Brooke Mcknight, Phd Email & Phone Number

Product manager for Invitae RUO oncology (formerly Archer Dx) NGS distributed kit business. Launched and supported seven new solid-tumor next-generation sequencing panels in partnership with global marketing, sales, R&D, software, and field scientist teams. Created business cases for new market opportunities and shared with core leadership team through product definitions, vision documents, market segmentation analysis, and voice of customer feedback. Led a cross-functional team of business development, marketing, manufacturing, and scientist colleagues to rebrand customer-facing protocols, product inserts, consumables, and website content from Archer Dx to Invitae.

Ann Arbor, Michigan

Oncology clinical and technical subject matter expert providing informatics support to cross-functional teams of R&D scientists, business development, and medical affairs for the development of Ion Torrent next-generation sequencing (NGS) assays and sample-to-answer solutions. Curated content sourced from drug labels, clinical guidelines, and global clinical trials for inclusion in genomic analysis software tool Oncomine Reporter. Authored external customer-facing documents describing clinical significance of actionable NGS biomarkers focusing on oncogenesis pathways, gene variant prevalence, and diagnostic, prognostic, and theranostic implications. Developed and prioritized new clinically-relevant oncology content for new product initiatives and inclusion in Oncomine Reporter reports.

Greater Detroit Area

Investigated breast (HER2+ and TNBC) and pancreatic tumor response to treatment (FDA approved small molecule inhibitors and immunotherapy) through development and characterization six Cu-64 and 89-Zr labelled antibody PET probes.Technical Experience: CT/PET machine operation, analysis using PMOD, AsiPRO (IDL), and AMIDE software, cancer cell culture, western blot and treatment studies, radioimmuno assays, radiochemistry, antibody conjugationIn vivo mouse handling experience including: survival surgery, xenograft, oral gavage, tail vain injection, and gross anatomy. Ex vivo experience with cryostat tissue sectioning, immunohistochemistry, and autoradiographyResearch Experience: Oncology, Immunology, Pharmacology, Breast Cancer, Pancreatic CancerMentorship Experience: Laboratory mentor (4 students, Viola Lab), Introduction to Cancer Biology Study Group Faciliatator (Cancer Biology Graduate Program)

Ann Arbor, Mi

Ginsburg LabSequenced the TMPRSS6 coding sequence in a patient with IRIDA and identified 3 possible disease causing SNPs. Assisted in exploring the mechanism in which pancreatic enzymes move through the endoplasmic reticulum.Technical experience: CRISPR-Cas9, co-immunoprecipitations, western blots, genotypingRothberg LabAssisted a clinical lab in the endocrine and diabetes clinic studying obesity and methods for effective weight loss management by observing and collecting patient data during physical stress tests.Technical Experience: Data analysis (Excel), StatisticsHan LabHelped develop an in vivo renal genomic screen in drosophila by conducting genetic crosses and colony maintenance in drosophila melanogaster and preparing samples for transmission electron microscope (TEM)

Ann Arbor, Mi

Developed and implemented weekly 2-hour lesson plan to current biochemistry students within 3 days of attending lecture and created worksheets, games, and quizzes to communicate information effectively for multiple learning styles

Doctor Of Philosophy (Ph.D.), Cancer Biology

Activities and Societies: World Molecular Imaging Society (WMIS), American Association for Cancer Research (AACR), American Association.

Bachelor Of Science (B.S.), Cell/Cellular And Molecular Biology

Activities and Societies: Women in Science and Engineering (WISE) - Summer Camp Leader, Females Excelling More in Math, Engineering.