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Proven research team leader with experience managing complex discovery programs and partnerships. 15 years of experience in cancer biology including epigenetics, chromatin remodeling and cell cycle biology. 8 years of industry experience in drug discovery focused on delivering small molecules for oncology and immuno-oncology applications. Project leader with cross-functional co-located and virtual teams, in addition to managing academic collaborations. Experienced managing teams through all aspects of the drug discovery process including: (i) Development of high-throughput biochemical and cellular assays to inform SAR, (ii) Discovery and validation of new biomarkers, (iii) Elaboration of therapeutic hypothesis to inform translational plans and patient stratification strategy. Demonstrated ability to deliver on project milestones and to engage internal and external stakeholders.Beyond drug discovery, well established technology development track record. International background and work experience with fluency in English, French and Italian.
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Senior DirectorBlueprint Medicines Jul 2022 - PresentCambridge, Massachusetts, UsBiology and Targeted Protein Degradation -
DirectorBlueprint Medicines Jan 2021 - Jul 2022Cambridge, Massachusetts, Us -
Associate DirectorBlueprint Medicines Jul 2018 - Dec 2020Cambridge, Massachusetts, Us -
Principal ScientistForma Therapeutics, Inc. Mar 2017 - Jun 2018Watertown, Massachusetts, Us -
Senior ScientistForma Therapeutics, Inc. Nov 2011 - Mar 2017Watertown, Massachusetts, UsBuilt program to deliver small molecules against a family of targets with potential applications in oncology and immune-oncology. Project leader managing a team composed of co-located members as well as academic collaborators and CROs. Developed biochemical and cellular assays to support in vitro pharmacology and to drive SAR in order to inform the selection of the lead compounds and in vivo models for PK/PD/efficacy studies. Elaborated mechanistic and therapeutic hypothesis, identified biomarkers and developed translational plans. Experienced and effective at driving programs to go/no-go decision points to help prioritize targets within the portfolio. -
Research ScientistBelfer Institute For Applied Cancer Science, Dana-Farber Cancer Institute Mar 2009 - Nov 2011Boston, Ma, UsLead project from hit-to-lead to lead optimization. Successfully defined pathway map and cross-talks with other pathways. Identified and validated relevant biomarkers. Established testing funnel to characterize small molecules and nominate the lead tool compound for in vivo studies. Established in vivo dosing paradigm to achieve appropriate PK/PD. Responsible for genetically validating new target and reaching go/no-go decision. -
Post-Doctoral FellowNational Cancer Institute Oct 2005 - Feb 2009Bethesda, Md, UsIn this position I transferred the Molecular Combing technology into the National Cancer Institute from the Pasteur Institute. The focus of my research was primarily on the cell cycle regulation, checkpoint, DNA replication and chromatin. I applied Molecular Combing to the study of CHK1, Bloom and the Histone Deacetylase (HDAC) inhibitor SAHA (vorinostat). In this position I published seven peer-reviewed articles in multiple journals including Cancer Research and Nature Cell Biology. -
Post-Doctoral FellowPasteur Institute, France Mar 2001 - Jun 2005Lead laboratory scientist developing innovative new DNA manipulation and imaging approach called Molecular Combing. Research resulted in both publications as well as commercialized technologies.
Chiara Conti Skills
Chiara Conti Education Details
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Università Degli Studi Di FerraraGenetics -
Pierre And Marie Curie UniversityHuman Genetics -
Università Degli Studi Di PadovaMolecular Biology
Frequently Asked Questions about Chiara Conti
What company does Chiara Conti work for?
Chiara Conti works for Blueprint Medicines
What is Chiara Conti's role at the current company?
Chiara Conti's current role is Senior Director at Blueprint Medicines.
What is Chiara Conti's email address?
Chiara Conti's email address is co****@****ail.com
What is Chiara Conti's direct phone number?
Chiara Conti's direct phone number is +161767*****
What schools did Chiara Conti attend?
Chiara Conti attended Università Degli Studi Di Ferrara, Pierre And Marie Curie University, Università Degli Studi Di Padova.
What are some of Chiara Conti's interests?
Chiara Conti has interest in Fluent In French, English And Italian, Languages.
What skills is Chiara Conti known for?
Chiara Conti has skills like Drug Discovery, Cell Biology, Cancer, Cancer Research, Oncology, Molecular Biology, Dna, Biochemistry, Pharmaceutical Industry, Life Sciences, Lifesciences, Assay Development.
Who are Chiara Conti's colleagues?
Chiara Conti's colleagues are Igor Gridnev, Michaela C. Haeger, Tanya Green, Xinyue (Maggie) Ma, Linh Ho, Torsten Herbertz, Kankana Bardhan, Ph.d..
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