Cale Crowder Email & Phone Number

Albuquerque, New Mexico, United States

Albuquerque, New Mexico, United States

• Characterized the presence of goal and state signals in human intracortical microelectrode arrays recordings• Designed statistical methods to analyze force tuning in neurons• Updated existing recording hardware/software to increase the number of recording electrodes by 100%• Created a state-of-the-art reinforcement learning controller for a functional electrical stimulation system• Created a method to optimize brain computer interface feature extraction for non-linear decoders• Designed experiments to investigate the presence of motor manifolds in the motor cortex• Applied linear system identification to brain computer interface signals• Prototyped proportional-integral-derivative controllers for controlling human arms using functional electrical stimulation

• Managed laboratory personnel during adviser’s year-long sabbatical in South Korea• Characterized toxicities and transfection efficacies of linear poly(ethylene) imine (LPEI) β-galactosidase pDNA conjugates for delivery via L-tyrosine polyphosphate (LTP) nanoparticles• Suppressed cellular pump ATP7B in HepG2 cells using shRNA encapsulated in polymeric nanoparticles functionalized with folate for the purpose of limiting heavy-metal-based drug resistance in cancer cells• Synthesized and completed in vitro characterization of novel hyaluronic acid-polyphenolic drug conjugates as anti-cancer agents• Characterized transitional blood flow in a model of straight vascular macrostructures under physiological conditions• Developed VEGFR2 genetic therapeutics for the treatment of preeclampsia• Investigated hyaluronan-based drug coatings for microneedle patches used in treating melanoma• Adapted microfluidic methods to characterize bacteria-targeting nanoparticles

Akron, Ohio

• Instructed senior-level biomedical engineering undergraduates in a small-group laboratory environment• Prepared laboratory reagents for instructional work• Developed methods and written protocols for new techniques designed to improve the existing curriculum

Pittsbugh, Pa

• Designed linear discriminant analysis classifiers to detect changes in neural tuning as human research participants used intracortical brain-computer interfaces to move robotic arms towards objects

Rootstown, Ohio

• Automated detection and counting of immunohistochemically-labelled organelles inconfocal micrographs of cardiac myocytes

Rootstown, Ohio

• Investigated the in vitro and in vivo osteogenic properties of human reamer-irrigator-aspirator wastewater• Characterized changes in protein expression and ossification in mice as a result of induced traumatic brain injury• Characterized primary osteoblasts and mesenchymal stem cells derived from transgenic mice• Developed capacitively-coupled electrical stimulation chambers for increased endochondral ossification in preadolescent mouse femurs in organ culture• Characterized the osteoconductive properties of spin-coated polymer substrates

Seattle Washington

• Performed immunohistochemical staining and computer-automated image characterization of acute vascular damage caused by single-shank neural implants in the rat motor cortex

Doctor Of Philosophy (Phd), Biomedical Engineering

Bachelor Of Science (B.S.), Biomedical Engineering - Specializing In Biomaterials And Tissue Engineering

Activities and Societies: Biomedical Engineering Society National Residence Hall Honorary Sigma Lambda Honorary