Charles Hellec Email & Phone Number

Paris, Fr

Villejuif, Île-De-France, France

𝗖𝗼𝗻𝘁𝗲𝘅𝘁• The ARC foundation organizes fundraising actions to support cancer research • The ARC foundation also aims to interest and inform a widespread audience about cancer biology𝗠𝗮𝗶𝗻 𝘁𝗮𝘀𝗸𝘀• Simplify complex scientific content in order to reach a larger audience by writing pedagogical texts and making schemes from research articles• Transfer scientific information to other collaborators in preparation for the different actions of the ARC foundation• Involvement in editorial choices of online and printed publications𝗧𝗲𝗮𝗺𝘄𝗼𝗿𝗸 𝗮𝗻𝗱 𝗰𝗼𝗺𝗺𝘂𝗻𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝘀𝗸𝗶𝗹𝗹𝘀• Daily collaboration with the marketing and communication teams- Writing of simple texts to reach a large non-scientific audience and grab their interest in cancer research• Daily collaboration with sponsor-relationship teams - Tailor-made communication: the content depends on who it is made for, in terms of literary style and scientific complexity

Nagoya, Aichi, Japan

𝗖𝗼𝗻𝘁𝗲𝘅𝘁• Graduate School of Pharmaceutical Sciences, Nagoya City University• Department of Structural Biology and Biomolecular Engineering• JSPS Postdoctoral Fellowship• Research project : "Link between protein-specific glycosylation mechanisms and organelle zones in the case of the sialyltransferase-induced modification system"𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗳𝗼𝗰𝘂𝘀𝗲𝘀• Labelling of endogenous enzymes • Analysis of subcellular localization𝗟𝗮𝗯𝗼𝗿𝗮𝘁𝗼𝗿𝘆 𝘀𝗸𝗶𝗹𝗹𝘀• Cell biology : mammalian cell HCT116 culture, establishement of modified HCT116 cell lines, bacteria culture, luorescence miccroscopy• Molecular biology and genetic engineering : chimeric protein design, CRISPR/Cas9 technique for gene knock-in, HaloTag technique for gene knock-in, endogenous labelling𝗧𝗲𝗮𝗰𝗵𝗶𝗻𝗴 𝗲𝘅𝗽𝗲𝗿𝗶𝗲𝗻𝗰𝗲• Biology introduction conference at Okazaki Senior High School, Okazaki, Aichi prefecture, Japan

Unité De Glycobiologie Structurale Et Fonctionnelle (Ugsf) - Umr 8576 Cnrs

𝗖𝗼𝗻𝘁𝗲𝘅𝘁• Research team : "Heparan sulfate diversity and inflammatory response regulation", team leader : Pr. Fabrice Allain• Research project : "Heparan sulfate 3-O-sulfotransferases (HS3STs) involvement in cellular processes linked to cancer", under the supervision of Pr. Fabrice Allain𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗳𝗼𝗰𝘂𝘀𝗲𝘀• Study of the HS3ST-overexpressing breast cancer cell behaviour• Analysis of the HS3ST-overexpressing breast cancer cell signalling• Deciphering of the underlying molecular mechanism involved in HS3ST-overexpressing breast cancer cells𝗟𝗮𝗯𝗼𝗿𝗮𝘁𝗼𝗿𝘆 𝘀𝗸𝗶𝗹𝗹𝘀• Cell biology : culture of mammalian cells and bacteria, isolation and culture of primary human blood cells, viability test, proliferation assay, colony formation assay, cytotoxicity experiments, cell migration/invasion assay, immunofluorescence experiments• Biochemistry : SDS-PAGE and western-blot, glycosaminoglycans extraction, RP-HPLC, MS analysis of glycosaminoglycans• Molecular biology and genetic engineering : RNA/DNA extraction and purification, retrotranscription, PCR, real-time PCR, cloning, vector design, site-directed mutagenesis, gene silencing (siRNA), transient and stable overexpression𝗧𝗲𝗮𝗰𝗵𝗶𝗻𝗴 𝗲𝘅𝗽𝗲𝗿𝗶𝗲𝗻𝗰𝗲• Teaching assistant (64 hours per year), tutorial and practical courses in biochemistry for second and third year undergraduate students

Doctor Of Philosophy - Phd, Cellular And Molecular Aspects Of Biology, Speciality Biochemistry And Molecular Biology

Master Of Science - Ms, Biochemistry And Molecular Biology, High Honors

Bachelor Of Science - Bs, Biochemistry, High Honors

Medical School Studies, Medicine

High School, Obtention Of The French Scientific Baccalauréat