Carla Matos Email and Phone Number

• Responsible for providing relevant medical insights during Brand Team Meetings and collaborating with the Marketing team/Product Manager in the development of local Repatha Brand Plan for 2022/23;• Responsible for identify and select the relevant & strategic research sites for new cardiovascular studies along with local Clinical Study Manager ( CVOT and other studies related to Dyslipidemia including Lpa);• Providing Medical expertise for Health Economic (HE)/Market Access team in the construction of the product dossier for submission to local HE Authorities;• Responsible for organization and Implementation of trainings to commercial team using different channels of communication, including Workshop of new entrants/21;• Responsible for organization and execution of Lipid Courses and/or Preceptorships at highly recommended institutions increasing specialists in dyslipidemia nationwide ;• Responsible for coordination the execution of ACC Cascading Events in strategic Institutions nationwide reaching more than 1000 HCPs;• Organization of an innovative and successful model of Preceptorship uniting two therapeutic areas (Bone & Lipids) bringing high level discussions among endocrinologists and other specialties;• Execution of Briefings and Engagement of KOLs for Promo or Non-Promo Events;• Reviews and approvals of MKT, Market Access and PSP materials in a timely manner; • Support execution /organization of Speaker Training Meeting, as well as responsible by the development of supportive promotional materials such as Master Slide deck;• Engagenment of Medical Societies ( SBEM, SBC, SOCESP etc).

• Educate and communicate clinical value, outcomes, and economic data to payers, providers, key stakeholders, advocacy, and access enablers• Respond to unsolicited inquiries consistent with the MSL compliance standards• Support cross-functionals teams , e.g. , MKT, Value & Access and Clinical Trials as required and according to the Company strategy ; • Provide and/or present field observations and insights to internal stakeholders;• Execute scientific engagement plan according to annual MSL goals and metrics• Develop and implement local OL plans in line with scientific engagement plan• Support Amgen sponsored research and liaise with potential investigators in non-sponsored clinical research• Lead and/or participate on project teams that support MSL strategies and tactics as delegated by MSL leadership• Providing trainings for the sales force and other Company departments as well as MSL presentations in important Institutions;• Responsible for organization and execution of Lipid Courses and/or Preceptorships at highly recommended institutions increasing specialists in dyslipidemia nationwide ;• Repatha Captain for Intercontinental Countries

Diverse therapeutic areas:-Reviews/approves and provides inputs and guidance on contents in non-promotional, promotional and VA&P materials according to SOPs and local requirements ; -Scientific support in educational events and/or Congresses;-Support and collaborate widely in the launch of new products.

• Perform monthly review of key performance indicators indicating opportunities for improvement and corrective actions to ensure compliance with Headquarters and Regulatory Authorities;• Perform and coordinate internal quality audits related to PV activities;• Coordinate the Safety Operations, ensuring compliance of related processes;• Coordinate the Signal Detection process for local products, following local RA requirements and company procedures;• Manage the aggregate reports (PSUR/PBRER), ensuring that they are developed appropriately and submitted to HA as per local regulations; • Responsible for Safety Clinical Trials oversight in LATAM countries ( Peru, Argentina, Chile and Colombia);• Coordinate the Pharmacovigilance Agreements in local commercial contracts;• Perform oversight of the Service Providers in PV activities• Support local team

• Local QPPV;• Perform monthly review of key performance indicators indicating opportunities for improvement and corrective actions to ensure compliance with Headquarters and Regulatory Authorities;• Coordinate the Safety Operations, ensuring compliance of related processes;• Manage the aggregate reports (PSUR/PBRER), ensuring that they are developed appropriately and submitted to HA as per local regulations;• Responsible for Safety Post Marketing oversight in LATAM countries ( Peru, Mexico and Venezuela);• Generates/Approves/Distributes Regional and Country Specific SOPs;• Coordinate the Pharmacovigilance Agreements in local commercial contracts;• Perform oversight of the Service Providers in PV activities;• Implementation of RMP activities at local level;• Responsible for the local Customer Service activities;• Support and Manage the local team

Launching cosmeceutical lines in the American Aesthetic Market. Management of Events (Les Nouvelles Estetiques, Spa Management, American Academy of Dermatology, Plastic Surgery Events and Workshops (Miami & NY). Management of trainings for healthcare professionals and relationship improvement with the Opinion Leaders (scientific approach). Support and Manage the local team including Customer Service Area . Budget Development.

Created marketing tools and specific approaches for launching new professional products. Responsible Person for Safety Reports to the Manufactures. Assists the Customer Relationship Area related to pharmaceutical/medical information. Responsible Person for scientific training and relationship with the Opinion Leaders (Dermatology/Plastic Surgery and Aesthetic Medicine-Nationwide).

Responsible for Scientific support to physicians, others healthcare professionals and company staff related to Medical Information, participation in the Medical Congresses promoting the scientific information services and development of marketing strategies and reviewed promotional materials in Dermatology and Gynecology Markets.

Microspheres and liposomes in the study of controlled release proteins- design involving the development and improvement of a general process of vaccines : 1. the formation of biodegradable microspheres for the controlled release of vaccines and 2. The use of liposomes as carriers for immunogens and / or adjuvants in vaccines. Intensive participation in scientific congresses , including several scientific publications on the local and international magazines.