMRP funding to perform high throughput screening using lentiviral vector based shRNA libraries to identify genes that control chronic myelogenous leukemia cell replication and apoptosis.- Developed tightly regulated inducible lentiviral vectors for cDNA and shRNA expression, compatible with normalized full length cDNA libraries.- Supervision of 3 laboratory technicians and mentor to junior associates.- Co-authored 4 peer reviewed publications.- Member of American Association for Cancer Research

Gaithersburg, Md

- Contributed to IND application for first clinical application of a lentiviral vector that subsequently entered Phase 1 and 2 clinical trials.- Creation and analysis of lentiviral vectors for hematopoietic stem cell gene therapy to treat HIV and for in vivo selection.- Characterized human hematopoietic stem cell transduction in immunodeficient NOD-SCID and SCID-hu mice.- Invented an improved protocol for human hematopoietic stem cell transduction using ABC transporter substrates and inhibitors.- Supervision of 2 laboratory technicians.- Authored 2 first author peer reviewed publications and contributed to 3 additional peer reviewed publications.- Member of American Society of Gene Therapy

Doctor Of Philosophy - Phd, Molecular Virology/ Gene Therapy

Activities and Societies: American Association for Cancer Research * American Association for the Advancement of Science * American.

Bachelor Of Science - Bs, Cell/Cellular And Molecular Biology, Magna Cum Laude

Activities and Societies: Teaching Assistant for Cell and Molecular Biology, Cell and Molecular Biology lab and Genetics * Musician.