Brian Rabkin Email and Phone Number
California, United States
Brian Rabkin's Location
San Francisco Bay Area, United States, United States
Brian Rabkin's Contact Details
Brian Rabkin work email
- Valid
Brian Rabkin personal email
n/a
About Brian Rabkin
Life Sciences leadership professional with over 16 years of industry experience developing next-generation sequencing (NGS) systems, assays and applications. Combined expertise in molecular biology, engineering, microfluidics, and software programming for development of integrated systems to perform automated molecular assays and sequencing.- Led the Roche end-to-end sample to answer development activities that integrated sample automation, sequencing and informatics. - Led the Roche nanopore sequencer’s research and development activities to achieve feasibility and meet product specifications.- Led and participated in core teams to advance product development lifecycle from concept to launch for GAIIx, HiSeq, MiSeq, MiSeqDx, TruSeq Custom Amplicon Assay, Nextera Assay, and iSeq Sequencer. Core Competencies: Cross-functional Team Leadership • Next Generations Sequencing (NGS) • Molecular Assay Development on Microfluidic Systems • Design Control for FDA clearance (510(k), IND, IDE) of Products • Instrument & Method Development • Product Development Lifecycle • Software Development & Data Acquisition • Analytical/Molecular Laboratory Techniques • Bioinformatics • Molecular Biology • R&D • Project Management • Workflow Automation
Brian Rabkin's Current Company Details
Brian Rabkin Work Experience Details
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Lead Biotechnology ConsultantBrian Rabkin ConsultingCalifornia, United States
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Director Of Engineering – Life SciencesEnterprise Peak Mar 2023 - PresentChicago, Il, UsPart of the Enterprise Peak engineering advisory practice focused on running R&D engagements in the Medical Device and Life Sciences sectors. Programs include combination of software, hardware, clinical assays as well as the overall architecture of complex systems.
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Freelance Leader Biotechnology Consultant.Freelance Dec 2022 - Present• Provided technical expertise in molecular biology assay development, NGS, instrumentation, and bioinformatics to consulting organization and clients.• Developed assays, algorithms, machine learning models, instrumentation, cloud pipelines, and data visualization in life sciences.• Collaborated with cross-functional teams to drive innovation and deliver high-quality solutions in biotechnology consulting.
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Director Of Engineering And Life SciencesBeckman Coulter Life Sciences Mar 2023 - Oct 2024Indianapolis, Indiana, UsDirected cross-functional algorithm and data science teams to develop AI/ML models predicting diagnostic assay outcomes during new product development, enhancing accuracy and decision-making.* Spearheaded a cloud-based pipeline for data engineering, inference, analysis, and visualization, reducing manual workflows and improving data accessibility.* Served as project core team representative, aligning algorithm development with cross-team product goals and timelines. -
Director In R&D Life SciencesNautilus Biotechnology Jul 2021 - Aug 2022San Carlos, California, Us -
Director System Development Lead, SequencingRoche Sequencing Usa Feb 2019 - Jun 2021Indianapolis, Indiana, Us -
Director Technology Development Lead, SequencingRoche Sequencing Usa Jun 2017 - Jun 2021Indianapolis, Indiana, Us• Direct research and development planning, characterization and integration efforts for developing a novel IVD Nanopore DNA Sequencer. • Coordinate a cross-disciplinary team and balance the efforts of Research and Development to deliver a sequencing platform that meets the performance and quality targets defined for the IVD product.• Lead the planning, evaluation and characterization of the chemistry, nanopores, hardware, software, bioinformatics, fluidics, and other aspects of the prototype platform.• Oversee internal and consultant experts in biology, chemistry, hardware, software, bioinformatics, fluidics, and mechanical engineering to specify and produce a prototype platform.
