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Executive and entrepreneur in genomics with 20 years of experience, with the goal of making clinical genomics easier, more useful, and more widely used. I specialize in the development of computational methods, but am driven by deeply understanding the molecular biology that drives all discovery. Most of my experience is in cancer, but I am interested all applications of genomics in biology.In the past decade I have worked on CLIA whole-genome and whole-transcriptome sequencing from FFPE and blood, fragmentomics of blood plasma and urine cell-free DNA. My computational efforts include probabilistic graphical models for integration of multi-omic cancer data with pathway signaling, and I have lead a research team using deep-learning on sequence analysis as well as and cancer histopathology images.
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Vp Of BioinformaticsClear Labs Mar 2022 - PresentSan Carlos, California, Us -
Vp BioinformaticsClaret Bioscience Dec 2019 - Mar 2022Santa Cruz, Ca, UsI lead the development of a cfDNA fragmentomics research program, and the bioinformatic analysis of rootless hair for forensic genealogy. Claret has two unique sequencing techniques, one which reveals the overhang content from double-stranded DNA, and the other which recovers the native 3' ends of single-stranded and double-stranded DNA.I hired and trained a team to advance the fragmentomics research program and work hand-in-hand with the wet lab research & development team to deliver new products and improve current products. -
Executive Vice President, Genomic ResearchNantomics, Llc Aug 2014 - Dec 2019NantOmics resulted from the acquisition of Five3 Genomics. At NantOmics I executed the CLIA approval of whole genome sequencing of tumor normal pairs, as well as whole transcriptome RNA-seq from FFPE tumor samples. I lead a research team that integrated deep-learning on both DNA sequence models and histopathology image analysis.
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Chief Scientific OfficerFive3 Genomics, Llc Apr 2011 - Aug 2014Directing cancer research program, design of computational infrastructure to handle efficient processing and analysis of whole genome sequencing and whole transcriptome sequencing.
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Postdoctoral FellowUniversity Of California, Santa Cruz Jul 2010 - Mar 2011Santa Cruz, Ca, UsIntegration of multiple cancer genomics data types with pathway information -
Postdoctoral Research AssociatePrinceton University Sep 2009 - Jul 2010Princeton, Nj, Us -
Graduate StudentUniversity Of California, Santa Cruz 2003 - Nov 2009Santa Cruz, Ca, Us
Charles Vaske Skills
Charles Vaske Education Details
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University Of California, Santa CruzBioinformatics -
Washington University In St. LouisMath
Frequently Asked Questions about Charles Vaske
What company does Charles Vaske work for?
Charles Vaske works for Clear Labs
What is Charles Vaske's role at the current company?
Charles Vaske's current role is Bioinformatics at Clear Labs.
What is Charles Vaske's email address?
Charles Vaske's email address is cv****@****ail.com
What is Charles Vaske's direct phone number?
Charles Vaske's direct phone number is +183133*****
What schools did Charles Vaske attend?
Charles Vaske attended University Of California, Santa Cruz, Washington University In St. Louis.
What are some of Charles Vaske's interests?
Charles Vaske has interest in Christianity, Kids, Cooking, Electronics, Traveling, Sewing, Outdoors, Home Improvement, International Traavel, Reading.
What skills is Charles Vaske known for?
Charles Vaske has skills like Computational Biology, Bioinformatics, Genomics, Molecular Biology, Genetics, Sequence Analysis, R, Life Sciences, Machine Learning, Sequencing, Research, Biochemistry.
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