Chris Butt Email & Phone Number

Boulder, CO, US

West Lafayette, IN, US

• Interface with customers at the CEO, CSO, VP, and director levels producing >$800K in revenue in the first year of business, 25% YOY growth in year 2, and 100% YOY growth in year 3
• Provide full-spectrum science as a service, aligning with partners to move small molecules, biologics, and antisense oligonucleotides through drug development
• Oversee >100 immunity/inflammation, gut, bone, surgical, and neuroscience models as a member of the IACUC

Boulder, CO, US

• Contribute to the strategic decision to merge Bolder BioPATH with Inotiv resulting in increased company valuation and IND-enabling capabilities
• Drive the development of >25 non-clinical models in <18 months, including Parkinson’s, Alzheimer’s, TBI, Fragile X, epilepsy, cognition, anxiety, and depression

Heerlen, Limburg, NL

• Lead non-clinical strategy, international KOL and CRO networks, and the implementation of new technologies necessary for the support of multimillion-dollar commercial products and medical devices
• Coordinate ~$2M of R&D resources, champion ideas, and future-proof internal and external capabilities in the nervous, immune, bone, and gut systems

Heerlen, Limburg, NL

• Re-design laboratories and negotiate leases to reduce costs by $2M over 5 years
• Right-size the Boulder site as part of Martek’s integration into DSM
• Manage facility operations, personnel safety, DEA licensure and reduced greenhouse gas emissions through recycling/composting and energy savings programs

Heerlen, Limburg, NL

• Connect R&D to alliance partner needs by enabling joint development agreements that result in up to 50% cost sharing on business research projects
• Organize and author international, strategic documents that combine regulatory and scientific expertise to demonstrate the safety and efficacy of company products
• Enhance clinical trial success by merging quantitative proteomics with mini-organ technologies in a $250K project to assess genetic influences on biomarker responses
• Lead a 5-person, global team (US, EU and APAC) that includes clinical scientists
• Deliver timely data that save the company over $1M per project
• Obtained GCP certification (Barnett International training course, 2019)

Heerlen, Limburg, NL

• Lead the de-risking of R&D by developing computer modeling (i.e. in silico screening) and finding novel biomarker responses that result in patentable line extensions
• Manage the U.S. preclinical laboratory reporting to the Global Head of R&D

Heerlen, Limburg, NL

• Carry small molecule application development from discovery to preclinical efficacy, through stage-gate review, and translate findings to clinical studies
• Manage the U.S. preclinical laboratory reporting to Switzerland in a matrixed hierarchy
• Delivered findings at 1 press conference and 17 international conferences
• 2 granted patents, 5 patent applications, 2 book chapters and 12 publications

• Manage neuroscience resources (~$1.2M), report to the Chief Scientific Officer, and move functional lipids and sugars through the stage-gate approvals of product development
• Assess the IP and scientific capabilities of potential acquisitions
• Plan and coordinate the building of a laboratory (~$200K), its capital acquisitions (~$500K), and the hiring of 6 employees with a focus on diversity, equity, and inclusion
• Represent and successfully integrate the group during Martek’s acquisition by DSM

Lewisburg, West Virginia, US

• Test a medical device that correlates oral toxins with chronic diseases, obtain IRB approval and HIPAA certification, and manage 1 medical resident
• Principal Investigator for 4 funded projects that begin at the genome, center on receptor function, and translate to in vivo testing of therapeutics for nicotine and alcohol abuse
• Organize 6 faculty members and teach the 36-hour Medical Neuroscience curriculum for 200 first-year medical students
• Chair the Nervous System curriculum for second-year medical students and coordinate 3 visiting lecturers and 9 clinical and preclinical faculty members
• Trained and managed 9 work-study students and 2 research assistants
• Delivered 2 peer-reviewed publications and 5 international presentations

Boulder, Colorado, US

NIH-funded projects centered on the pharmacogenetics, neurochemistry, and behavior related to the interactions between nicotine and alcohol.

Provided scientific oversight on a protocol for the production of a vaccine through a fermentation method.

Contributed to the building of a statistical model that correlated the chemical profiles of samples, as determined by gas chromatography/mass spectrometry (GC/MS), with the locations of the samples’ origins.

Lexington, KY, US

NIH-funded projects centered on the role of cholinergic receptor subtypes in the wiring of the retina to the brain during development.

Coordinated with a large group of physicians and nurses to ensure that surgical supplies and instruments were available for orthopedic, laproscopic, eye, and plastic surgeries

B.Sc., Biology W/ Chemistry Minor

Ph.D., Neurobiology

Postdoctoral Fellow, Neurochemistry, Pharmacogenetics And Addiction-Related Behavior