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I am a Senior Scientist who transitioned from the R&D department to Process Development at HebeCell over the last 4 years. HebeCell Corp develops a manufacturing platform to generate Stem Cell derived NK cells. The small nature of HebeCell gave me the opportunity to be involved in R&D, Process Development, Assay Development, Clean Room Manufacturing and document writing to file for IND. This position taught me about all the components which are required to get a cell therapy product form R&D to the clinic. Additionally, I received a PhD in Neuroimmunology from Memorial Sloan Kettering Cancer Center in collaboration with the University Freiburg in Germany. My PhD work concerned a neurodegenerative mouse model with a particular interest in microglia and their interaction with other neuronal cell types. Additionally, during my master thesis work I also collected great experience in vitro cell systems in the field of Cardioimmunology.
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Consultant BioanalyticTolerance BioCambridge, Ma, Us
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Senior ScientistHebecell Corp Jun 2021Natick, Massachusetts, UsIn my role as a Senior Scientist at HebeCell Corp, I led various analytical development projects, including qPCR tests, cytotoxicity assessments, and viral clearance testing for cell therapy products. I designed GMP testing strategies, authored SOPs, and implemented cryopreservation techniques for cells in bags. Additionally, I established final drug product formulations and shipping strategies for live drug products and tested different iPSC and ES cells with and without CAR constructs in the NK differentiation platform. -
ScientistHebecell Corp Mar 2021 - Jun 2021Natick, Massachusetts, UsGeneration of iPSC derived CAR-NK cells
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Phd StudentMemorial Sloan Kettering Cancer Center Mar 2017 - Jan 2021New York, Ny, UsPhD in Neuro-Immunology in Frederic Geissmann's Lab in collaboration with Marco Prinz at the University Freiburg. My PhD work is concerning a mouse model in which a somatic mutation is introduced into the tissue resident macrophage linage targeting specifically the microglia in the brain and causes a form of neurodegeneration (Mass et al 2017 Nature). I am analyzing the clonal expansion of mutated microglia and their effect in different parts of the brain by flow cytrometry, cell sorting, ddPCR and histology.Additionally, I am testing a combination treatment to improve the disease progression and survival time. -
Research Internship And Master ThesisHeidelberg University Hospital Mar 2015 - Jun 2016Master thesis in the Cardiology Department with Dr. Florian Leuschner to establish and perform a cell-based compound screen in the context of myocardial infarction healing particular concerning the WNT pathway. I worked with cell culture and different cell stimulations including hypoxia, luciferase assays, qPCR and western blots.
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Research InternshipHarvard University May 2014 - Oct 2014Cambridge, Massachusetts, UsResearch internship for 6 months in Vlad Denic' Lab. The aim was to investigation of the influence of autophagy in meiosis in the model organism yeast. Therefore, I generated different yeast knock out lines and performed microscopy. -
Research InternshipDkfz - German Cancer Research Center Feb 2014 - Mar 2014Heidelberg, DeResearch Internship under the supervision of Dr. Joel Beaudouin who is part of Eils Lab. With the help of live cell imaging and fluorescent correlation microscopy a dominant negative effect of a CD95 receptor (death domain receptor) was investigated. -
Bachelor ThesisDkfz - German Cancer Research Center Apr 2013 - Jul 2013Heidelberg, DeBachelor thesis in Thomas Hofmann's Lab for 3 months. I was looking at the interaction between the tumorsuppresor protein HIPK2 and a cell cycle regulator Plk1. Therefore techniques of immunoprecipitation and microscopy was used.
Carina Meyer Skills
Carina Meyer Education Details
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The University Of FreiburgImmunology -
Heidelberg UniversityMolecular Biotechnology
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Heidelberg UniversityMolecular Biotechnology
Frequently Asked Questions about Carina Meyer
What company does Carina Meyer work for?
Carina Meyer works for Tolerance Bio
What is Carina Meyer's role at the current company?
Carina Meyer's current role is Consultant Bioanalytic.
What is Carina Meyer's email address?
Carina Meyer's email address is ca****@****berg.de
What schools did Carina Meyer attend?
Carina Meyer attended The University Of Freiburg, Heidelberg University, Heidelberg University.
What are some of Carina Meyer's interests?
Carina Meyer has interest in Science And Technology.
What skills is Carina Meyer known for?
Carina Meyer has skills like Cell Biology, Yeast, Molecular Biology, Research, Cell Culture, Biotechnology, Microsoft Office, Powerpoint, Fluorescence Microscopy, Fcs, Imagej, Confocal Microscopy.
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