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Director Of Research And DevelopmentBerkeley Lights, Inc. Jan 2017 - May 2017Emeryville, Ca, Us• Led a diverse team of experts towards a commercially viable Searchlight Cellular Therapy Manufacturing Platform that can be deployed at point of care or at a centralized facility.• Worked directly with external collaborators to translate and optimized ETC, TIL and CAR-T/TCR immunotherapy workflows into commercially viable products.• Led a team developing integrated fully disposable micro- and macro-fluidic consumables for performing end-to-end immunotherapy workflows that are GMP compliant without the need for a GMP facility.• Developed single cell genomics applications implementing aqueous-in-oil sample preparation methodologies.• Originated the concepts and proved feasibility of two novel FACS devices, and filed for multiple patents.• Implemented electronic laboratory notebook system using Confluence and AGILE SCRUM methodologies to improve the integration of the engineering and biology teams to accelerating the rate of development. -
Principal Scientist - Research And DevelopmentBerkeley Lights, Inc. Jun 2016 - May 2017Emeryville, Ca, Us• Led a diverse team of experts towards a commercially viable Searchlight Cellular Therapy Manufacturing Platform that can be deployed at point of care or at a centralized facility.• Worked directly with external collaborators to translate and optimized ETC, TIL and CAR-T/TCR immunotherapy workflows into commercially viable products.• Led a team developing integrated fully disposable micro- and macro-fluidic consumables for performing end-to-end immunotherapy workflows that are GMP compliant without the need for a GMP facility.• Developed single cell genomics applications implementing aqueous-in-oil sample preparation methodologies.• Originated the concepts and proved feasibility of two novel FACS devices, and filed for multiple patents.• Implemented electronic laboratory notebook system using Confluence and AGILE SCRUM methodologies to improve the integration of the engineering and biology teams to accelerating the rate of development.
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Staff Genomics Scientist / BioengineerVerily Life Sciences Jun 2015 - Mar 2016Dallas, Texas, Us• Led an effort to develop the high-throughput single-cell analysis program at Verily to elucidate the cellular heterogeneity in human health for therapeutic discovery and monitoring of disease.• Evaluated and developed methods and platforms for the enrichment, isolation, genomic and transcriptional analysis of immune and cancer cells from liquid or solid biopsies, including circulating tumor cells (CTCs).• Studied the ability of single-cell analysis techniques to differentiate between closely related T cell subtypes at the phenotypic, functional and receptor specificity level.• Contributed to the early phase development of microfluidics systems for cell isolation and reverse transcription (RNAseq) through sequencing library preparation, including droplet-based systems.• Co-invented and filed for three patents on micro-FACS and light sheet imaging cytometry. -
Sr Scientist Technology DevelopmentIllumina Jan 2012 - Apr 2015San Diego, Ca, Us• Contributed to the early phase development of multiple sequencing platforms, including the development and implementation of hardware, chemistry and software for single molecule sequencing and fully integrated sample-to-answer sequencing (Firefly). • Served as Project Core Team integration lead for the Illumina MiSeqDx Cystic Fibrosis program. • Developed custom prototype instruments for sequencing and sample preparation. Including optics, mechanics, sensors, digital and micro-fluidics, control and analysis software, and on instrument chemistry.• Developed computational methods for signal processing from custom CMOS imagers and single-cell sorters.• Developed bioinformatics programs for data aggregation and visualization to determine the underlying causes (hardware, software and chemistry) of errors in sequencing data. -
Sr Scientist Technology DevelopmentIllumina Jan 2012 - Apr 2015San Diego, Ca, Us• Contributed to the development of multiple Illumina sequencing platforms (GA, GAII, GAIIX, HiSeq, MiSeq), including the design, implementation and evaluation of hardware, chemistry and software. • Served as Project Core Team integration lead for TruSeq Amplicon targeted sequencing sample preparation kit, a sequencing platform and a diagnostic product.• Part of the select Peer Technical Review team to aid senior management in assessing major development projects.• Managed and directed members of the systems integration team and development project sub-teams during the development phases (concept – breadboard – production).
