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A PhD scientist with several years of laboratory experience in the pharmaceutical industry, my primary focus is small molecule drug metabolism structural ID and quantitation studies in both pharmaceutical discovery and development. I currently serve as the Oncology Lead (Manager) within Biotransformation at Pfizer.I am detail-oriented and highly organized, able to manage multiple projects simultaneously and communicate effectively at all levels within an organization. An active contributor to the ADME/Biotransformation scientific community, I am a member of ISSX, in which I serve in the Biotransformation Mechanisms and Pathways Steering Committee.I value fostering diversity and inclusion in the workplace. I strive to create an environment where individuals can bring their authentic and best selves to work while feeling happy and supported.
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Principal ScientistPfizer Nov 2021 - PresentNew York, New York, UsOncology Lead in Small Molecule Biotransformation (Drug Discovery and Development) -
Senior ScientistPfizer Aug 2019 - Nov 2021New York, New York, UsBiotransformation and Structural Elucidation
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Phd Candidate In Pharmacology And Molecular SciencesJohns Hopkins University Aug 2014 - Jul 2019NSF Graduate FellowMy work focused on exploring the interplay between cytochrome P450 drug metabolism and hepatotoxicity mechanisms of drugs used to treat HIV- specifically non-nucleoside reverse transcriptase inhibitors. I employed a myriad of techniques, including: microsomal drug metabolism assays, primary hepatocyte culture, mouse dosing and dissection, bright-field and fluorescent microscopy, western blotting, PCR, targeted LC-MS/MS detection of drug metabolites, and LC-MS proteomics.
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Research Intern, Pharmacokinetics And Drug MetabolismAmgen Jun 2017 - Sep 2017Thousand Oaks, Ca, Us-SimCyp in silico drug clearance modeling-Development of an in vitro active hepatic drug uptake assay-LC-MS/MS relative quantitation of small molecules-Cryopreserved hepatocyte culture-Data collection, management, analysis, and presentation -
Research InternUsamriid , Us Army Medical Research Institute Of Infectious Diseases Jun 2013 - May 2014Frederick, Maryland, Us- Peptide microarray printing- Surface plasmon resonance binding analysis- MALDI-TOF imaging mass spectrometry analysis of printed peptide microarrays- Fluorescence peptide microarray assay development - Absorbance based enzyme activity assays- Small molecule inhibitor screening- Data collection, management, analysis, and presentation -
Undergraduate ResearcherShippensburg University Of Pennsylvania Oct 2012 - May 2014Shippensburg, Pa, Us- Data collection, management, analysis, and presentation- Training of fellow undergraduate students in laboratory methods- Cloning- Transfection- qPCR- Cell culture (COS7 and SNB19 cell lines)- Immunofluorescent staining- Fluorescence microscopy
Carley Heck Education Details
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Johns Hopkins School Of MedicinePharmacology And Molecular Sciences -
Shippensburg University Of PennsylvaniaBiotechnology Focus
Frequently Asked Questions about Carley Heck
What company does Carley Heck work for?
Carley Heck works for Pfizer
What is Carley Heck's role at the current company?
Carley Heck's current role is Principal Scientist at Pfizer.
What is Carley Heck's email address?
Carley Heck's email address is ca****@****zer.com
What is Carley Heck's direct phone number?
Carley Heck's direct phone number is +126751*****
What schools did Carley Heck attend?
Carley Heck attended Johns Hopkins School Of Medicine, Shippensburg University Of Pennsylvania.
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