The Adkins Academy, Inc prepares individuals to recognize how to solve complex problems and perform well on standardized exams as they aspire to matriculate into college, professional school or graduate school. We provide insightful technical guidance and professional development training to aid in the application process. Our team of professional subject experts are committed to empowering futures for all students regardless of location, aspiration, or ones initial level of competency. •Developed: business strategy, academic content, electronic communications, SOPs, virtual education atmosphere •Oversaw: financial, marketing, promotional & client acquisition duties nationally, along with content development, community outreach initiatives, talent acquisition and retention, 9 professional consultants and 2 administrators, scheduling and payroll, group academic instruction, >250 youth & adults impacted since opening; 400% growth YTD AdkinsAcademy.com

Biological Sciences InstructorDepartment of Natural Sciences

•Community Based Programs: Lead the research, development, coordination, negotiations, and implementation of a program that provides members with community resources that support and educate members regarding various disease states.•Obstructive Sleep Apnea Diagnosis & Management Program: Lead the development & implementation of an OSA Community Based Program to cost-effectively diagnose and manage members with OSA, researched ROI, negotiated directly with vendor, created the incentive structure and SLA•Specialty Pharmacy Programs: Analyzed and negotiated proposals from multiple Pharmacy Benefit Managers (PBMs) considering aspects of Prior Authorization & Rebate structuring, Formulary & Utilization Management, Member Coordination & Education Programs, Medication Adherence Programs, & Medication Supply Chain Management; worked with multi-disciplinary teams to provide clinical and business insight on $50-$100M projects; over 3.1M lives affected, greater care coordination and provider access for members•Hospice & Palliative Care Pilot: Researched utilization and quality metrics, discussed potential partnerships with executive teams, researched and presented emerging industry innovations; Results: Development of Palliative & Hospice Care Initiatives supporting over 20,000 – 30,000 lives annually; increasing member autonomy in End-of-Life Care decisions and availability of hospice and palliative care options.•Medication Therapy Management Pilot: Lead ROI research initiatives evaluating member impact, developed MTM program components and contract, lead Federal Employee Program-CareFirst-vendor meetings; Results: $125,000 budget, >150 lives•Enhanced Monitoring & Medication Adherence Programs: Provided clinical insight and comparative analysis, aided in Cost Avoidance ROI modeling, participated in operational discussions with executive team and vendors. Results: $500M in potential cost avoidance, reduced hospital readmissions, improved care coordination, 300K lives

•Research: Developing a better understanding of endothelial wall dysfunction and the inflammatory reaction resulting from exposed to cell free hemoglobin combined with bacterial antigens as seen in sickle cell patients with sepsis/bacteremia or hemolytic uremic syndrome complicated by bacteremia •Techniques: Conducted animal exchange transfusion experiments, comparative gross and histologic assessments of control vs. pathologic tissue, utilized immunohistochemistry staining with highly selective antibody markers, western blot and functional / enzymatic analysis using homogenized tissue lysate, chemiluminescence immunoassays•Results: Significantly higher levels of inflammatory and oxidative stress markers seen in multiple organs including the lungs, kidneys, brain, heart, and spleen.•Presented research finding before senior managers, expert scholars, and regulators of FDA’s CBER & CDER Divisions.•Worked on New Drug Application proceedings for blood substitute and hereditary angioedema products for market.

•Supervised 10 medical student counselors and over 200 high school students from around the country and the US Virgin Islands during 2 summer programs, all students received personalized mentoring and constructive performance feedback •Oversaw Operations for 2010 summer program: o Secured travel and housing accommodations for all participants o Edited and Developed official program booklet content for participants and the granting agency o Delivered lectures on college matriculation and scholarship/financial-aid acquisition o Developed Team Workshops: Persuasive Essay Writing, SAT/ACT Testing, College Survival Skills •Oversaw NAAYI Program Logistics including interactive visits to the National Institutes of Health, U.S. Capitol, National Library of Congress, Howard University College of Medicine / Dentistry, Washington and Baltimore historical sites, Health And Human Services Administration Building, as well as the Food And Drug Administration •Developed and reported on post-program evaluations per specific requirements of the granting agency•Represented the NAAYI Program on an NMA Outreach Initiative Panel at the 2010 NMA Annual Conference•Over 90% of NAAYI Summer students matriculated into college; a majority of whom have chosen a STEM major

• Research: Investigated Human Papilloma Virus Virus-Like Particle neutralization using the JT Schiller protocol o Results: Established a standard protocol for assessing potential monoclonal antibodies for their vaccine potential o Techniques: Cell Culture, VLP Transfections, Chemiluminescence immunoassays, Antibody neutralization analysis, western blot analysis, and qualitative and quantitative statistics. • Presented research finding before staff and senior level scientists at ASU Biodesign Institute and HUCM

• Investigated the role of Scaffold Attachment Factor B1 (SAFB1), a proposed estrogen receptor co-repressor, using SAFB1 knock-out mice and breast cancer cell lines induced with different estrogen derivatives. When the SAFB1 gene was restored via transfection, ER co-repression was shown to be significantly greater compared to SAFB1 KO. • Techniques: Cell culture, plasmid preparation, proliferation, and extraction, animal KO modeling, western blot Publication: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069606/Margarita Ivanova, Klaudia M Dobrzycka, Shiming Jiang, Kai Michaelis, Rene Meyer, Kaiyan Kang, Brian Adkins, Oleg A. Barski, Jana Divisova, Adrian V Lee, Steffi Oesterreich. The Scaffold Attachment Factor B1 Functions in Development, Growth, and Reproduction. Mol Cell Biol. 2005 Apr;25(8):2995-3006.

• Investigated the role of Scaffold Attachment Factor B1 (SAFB1), a proposed estrogen receptor co-repressor, using SAFB1 knock-out mice and breast cancer cell lines induced with different estrogen derivatives. When the SAFB1 gene was restored via transfection, ER co-repression was shown to be significantly greater compared to SAFB1 KO. • Techniques: Cell culture, plasmid preparation, proliferation, and extraction, animal KO modeling, western blot