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Results-oriented Senior Engineer/Senior Scientist with more than 10 years of hands on experience in engineering, biomedical and optical technologies in academia, clinical trials, and medical device industry. Self-motivated with ability to handle several projects while managing others in an R&D setting. Proven track record of meeting deadlines and budget. Well developed communication skills. Principal author in 8 peer reviewed manuscripts, with16 total.Specialties: • Development of FDA approved Class II device• Manufacturing Process Development• Root Cause Analysis, CAPA, FMEA• Verification and Validation • Analytical and numerical modeling• Fluorescence & Reflectance Spectroscopy • Managing technical teams• Clinical data acquisition & statistical analysis• Liaison between engineers and physicians• ISO 13485 and cGMP regulations• Laser-Tissue Interactions, Biomedical Optics• Study Design, DOE• FDA submissions, IDE & 510(k)
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Chief Scientific OfficerForward Science Jan 2012 - PresentHouston, Texas, UsForward Science Technologies LLC is a privately held medical device company based in Houston, Texas. With the goal to move science forward, Forward Science has a robust product pipeline to fill the needs of the medical industry. -
Manager Of Technical ServicesMedical Metrics, Inc. Jun 2010 - May 2013Houston, Texas, Us• Provides imaging and clinical trial consulting services for client companies• Develops technical proposals and secures consulting contracts (≤ $750k)• Manages team of scientists, radiologists, and analysts to complete projects on time and budget • Creates Imaging Charters (Radiographic Evaluation Protocols) to garner FDA approval for IDE and Post-Market spine and orthopedic clinical trials • Address responses to FDA Deficiency Letters for client companies• Increases company revenue by encouraging consulting services• Lead on Quality Initiative; Developing radiographic atlases to improve intra- and inter-observer reliability -
Sr. Development ScientistRemicalm Llc Oct 2007 - Jun 2010• Scientific Lead on project redesigning portable cancer screening device that reduced failure rate by more than an order of magnitude. Developed models to enhance vascular contrast with limited available excitation spectra. • Scientific/Engineering Lead developing an existing prototype spectrometer into a cervical cancer diagnostic device that was prepared for Phase III Clinical Trials. Improved SNR of spectrometer by more than 15x and increased dynamic contrast of imaging spectrometer more than ten-fold. Redesigned hardware to increase reliability. Developed the calibration protocol for final test and traceability purposes.• Directed contract manufacturer in all scientific process control issues related to manufacturing the final product. Optimized design and assembly processes to increase spectral radiant flux by more than 50%.• Assisted Intellectual Property Attorney with prosecution of United States and foreign patents of novel company technology.• Fielded scientific questions from dentists. Principal voice of customer within company.
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Sr. ScientistUt Md Anderson Cancer Center Dec 2003 - Jul 2007• Co-Director, Instrumentation Core of P01 grant (~$15M). Team Manager for Quality and Security of clinically acquired data across North America. Project Manager for embedded real-time Quality Control software of research grade instrumentation for Phase II and III clinical trials. Assisted in clinical trial design and statistical analysis.• Manager of 9 in the Engineering & Data Group (1.6Tb of data). Technical Lead for team of physicians, engineers, and statisticians in analyzing spectroscopic data. Streamlined data transfer between clinical sites and main server. • Integrated statisticians, programmers, data base managers, and engineers into a cross functional team increasing interaction and results. Mentored junior level engineers and graduate students.• Project Lead for redesigning fluorescent spectroscopic fiber optic probe for enhanced light transmission and 800% reduction of probe autofluorescence.
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Graduate Student And Postdoctoral Research AssociateRice University Jan 1998 - Jan 2004Houston, Tx, Us• Designed novel methods to increase epidermal protection in response to laser irradiation.• Scientific Lead collaborating with physicians investigating laser treatment to reverse hearing loss.• Mentored and supervised four undergraduate students conducting spectroscopic (FTIR) and radiometric measurements of chemical that had not been quantified before in liquid phase.• Quantified histological sections for in vivo effects of laser-induced vascular response, determining optimal wavelengths for vascular coagulation.• Increased epidermal protection in response to laser irradiation allowing darker skinned individuals to benefit from cutaneous laser therapy. -
Research AssistantCandela Corporation May 2001 - Aug 2001• Assisted R&D team in pre- and post-production R&D of medical laser systems• Developed LabVIEW virtual instrument to monitor thermocouple and infrared temperature measurements• Prepared written reports and white papers• Researched viability of novel treatment using existing medical laser
Brian Pikkula Skills
Brian Pikkula Education Details
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Rice UniversityBioengineering And Biomedical Engineering -
Rice UniversityBioengineering -
Louisiana Tech UniversityElectrical Engineering Emphasis -
Louisiana Tech UniversityBiomedical/Medical Engineering
Frequently Asked Questions about Brian Pikkula
What company does Brian Pikkula work for?
Brian Pikkula works for Forward Science
What is Brian Pikkula's role at the current company?
Brian Pikkula's current role is Chief Scientific Officer, Forward Science.
What is Brian Pikkula's email address?
Brian Pikkula's email address is bp****@****lid.com
What is Brian Pikkula's direct phone number?
Brian Pikkula's direct phone number is +183252*****
What schools did Brian Pikkula attend?
Brian Pikkula attended Rice University, Rice University, Louisiana Tech University, Louisiana Tech University.
What skills is Brian Pikkula known for?
Brian Pikkula has skills like Medical Devices, Biomedical Engineering, Fda, R&d, Iso 13485, Design Of Experiments, Matlab, Project Management, Manufacturing, Medical Imaging, Optics, Clinical Trials.
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