Summary. Lifted Testing Labs is certified by the state of Rhode Island to test cannabis raw material, concentrates and infused products such as edibles, non-edibles, and pre-rolls for Potency, Pesticides, Heavy Metals, Microbials, Water Activity, Residual Solvents, and Terpenes. Lifted Testing Labs offers full panel testing for all compliance requirements and mandates, as well as support in the developing of new products.Responsibilities. Direction of all method development, validation and qualification activities, in accordance with corporate, customer and regulatory guidelines. Daily management of personnel and departmental activities. Supervision of all personnel in the laboratory and for hiring adequately trained personnel. Scientific and technical guidance to internal teams and clients.Specifics. PerkinElmer QSight 420 • PerkinElmer NexIon 300D • Flexar • Agilent 7694 Headspace • Agilent 5973 Mass Spectrometer • Agilent 66890N Network GC System • Simplicity 3Q • Syngistix • TotalChrom • Mass Hunter.

My current interest centers in the mechanistic understanding of relevant biological phenomena at the molecular level. I use mass spectrometry and biophysical chemistry to investigate the role of environmental toxins in epigenetics, the function of transport proteins in neurodegenerative diseases, and the conformational changes and reversibility of proteins in ammonium ionic liquids.

Summary. This academic position allows me to impart lectures and laboratory training in different fields of Chemistry and Life Sciences. I also help my students to prepare their transition from university to industry, introducing them into SOP, GLP, GMP and other fundamental knowledge required in their future scientific endeavors. During this time at TAMU-CC I have scored an average of 4.65/5.00 in my Students Course Evaluations.

Summary: Contract research organization specialized in early phase clinical pharmacology, biological characterization methods, and scientific affairs services. The bioanalytical services provided by PRACS included the support of more than 5,000 bioanalytical studies and the analysis of more than 600,000 samples annually. PRACS Institute ceased the entirety of its North American operations abruptly on March 20, 2013.Responsibilities: Direction of all method development and validation activities at PRACS bioanalytical facilities in Toronto and Fargo, in accordance with corporate, customer and regulatory guidelines. Daily management of personnel and departmental activities. Providing scientific and technical guidance to internal teams and clients.Specifics: 9+6 direct reports between principal investigators, validation chemists and quality control specialists • API 4000 • QTRAP 4000 AB Sciex, QTRAP 4500 AB Sciex • QTRAP 5500 AB Sciex, • Quatro Altima Micromass Waters • Agilent 1200 HPLC Pumps with Column oven and Degassers, • Agilent 1100 HPLC Pumps with Column oven and Degassers • CTC PAL Auto samplers, Cohesive auto samplers, waters auto samplers • Analyst 1.5.1 • Masslynx • Watson LIMS 7.4

Summary: Biotechnology contract research organization centered in the area of human health, with pioneering UPLC-MS and UPLC-MSMS biomarker systems for the early diagnosis of liver disease. OWL incorporated MD Renal in 2011. Recently, OWL initiated the validation of LiverTox, a Biomarker System I designed. LiverTox’s patent is in the process of registration.Responsibilities: Direction of research projects and external collaborations with universities, CRO and industry. Design new research projects in accordance with corporate, customer and regulatory guidelines. Budget management. Supervision of departmental personnel (14 direct reports). Representation of the company in technical meetings with clients.Awarded Research Projects:2010-2013. Dendria. Innovative solutions to accelerate the identification and development of drugs in pathologies of the neural systemCENIT Project financed by the Spanish Ministry of Science and Innovation.2010-2013. LiverBiomark. Development of biomarkers for determining the degree of hepatic fibrosis and patient prognosis of acute hepatic diseases using advanced metabolomics toolsINNPACTO Project financed by the Spanish Ministry of Science and Innovation.2010-2012. LiverTox. Software development for the prediction and quantification of hepatotoxicity based on metabolomic profile analysis in serumBIZKAIBERRI DBF Project financed by the Vizcaya Office for Industrial Promotion.2010-2012. AntiLipid. Development of a prototype for the preservation, extraction and diagnosis based on monoclonal antibodies against lipid markers of hepatic disordersETORGAI Project financed by the Basque Department of Technology and Innovation. 2010-2012. BioDetect. New detection techniques for biomarkersETORGAI Project financed by the Basque Department of Technology and Innovation.

Summary: Biotechnology contract research organization centered in the development of innovative bioanalytical and bioinformatics tools oriented to metabolomics. During this time, I produced intellectual property currently being materialized in two patents, one of them concerning the development of a new atmospheric pressure ionization source.Responsibilities: Head of scientific research operations and collaborations. Design and direction of research projects. Definition of timelines for working teams (5 direct reports), collaborators and CROs. Budget management. Staff hiring, training and coordination. Reviewing of SOPs, validation procedures and company reports. Representation of the company at international forums.Awarded Research Projects:2010-2012. MetaboSearch. Informatic tool for the automatic detection and identification of metabolites in biofluidsTORRES QUEVEDO Project financed by the Spanish Ministry of Science and Innovation. 2010-2011. Urine-MS. Design and development of a kit for the experimental optimization of mass spectrometric analysis of urine samplesGAITEK Project financed by the Basque Department of Technology and Innovation. 2009-2011. Metabol. Creation of a mass spectrometric platform for the identification and absolute quantification of metabolites in complex mixturesINNPACTO Project financed by the Spanish Ministry of Science and Innovation.2008-2013. TotalMatch. Design and development of a kit for the identification and absolute quantification of metabolites in complex mixturesNETS Project financed by the Basque Department of Technology and Innovation.

API-Mass Spectrometric Investigations on the Mechanism of Organocatalytic ReactionsDuring my stay at the institute I introduced the use of extractive electrospray ionization EESI to the detection and identification of short-lived intermediates in catalyzed reactions. This novel technology offered the means to validate the catalytic cycle proposed for the organo-catalyzed aldol reaction, recognized as a powerful tool for the construction of new carbon–carbon bonds.Presentation Award at the “Berichtskolloquium zum DFG Schwerpunktprogramm Organokatalyse”, Max Planck Institut für Kohlenforschung, Germany, 2006Title: ESI-MS Study on the Aldol Reaction Catalyzed by L-Proline

Nucleation Kinetic Effect on Amyloid β Protein (βAP) aggregation.I initiated an investigation concerned with Alzheimer’s Disease. My research focused on the interaction of transition metal ions with Amyloid β-protein pre-aggregates. The project was an exploratory overview of the possibility of using MS as tool for the investigation of aggregation processes, establishing a base for more detailed studies of the behaviour of these specific kinds of proteins.The Centre’s commitment to the development of new MS technologies allowed for in-depth examination of the fundamentals of the technique. During my time at York University, my knowledge of MS was enriched through contact with leading professionals in the field, and I was fortunate to witness the design and preliminary studies for the construction of a custom-built ion mobility MS apparatus.