Chiara Orciani Email & Phone Number

Laval, Quebec, Canada

• Single control point of nonclinical GLP toxicology and safety pharmacology studies. MRI-targeting scientist in dogs and non-human primates for neuroscience studies.Responsibilities:
• Design and write study plans after extensive discussions with Sponsors.
• Conduct in-life monitoring.
• Coordinate the multisite study activities (Canada – US), the study’s logistics with the Sponsor, and communicate the milestones to the departments.
• Conduct the analysis and interpretation of the results.
• Write reports and publications for Sponsors, including manuscripts, posters, abstracts, and literature analyses.

Laval, Quebec, Canada

Montreal, Canada

• Lead in vivo studies in Alzheimer’s disease and aging following the cholinergic hypothesis.Responsibilities:
• Design the studies, conduct the main experiments, interpret the results, and write the manuscripts for the following projects:(1) The effect of basal forebrain cholinergic neurons' deprivation on neurotrophins and.
• Write grant applications (NIH, CIHR), perform statistical analysis, and help to train new students.
• Collaborator of studies about neuroinflammation and oxidative stress in individuals and animal models.

Milano, Italia

• Technical support and experiment execution for a project aiming to use cholesterol-loaded nanoparticles as a therapeutic avenue to reduce Huntington's disease hallmarks in a mouse model.Responsibilities:
• Animal genotyping
• Perform behavioral tests for memory (NOL/R) in rodents
• Perform biochemical (western blots) and molecular biology (qPCR) analyses of the samples
• Prepare stock solutions for laboratory use.