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Sr. Systems Integration ScientistIllumina 2008 - Nov 2012San Diego, Ca, Us• Contributed to the development of multiple Illumina sequencing platforms (GA, GAII, GAIIX, HiSeq, MiSeq), including the design, implementation and evaluation of hardware, chemistry and software. • Served as Project Core Team integration lead for TruSeq Amplicon targeted sequencing sample preparation kit, a sequencing platform and a diagnostic product.• Served on Peer Technical Review panels for many major development projects.• Managed and directed members of the systems integration team and project sub-teams during the development phases (concept – breadboard – production).
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Postdoctoral FellowJoint Genome Institute Jul 2005 - Jan 2008Berkeley, California, UsGenomic Technologies Program * Led the development of methods that combine fluorescence activated cell sorting (FACS) and DNA sequencing for the metagenomic analysis of naturally occurring and engineered microbial communities with the aim of improving biofuel production and pollution control through bioremediation. * Developed high-throughput multiplexed methods of DNA sample preparation and sequencing. * Devised methods for the amplification and sequencing of the genomes of individual cells of unculturable microorganisms. -
Graduate Research Assistant (Ph.D.), Dept. Of BioengineeringUniversity Of Washington 2002 - 2005Seattle, Wa, Us* Engineered and evaluated non- and minimally-invasive ultrasound surgical and imaging devices for the treatment of ovarian cancer and cessation of bleeding.* Developed a Color-Doppler ultrasound imaging method for the real-time guidance and monitoring of high intensity focused ultrasound (HIFU) surgery.* Researched the physiological and morphological affects of ultrasound ablation of blood vessels and tumors.* Developed an immunocompetent orthotropic isograft mouse model of ovarian cancer. -
Graduate Research Assistant (M.S.), Dept. Of Bioengineering And Electrical EngineeringUniversity Of Washington 1999 - 2002Seattle, Wa, Us* Developed a novel protein separation and analysis instrument for the isoelectric fractionation (IEF) of proteins in free solution for proteomic applications.* Built a custom capillary isoelectric focusing (CIEF) instrument for protein separation and quantification.
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Life Science Research AssociateStanford Human Genome Center 1998 - 2000* Sequenced the first draft of the human genome.* Mapped and sequenced a portion of the Human Chromosome 4.* Developed bioinformatics software for tracking experiments and samples and for the analysis of data using Perl CGI scripts implemented through dynamic web pages and UNIX.* Developed a cultured bacteria library for tracking human artificial clones used in the sequencing pipeline.
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Research AssistantNasa-Ames Research Center And Dept. Of Medicine, University Of California, San Francisco 1997 - 2000Washington, Dc, Us* Researched the effects of loading, hyper-loading and unloading on bone mineralization in-vivo in rats.* Designed an in-vivo strain gauge telemetry system for studying the affects of age on bone remodeling in rats.* Studied the in-vitro remodeling of bone specimens by cultured osteoblasts and osteoclasts.
Brian Rabkin Skills
Life Sciences
Bioinformatics
Dna
Dna Sequencing
Biotechnology
Sequencing
Biochemistry
Cell Culture
Cell
Assay Development
Molecular Biology
Genomics
Pcr
Genetics
R&d
Fluorescence
Research And Development
Brian Rabkin Education Details
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University Of WashingtonBioengineering -
University Of WashingtonBioengineering
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Uc Santa BarbaraMarine/Aquatic Biology
Frequently Asked Questions about Brian Rabkin
What company does Brian Rabkin work for?
Brian Rabkin works for Brian Rabkin Consulting
What is Brian Rabkin's role at the current company?
Brian Rabkin's current role is Lead Biotechnology Consultant.
What is Brian Rabkin's email address?
Brian Rabkin's email address is br****@****lus.bio
What schools did Brian Rabkin attend?
Brian Rabkin attended University Of Washington, University Of Washington, Uc Santa Barbara.
What skills is Brian Rabkin known for?
Brian Rabkin has skills like Life Sciences, Bioinformatics, Dna, Dna Sequencing, Biotechnology, Sequencing, Biochemistry, Cell Culture, Cell, Assay Development, Molecular Biology, Genomics.
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