Celia Raimondi Email & Phone Number

Cambridge, Gb

Cambridge, England, United Kingdom

Cambridge, England, United Kingdom

• Product development – Technical lead - Reagent developmentDirecting collaborative efforts with CROs to facilitate the development of formulations towards freeze-drying and conduct stability studies. Collaborating closely with Science and Technology Directors to strategize the most effective product development approach. Optimising reagent stability and performance.• Technology development – Technical lead - Ligation/DNA assemblyGuiding the advancement of on-chip DNA assembly (ligation, transport and hybridisation of DNA on-chip), employing strategic thinking to unify engineering, biophysics, and molecular biology for seamless integration and progress. Collaborating closely with the Chief Technology Officer and Technology Director to determine technical risks and devise the most effective strategy for mitigation. Developing and performing multi-step sensitive assays spanning from on-chip to in vitro to propel the advance the DNA ligation and hybridisation processes.Leading a team scientists to generate pertinent data on-chip and in vitro.Writing several disclosures to provide technical solutions.

Leading the Parkinson drug discovery project of the C. elegans platform. Managing small team of scientists to develop a robust pipeline to test new small molecules using C. elegans, worm tracker, Leica microscopy. Develop automation protocol to increase the robustness and the throughput of the pipeline. Coordination with chemists and data analysists to extract the most information from the data. Internal and external presentation of the data.

Cambridgeshire, England, United Kingdom

Cambridge, Angleterre, Royaume-Uni

I designed a pipeline that uncovered 49 new ageing genes. I developed high throughput semi-automated molecular and cellular assays to characterise the ageing candidates. I designed and optimised a semi-automated fluorescence assay from the worm preparation to the analysis script to determine the effect of the new ageing candidates. I developed molecular screening assays using microfluidics and RNA-seq to classify the ageing genes.Passionate for data analysis, I developed uncommon analysis to extract the most information out of the data.

I analysed the interplay between the replication and epigenetics using the fission yeast. I determine the role of the histone demethylase 1 (Lsd1) at the replication pause site: MPS1 by developing a sensitive molecular biology assay to quantify the intermediate of replication.

Paris, Île-De-France, France

I designed, lead and realised the project. I developed and optimised molecular biology assays and high throughput assays such as whole genome NGS sequencing and ChIP-sequencing to determine the spatial organisation of the proteins involved in the asymmetric cell division of the fission yeast. I developed uncommon computational pipeline to analyse NGS data and I determine the sequencing signature of a natural and persistent single strand break.

Doctor Of Philosophy - Phd, Molecular Genetics

Master'S Degree, Genetics

Licence, Biology, General