Cari Meisel Email & Phone Number

Cambridge, Ma, Us

• Design and manufacturing of novel biocompatible coatings for laser particles, including development of assays and analytical techniques to characterize physical, chemical, and functional properties of microparticle surfaces.• Pilot-scale manufacturing and manufacturing scale-up, as well as establishment of quality control procedures for testing of biocompatible coatings, including the development and maintenance of technical documentation for laser particle manufacturing processes.

Greater Boston Area

Board Member in charge of logistics- Founding member of the studio/business- Manage studio instructors and staff, ~20 total people- Direct studio functions day-to-day, including planning and scheduling of classes, workshops, events, and meetings- Instrumental in creating and enacting studio/business vision and direction

Greater Boston Area

• Spearheaded adaptation of oncology-targeted antibody drug conjugate technology from an academic environment to a translational-focused setting, including process development, assay development, and implementation of GLP compliance practices.• Developed company scientific strategy and direction in a fast-paced biotech start-up environment focused on a novel antibody drug conjugate for oncological and immunotherapy applications.• Managed and coordinated projects and studies with CROs and C(D)MOs, including scientific due diligence, technology transfer, protocol and assay development, data sharing, and data analysis of both in vitro and in vivo projects.• Presented deliverables to stakeholders including company investors and board members, as well as delivering scientific presentations to both internal and external audiences. • Supervised and managed interns, including laboratory skills training, project development and feedback, setting timelines/goals for deliverables, and mentorship.• Excellent written and verbal communication skills, including grant writing, report writing, manuscript writing, and presentations for both scientific and general audiences such as company investors and board members.• Selected as an NIH reviewer for the CBD SBIR/STTR grant section July 2023; ongoing.

Boston, Massachusetts, United States

• Spearheaded adaptation of technology from an academic environment to a translational-focused setting, including process development, assay development, and implementation of documentation/compliance practices• Responsible for overseeing, designing, and executing in-house experiments and protocols, including chemical conjugation, in vitro characterization, histology, immunofluorescence, and assay development• Responsible for setting up and managing company lab space and resources in shared biotech incubator

Greater Boston Area

Department: Biomedical Engineering and Biomolecular PharmacologyAdvisor: Joyce Wong, Ph.D. Thesis title: Superparamagnetic Iron Oxide Nanoparticles for Early Detection of Calcific Aortic Valve DiseaseGrants/Fellowships:- Distinguished BME Fellowship, Boston University (9/2013 - 9/2014)- Biomolecular Pharmacology Training Grant, NIGMS (9/2014 - 9/2015)- Inflammatory Disorders Training Program, NIH (9/2015 - 9/2017)- Pre-doctoral training in Cardiovascular Biology, NIH (9/2017 - present)

Greater Philadelphia Area

Division: Vaccine Manufacturing, Science, and Commercialization- Member of the Emerging Markets Vaccine Process Development group working on the RotaTeq® vaccine- Optimization of vaccine production and purification process at the bench scale and subsequent scale-up to full production scale, including experimentation as well as authoring relevant documentation- Conceive and develop new characterization and assay methods to better understand process changes, including protein purification methods as well as Western blotting, ELISA, SDS-PAGE, etc.- Courses: Immunology, Practical Statistics, Design of Experiments, Fluorescent/Spectroscopic Methods, Lean Six Sigma Yellow Belt Training- Awards: Poster presentation award for Best Use of Science and Technology for characterization work

Philadelphia

Senior design project: Development of a Real-Time Sensing Platform for Directed Evolution- Developed and carried out a method for producing chromophore-linked proteins, both synthetically-derived as well as biologically-derived- Used chromophore-linked proteins as well as Forster resonance energy transfer (FRET) to optimize the selection step of the ribosome display procedure by quantifying protein-binding interactions in real time

Greater Philadelphia Area

- Synthesized versions of hyaluronic acid modified to be hydrolytically degradable and photocrosslinkable - Electrospun scaffolds from modified hyaluronic acid polymer- Designed experiments to test scaffold properties in areas of degradation, mechanics, and cell-scaffold interactions- Developed and executed methods for analyzing results of the experiments listed above

Cleveland/Akron, Ohio Area

- Conducted research in Cystic Fibrosis, performing genetic groundwork to create a new mouse model- Designed a method of incorporating a tri-reporter protein into the mouse genome to create a Cftr knock-out model- Constructed the important surrounding regions of the mouse chromosome in vitro

Doctor Of Philosophy - Phd, Bioengineering And Biomedical Engineering

Activities and Societies: GWISEDepartment: Biomedical Engineering and Biomolecular Pharmacology Advisor: Joyce Wong, Ph.D. Teaching.

Master'S Degree, Bioengineering And Biomedical Engineering

Activities and Societies: GWISE

Bachelor Of Science - Bs, Bioengineering And Biomedical Engineering, 3.83

Activities and Societies: Relay for Life, Chi Omega, West Philly Swingers Dance Troupe