Chandra Patel Email and Phone Number
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Specialties: •Project lead or manager on multiple projects from target identification through final candidate selection •Experienced in preclinical development of cell and gene therapy, biologic and small molecule therapeutics •Significant experience in non-malignant hematology and autoimmune disease•Prepared briefing books and participated in scientific advice meetings with FDA, PEI and MHRA •Experienced team leader, heading labs consisting of PhDs, postdocs and RAs•Alliance manager for multiple academic collaborationsPrevious experience:•Enzymology including mechanism and kinetics•Protein-protein and protein-lipid binding•Rational protein engineering•Mammalian cell culture •Cloning and characterization of protein targets; protein expression using a variety of expression systems•Macromolecular X-ray crystallography and structure determination
Gentibio
View- Website:
- GentiBio.com
- Employees:
- 52
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Co-Founder, Senior Vice President R And D OperationsGentibioSan Mateo, Ca, Us
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Co-Founder, Vice President R&D OperationsGentibio Jun 2020 - PresentCambridge, Massachusetts, Us
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Director Project Management, Autoimmune DiseaseCasebia Therapeutics Oct 2018 - Sep 2019Cambridge, Ma, Us• Drove project core team and nonclinical subteam to a target 2H 2020 IND for IPEX.• Casebia project lead for Seattle Children’s collaboration aimed at completing IND enabling research studies. • Contributed to design and analysis of pivotal in vivo pharmacology studies.• Worked with team members to develop biodistribution and toxicology study designs.• Contributed to the writing of multiple briefing books for scientific advice from FDA, PEI and MHRA.• Participated in regulatory meetings and drove execution of follow up actions and new studies.• Worked with CMC leads to move multiple cell therapy components to GMP manufacturing partners.• Worked with CSO and CMO to develop Casebia’s autoimmune disease strategy. -
Director Project Management, Liver, Hsc And Autoimmune DiseaseCasebia Therapeutics May 2017 - Oct 2018Cambridge, Ma, Us• Lead discovery research teams to develop preliminary project timelines across diverse indications.• Developed early target product profiles to help guide discovery research teams.• Worked with cross functional teams at both Casebia and Crispr Therapeutics. • Established a strategic collaboration work plan with Seattle Children’s Research Institute.• Worked with project team to enable key liver lipid nanoparticle based editing technologies
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In Vitro Pharmacology Group LeaderBayer Healthcare Dec 2013 - Apr 2017Leverkusen, North Rhine-Westphalia, DeHematology early research in vitro pharmacology group leader•Contribute to the development of the hematology early research portfolio strategy•Lead a 9 member team of staff scientist, technical scientists and postdocs•Lead early research projects from target identification through lead candidate selection•Our group supports all early research projects in the hematology portfolio •Scientists within the group lead projects as well as develop novel methods•Responsible for forecasting and monitoring the departmental budget including external collaborations -
In Vitro Mechanism Of Action Group LeaderBayer Healthcare Apr 2011 - Dec 2013Leverkusen, North Rhine-Westphalia, De•Leader of a highly skilled in vitro research team, our responsibilities include:•Identify and develop new biotherapeutics in support of the hematology portfolio•Demonstrate the mechanism of action of novel biotherapeutics•Develop in vitro assays to support drug development•Lead optimization project leadership•Supervise international collaborations with CROs and academic groups
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Staff ScientistBayer Healthcare Oct 2006 - Apr 2011Leverkusen, North Rhine-Westphalia, De•Responsible for modeling and engineering new protein based therapeutics.•Developed kinetic assays for extended characterization of protein therapeutics.•Determined mechanism of action for novel in-licensed therapies.•Provided technical due diligence for the acquisition of the Maxygen hematology portfolio.•Developed SPR based binding assay for new Kogenate® liposome formulation currently in clinical trials.•Regularly presented data at site wide seminars, group meetings and as part of a project team.•Co-inventor on three filed patent applications.
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Development ScientistApplied Biosystems Mar 2006 - Oct 2006Waltham, Ma, UsDeveloped assays for new reagents and future products; polymerase enzymology and assay development. -
Research Assistant, Pharmaceutical Sciences,The University Of Kentucky, College Of Pharmacy Aug 1999 - Aug 2000• Worked with Dr. Marcos Oliveira to set up a new lab, write grants, and start several projects and collaborations in biochemistry and drug design.• Conducted research on purification of an antibiotic target, Arginine Decarboxylase, for kinetic investigation and crystallization trials.
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Research Assistant, Developmental BiologyUniversity Of Texas 1998 - 1999Austin, Tx, Us• Performed molecular biology research in Dr. Karen Artzt’s laboratory in conjunction with post doctoral fellows and graduate students.• Researched new RNA binding proteins from mouse chromosome 17; searched for new Quaking gene family members using affinity columns and phage libraries.• Isolated the key functional RNA binding domain of the Quaking family for high level expression, purification, and crystallization.
Chandra Patel Skills
Chandra Patel Education Details
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University Of KentuckyPharmaceutical Sciences -
The University Of Texas At AustinMolecular Biology
Frequently Asked Questions about Chandra Patel
What company does Chandra Patel work for?
Chandra Patel works for Gentibio
What is Chandra Patel's role at the current company?
Chandra Patel's current role is Co-Founder, Senior Vice President R and D Operations.
What is Chandra Patel's email address?
Chandra Patel's email address is pa****@****ail.com
What schools did Chandra Patel attend?
Chandra Patel attended University Of Kentucky, The University Of Texas At Austin.
What skills is Chandra Patel known for?
Chandra Patel has skills like Assay Development, Pharmaceutical Industry, Protein Chemistry, Biochemistry, Biotechnology, Drug Development, Protein Engineering, Protein Expression, Molecular Biology, Drug Discovery, Clinical Trials, Project Management.
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