Carla S.

Carla S. Email and Phone Number

Carla S.'s Location
Rio de Janeiro, Brazil, Brazil
About Carla S.

Biomarker Development with demonstrated experience in Immunology preclinical and clinical phase projects. Development and implementation of biomarkers to foster science and data-driven decision making.I specialize in DNA identification systems, especially in the use of next-generation sequencing (NGS) platforms. In my current work, I use NGS platforms for the characterization of biopharmaceutical candidates, including viral vectors for gene therapy and cell lines. In my previous roles, I had the experience of using NGS technology for product authentication and the diagnosis of viral pathogens. I also develop real-time PCR assays through genome skimming and comparative genomics. In addition to laboratory experience, I also have practical knowledge of building genome assemblies and analyzing genomes using various bioinformatics tools.

Carla S.'s Current Company Details

Carla S. Work Experience Details
  • Genentech
    Senior Principal Scientist - Translational Biology & Bioanalytical
    Genentech Sep 2022 - Jan 2023
    Boston, Massachusetts, Estados Unidos
    - Led the development, validation, and transfer of GLP NAb assays to CROs for AAV based gene therapies - Produced data package for PK/PD modeling that included cell binding, receptor occupancy & internalization kinetics- Provided support for pre-IND studies in both rare disease and autoimmune disease related programs- Trained Scientists on dPCR/ddPCR instruments, developed protocols for routine viral titer assessments - Investigated the presence of antigen specific T-cells subsets in PBMCs of ImmTOR treated clinical samples - Other responsibilities include MSD ELISA assays, cell culture, documentation and CRO communications-
  • Genentech
    Scientist Ii - Ngs And Biomarker Development
    Genentech Jul 2021 - Sep 2022
    Boston, Massachusetts, Estados Unidos
  • Roche
    Diagnostic Analyst
    Roche Oct 2018 - Jul 2021
  • Bio-Manguinhos / Fiocruz
    Diagnostic Analyst
    Bio-Manguinhos / Fiocruz Jan 2021 - Jun 2021
    Rio De Janeiro, Brasil
  • Universidade Federal Do Rio De Janeiro
    Scientific Researcher
    Universidade Federal Do Rio De Janeiro Feb 2010 - Sep 2018

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