Caleb Akers Email & Phone Number

Florence, Ky, Us

Cincinnati, Ohio, United States

Manage and provide accountability for day-to-day operations of the project, as defined by the contract and according to ICH/GCP and all other applicable laws, rules, and regulations. Serve as primary Sponsor contact for operational project-specific issues and study deliverables. Maintain in-depth knowledge of protocol, therapeutic area and study deliverables. Provide cross-functional oversight of internal project team members and deliverables, which includes ensuring all necessary project-specific training is provided. Review and provide input for study protocol, edit check specifications, data analysis plan, and final study report, when applicable. Develop operational project plans. Manage risk assessment and execution. Responsible for management of study vendors. Manage site quality, including direct supervision of project Clinical Research Associates and monitoring deliverables.

• Designed and investigated ternary polymer nanoparticles for their use as gene delivery vehicles, with the goal of investigating the effect of charge on particle uptake and gene delivery efficiency• Developed folate-targeted polymer nanoparticles for improved nucleic acid delivery and transfection efficiency to cancer cells• Designed low throughput endocytic knockdown screens using both small molecule inhibitors and siRNA knockdown to investigate the uptake pathways of various polymeric delivery vectors

Greencastle, In

Greencastle, In

• Designed a dual-drug delivery mechanism using gold nanoparticles for time-controlled release of therapeutics in the treatment of lung cancer.• Assessed delivery efficiency and release mechanics using fluorophore analogs in the development of a novel cancer treatment

Baltimore, Maryland

• Generated and processed preliminary data on the effects of hyperthermia on SKBR-3 breast cancer cells to compare these results to iron oxide nanoparticle hyperthermia treatment

Greencastle, In

• Developed an experimental setup to image droplet interfaces at high speed to investigate the forces responsible for the noncoalescence phenomenon• Generated and processed large data sets using high speed imaging and Image J for the investigation of noncoalescence• Programmed macros in Excel to expedite data processing for myself and later students in the study of high-speed images

Doctor Of Philosophy - Phd, Pharmaceutical Sciences

Bachelor Of Arts (Ba), Physics, Biochemistry, 3.795/4.00

Activities and Societies: Society of Physics Students; Sigma Pi Sigma; Sigma Nu Beta Beta Chapter; National Society of Collegiate.