Scott Burley Email & Phone Number
@cglifesciences.com
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Who is Scott Burley? Overview
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Scott Burley is listed as Account Manager at Chemglass Life Sciences Covering Southern California, Arizona and Colorado at Chemglass Life Sciences, a with 115 employees, based in San Diego, California, United States. AeroLeads shows a work email signal at cglifesciences.com and a matched LinkedIn profile for Scott Burley.
Scott Burley previously worked as Account Manager at Chemglass Life Sciences and Scientist I at Genomics Institute Of The Novartis Research Foundation. Scott Burley holds Master Of Science (M.S.), Synthetic Organic Chemistry - Natural Products from San Diego State University.
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About Scott Burley
Master's Degree in Synthetic Organic Chemistry with graduate level course work and research experience in Organic synthesis. Research projects consisting of development of a short library-optimized route to the ergoline skeleton. The route was designed and structured to introduce diversity late in the synthetic scheme allow for the ease of the creation of a new synthetic library. A highly functionalized pyridine ring was utilized for the creation of an (indolylmethyl)pyridine structure by a Fischer indole synthesis. Diverse substituents on the phenylhydrazine component thus become incorporated into the indole ring and are carried through the remaining synthetic steps. Immediately following the Fischer reaction, the ergoline skeleton is constructed via a palladium assisted intramolecular cyclization, and in the final steps of the scheme the pyridine ring is modified and reduced. The resulting library of ergolines promises to be an outstanding tool for investigating the pharmacology of neuroreceptors. Burley, S. D.; Lam, V. V.; Lakner, F. J.; Bergdahl, B. M.; Parker, M. A., New Route to the Ergoline Skeleton via Cyclization of 4-Unsubstituted Indoles. Org. Lett. 2013, 15, 2598.Secondly, A library-optimized route to a class of dihydropyranobenzimidazole inhibitors was designed previously. These inhibitors had earlier been shown to bind to the internal ribosome entry site (IRES) of the viral RNA, preventing initiation of translation. New inhibitors were proposed based on the reported X-ray crystal structure of the parent compound bound to the IRES. Utilizing the classic Gabriel synthesis and reductive amination, new alkylamino side chains were produced and introduced late into the synthetic route via a nucleophilic aromatic substitution reaction. The target molecules will then be made available to collaborators for bioassay and continuing refinement of side chain substituents. This refinement is expected to lead to improved binding affinity and selectivity.
Listed skills include Organic Synthesis, Chemistry, Organic Chemistry, Hplc, and 19 others.
Scott Burley's current company
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Scott Burley work experience
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Account Manager
Current
Associate Scientist I
Research Associate
Scientific Technician
Cellarman Ii
Graduate Research Assistant
Successfully completed my Master's Degree in Organic Chemistry while working on two research products:Diversity-Optimized Route to the Ergoline Skeleton• Developed a new route to the ergoline skeleton that does not require prior functionalization of the indole 4-position. • Applied a 9-step process including a Fischer indole synthesis, several indole protections and deprotections and a palladium assisted intramolecular cyclization to construct the lysergic acid backbone in a novel fashion. • Introduced indole moiety late in synthesis to allow for late stage introduction of a variety of substituents to that region. • Operated preparative HPLC for purification of desired small molecules and LC/GC-MS to monitor the formation of desired compounds. • Utilized NMR methods including 1H, 13C and COSY to determine structure of new compounds.The Efficient Synthesis of New Hepatitis-C Viral Inhibitors• Completed synthesis of dihydropyranobenzimidazole derivatives for new HCV inhibition drugs. • Designed a late stage derivitization route to incorporate new alkyl amino side chains into an exsisting 10-step total synthesis. • Obtained a crystal structure of an inhibitor bound to the IRES of the viral RNA. The crystal structured allowed for the design of new alkyl amino side chains to enhance binding affinity and to improve on viral inhibition.• Designed a general route to synthesize new alkyl amino side chains via the Gabriel synthesis.
Chemistry Teaching Assistant
Provide lecture, assistance and motivation to students to succeed. Demonstrate proper technique for lab skills and safety protocol for lab environment.
Service Technician
Responsible for fire extinguisher maintenance and inspections for a variety of small business and public centers. Fire extinguishers were inspected, serviced and gas regulated.
Colleagues at Chemglass Life Sciences
Other employees you can reach at cglifesciences.com. View company contacts for 115 employees →
Nicholas Camacho
Colleague at Chemglass Life SciencesWilliamstown, New Jersey, United States
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Ilan Labelle Aviram
Colleague at Chemglass Life SciencesEncinitas, California, United States
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Morgan Eaton
Colleague at Chemglass Life SciencesGreater Indianapolis, United States
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Caitlin Douglas
Colleague at Chemglass Life SciencesGreater Philadelphia, United States
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Lyangela Cardona
Colleague at Chemglass Life SciencesVineland, New Jersey, United States
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Kayla Randazzo
Colleague at Chemglass Life SciencesHammonton, New Jersey, United States
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Johanna Diaz
Colleague at Chemglass Life SciencesGreater Philadelphia, United States
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Christine Cotter
Colleague at Chemglass Life SciencesGreater Philadelphia, United States
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Quonte W.
Colleague at Chemglass Life SciencesVineland, New Jersey, United States
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Destiny Shelton
Colleague at Chemglass Life SciencesVineland, New Jersey, United States
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Scott Burley education
Master Of Science (M.S.), Synthetic Organic Chemistry - Natural Products
Bachelors Of Science, Acs Chemistry
Frequently asked questions about Scott Burley
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What company does Scott Burley work for?
Scott Burley works for Chemglass Life Sciences.
What is Scott Burley's role at Chemglass Life Sciences?
Scott Burley is listed as Account Manager at Chemglass Life Sciences Covering Southern California, Arizona and Colorado at Chemglass Life Sciences.
What is Scott Burley's email address?
AeroLeads has found 1 work email signal at @cglifesciences.com for Scott Burley at Chemglass Life Sciences.
Where is Scott Burley based?
Scott Burley is based in San Diego, California, United States while working with Chemglass Life Sciences.
What companies has Scott Burley worked for?
Scott Burley has worked for Chemglass Life Sciences, Genomics Institute Of The Novartis Research Foundation, Dart Neuroscience Llc, Genentech, and Lagunitas Brewing Co.
Who are Scott Burley's colleagues at Chemglass Life Sciences?
Scott Burley's colleagues at Chemglass Life Sciences include Nicholas Camacho, Ilan Labelle Aviram, Morgan Eaton, Caitlin Douglas, and Lyangela Cardona.
How can I contact Scott Burley?
You can use AeroLeads to view verified contact signals for Scott Burley at Chemglass Life Sciences, including work email, phone, and LinkedIn data when available.
What schools did Scott Burley attend?
Scott Burley holds Master Of Science (M.S.), Synthetic Organic Chemistry - Natural Products from San Diego State University.
What skills is Scott Burley known for?
Scott Burley is listed with skills including Organic Synthesis, Chemistry, Organic Chemistry, Hplc, Public Speaking, Synthetic Organic Chemistry, Nmr Spectroscopy, and Microsoft Office.
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