• Commercializing neuromodulation technology that enhances sensory acuity while worn• Reduces misperceptions by enhancing the brain's ability to clearly process vision, hearing, and touch• Selected for Columbia's Biomedical Tech Accelerator (BiomedX), NYC's HealthTech Entrepreneurship Lab (ELabNYC), The Columbia Startup Lab, Columbia Venture Competition (2nd Place Tech Challenge 2021, 1st Place Startup Challenge 2022), The Comcast NBCUniversal SportsTech Accelerator, The Cornell Tech Postdoc Startup Runway Program, Long Island's High Tech Incubator (LIHTI), the National Science Foundation's Innovation Corps (NSF I-Corps), Creative Destruction Lab, and The Wall Street Journal's 2024 Future of Everything Festival• Investors including Joyance Partners, Social Starts Health and Happiness Fund, Plug and Play Tech Center, Chokshi Family LLC, Yuchia Lin, 5150 Capital, Cornell Tech, and ComcastNBC SportsTechwww.SharperSense.comRelated press:• https://podcasts.apple.com/us/podcast/guest-charles-rodenkirch-ceo-of-sharper-sense/id1458134604?i=1000536784771• https://blog.lifesciencemarketresearch.com/medtech-startups-neuro42-onerahealth-sharper-sense-more• https://joyance-partners.medium.com/where-we-are-investing-now-next-gen-neurotech-93724c30cbf• https://www.bci-award.com/2023• https://datarootlabs.com/blog/the-state-of-neurotech-unlocking-minds-and-new-markets• https://podcasts.apple.com/us/podcast/neurostimulation-the-future-of-sensory-enhancement/id1688014210?i=1000637531789• https://primelifepodcast.com/2024/03/28/73-using-new-technology-to-detect-and-treat-hearing-loss-with-charles-rodenkirch/• https://www.dowjones.com/press-room/the-wall-street-journal-announces-lineup-for-future-of-everything-festival-lab-preview-night/• https://www.nature.com/articles/s41598-024-54026-8• https://www.f6s.com/companies/neuroscience/united-states/new-york/no

• Visit our website at www.neuro-nyc.com• Collaboration between neurotech companies in NYC including OpenBCI, Synchron, and Sharper Sense• Hosts industry events that further collaboration within the burgeoning NYC neurotech scene

• Continued research into neuromodulation technologies for enhancing central sensory processing in humansRelated Press:• https://tech.cornell.edu/news/cornell-tech-startup-sharper-sense-works-to-improve-sensory-performance-in-humans/

• A selective program that is part business school, part research institution, and part startup incubator• Supports Sharper Sense by providing two years of facilities, funding, and business mentorship• https://tech.cornell.edu/news/cornell-tech-startup-sharper-sense-works-to-improve-sensory-performance-in-humans/Related press:• https://www.tech.cornell.edu/people/charles-rodenkirch/• https://www.ynet.co.il/health/article/hjfsflho2

• A highly selective program that helps startups build successful and sustainable business relationships• Worked with top names in sports including NASCAR, US Golf, Us Ski & Snowboard, and USA Cycling• A launchpad for exploring sports and esports applications of Sharper Sense’s sensory enhancing techRelated Press:• https://venturebeat.com/2021/02/22/comcast-nbcuniversal-picks-10-sports-and-esports-startups-for-sportstech-accelerator/• Sharper Sense ComcastNBC SportsTech Intro Video: https://youtu.be/GIxq4aCuAVE• https://www.comcastsportstech.com/inside-track/form-and-function-how-wearables-are-changing-sports/• Sharper Sense ComcastNBC SportsTech Demo Day Video: https://www.youtube.com/watch?v=X7V08cXmm7c• https://frontofficesports.com/comcast-invests-in-future-of-sports-tech/• https://www.comcastsportstech.com/inside-track/startup-showcase-how-sharper-senses-wearable-neurotechnology-enhances-athlete-performance/• https://www.sportsbusinessjournal.com/Daily/Issues/2021/09/22/Technology/startups-roundtable-project-admission-sharper-sense-byga.aspx• https://www.comcastsportstech.com/inside-track/keeping-up-with-the-alums/

• Developing closed-loop brain-machine interfaces for optimizing perceptual state in an intelligent mannerRelated Press:• https://www.engineering.columbia.edu/news/engineers-take-home-top-prizes-in-startup-competition• https://www.engineering.columbia.edu/news/columbia-technology-ventures-pitch-day-entrepreneurs• https://entrepreneurship.columbia.edu/2022/05/12/2022-columbia-venture-competition-winners-startupcolumbia-challenge/• https://www.mdpi.com/2079-7737/13/2/79

• Investigated how attention/arousal affects transmission/processing of sensory information in the brain• Used the latest brain-machine interfaces, biological tools, computational modeling, and statistical analysis• Led our lab’s involvement in DARPA’s Targeted Neuroplasticity Training (TNT) program• First-author publication in Nature Neuroscience on norepinephrine modulation of sensory processing• Translated research into multiple patents for neuromodulation systems that enhance sensory acuityRelated press:• https://www.bme.columbia.edu/april-2021-bme-blaze-charles-rodenkirch• https://www.eurekalert.org/news-releases/670993• https://link.springer.com/chapter/10.1007/978-3-319-31433-4_8• https://www.nature.com/articles/s41593-018-0283-1• https://iopscience.iop.org/article/10.1088/1741-2552/ab6b84/meta• https://www.cell.com/cell-reports/fulltext/S2211-1247(17)31236-6• https://www.nature.com/articles/ncomms13289• https://patents.google.com/patent/US20230218889A1/en• https://patents.google.com/patent/US20220096834A1/en

• Selective six-month training and mentorship program for aspiring entrepreneurs in health technology• Launched by the Bloomberg Administration and NYC Economic Development Corporation• Mini-MBA curriculum covers market analysis, business plan development, intellectual property, clinical data preparation, valuation & venture financing, investor communications, regulatory affairs, marketing & sales, financial management, and strategic partnershipsRelated press:• https://www.elabnyc.com/directory/charles-rodenkirch/

• Technology transfer and intellectual property management for Columbia University• Assessed early-stage academic technology and helped transfer it to the market via licensing deals

• ALS-associated mutations that cause protein misfolding/aggregation linked with neurodegeneration

• Age-related macular degeneration and degraded self-repaid of cell membranes via lysosome fusion• Time-lapse imaging and analysis of lysosome-membrane fusion in transfected cell cultures• Funded by the UW-Madison's Hilldale Undergraduate Fellowship and Fight for Sight's Student FellowshipRelated Press:• https://awards.advising.wisc.edu/campus-wide-award-recipients/test-hilldale-fellows/

• Nonprofit corporation leasing tournament quality boats to collegiate waterski and wakeboard teams• Helped original board of directors form the corporation in 2012 and took over as president in 2013• Secured and repaid a $23K business loan that allowed us to upgrade an aging fleet • Corporation has had continued success and is still actively leasing to the University of Wisconsin-Madison

• Cell phone repair targeted at the rapidly growing smartphone market• Offered both walk-in and mail-in service via a physical storefront and website• Won UW-Madison’s 2012 Student Business Incubator competitionRelated press:• https://www.ibmadison.com/in-business-madison/ac-cell-erating-repairs/article_ab6181fa-8289-510d-90bb-3011b7dadc4f.html• https://royalpurplenews.com/8318/uncategorized/students-phone-repair-business-offers-24-hour-deadline/

• Hardware repair and data recovery for UW-Madison’s computer systems