Matthew Brune Email & Phone Number

Washington, DC, US

San Carlos, California, United States

• Managed clinical trial data collection efforts at biotech startup, ensuring accurate and complete data and compliance with federal regulatory requirements
• Developed strategy to reduce time to lock database from 6 weeks to 1 week, exceeding industry standard and allowing company to report financial results on expedited basis
• Oversaw development and implementation of Python and SAS data quality reports
• Led weekly cross-functional meetings of staff, vendors, auditors, and clinical site operatorsto ensure regulatory compliance and weekly data cleaning targets
• Authored standard operating procedures, work instructions, and audit responses for use bystaff, clinical site operators, and auditors

Rockville, Maryland, United States

• Developed and maintained SAS-based clinical trial databases managed by contractingorganization, including building data entry forms and conducting user acceptability testing
• Analyzed data using Excel and SAS to identify anomalous data and initiate corrective action
• Communicated protocol and data issues to project sponsors and clinical site operators andproposed solutions to address data problems

Greater Philadelphia Area

• Led implementation of medical testing platform, which reduced cost of vitamin D andimmunosuppressant drug testing from $12 to $2 per sample
• Used R and ggplot2 data visualization tools to designed and implement workflow forspecimen receipt, clinical reporting processes, and academic publications
• Led transition of instrument interfaces to Epic electronic medical records system
• Oversaw department’s response to accreditors’ request for inspection
• Identified areas for business growth and presented findings to hospital administrators,including cost analysis for service expansion

Bethlehem, PA

• Led effort to open clinical toxicology laboratory serving pain management providers
• Drafted operating processes and documentation necessary to qualify for licensure
• Authored standard operating procedures, audit reports, testing validation reports
• Established medical testing for billing per ICD-9 and ICD-10

Pittsburgh, PA

• Organized data for a study of auditory brainstem response (ABR) in gene knock out mice to determine pain threshold.
• Treated gene knock out mice ear hair cells with cisplatin to determine ototoxicity levels.
• Performed analysis of CT scans of temporal bones to determine a correlation between pneumatic quality of temporal bone and middle ear disease.
• Presented the data from the ABR study at an undergraduate research poster session.

Philadelphia, PA

• Evaluated candidate genes for atrial septal and ventricular septal defects by PCR and sequencing data analysis to find a genetic cause for those disease.
• Prepared and conducted experiments and analyzed the data.
• Attended lectures relating to genetic disorders, clinical practice, and ethic and practical issues in modern genetics.

Philadelphia, PA

• Evaluated candidate genes for Hypoplastic Left Heart Syndrome defects by PCR and sequencing data analysis to find a genetic cause for those disease.
• Prepared and conducted experiments and analyzed the data.
• Attended lectures relating to genetic disorders, clinical practice, and ethic and practical issues in modern genetics.

Master Of Science - Msc, Molecular Medicine

Bachelor Of Science, Chemistry

High School