Ching Ann Tee Email & Phone Number

Singapore

Singapore

• Identify Critical Quality Attributes (CQAs) for efficacy of stem cell therapies in tissue regeneration and immunomodulation.• Identify Critical Process Parameters (CPPs) for production of stem cells with desired characteristics and quality. • Improved cell yield by >300 folds, reduced cellular senescence and lowered cellular heterogeneity by incorporating identified CPP and CQA in stem cell manufacturing processes.• Patented a technology to evaluate the CQA of stem cells in a… Show more • Identify Critical Quality Attributes (CQAs) for efficacy of stem cell therapies in tissue regeneration and immunomodulation.• Identify Critical Process Parameters (CPPs) for production of stem cells with desired characteristics and quality. • Improved cell yield by >300 folds, reduced cellular senescence and lowered cellular heterogeneity by incorporating identified CPP and CQA in stem cell manufacturing processes.• Patented a technology to evaluate the CQA of stem cells in a label-free and non-destructive manner. • Work with professionals from different background to develop in-process monitoring and control technologies that can be translated into a GMP production environment.• Co-ordinate projects across geographical borders via project management software and teleconferences.• Engage in industrial collaboration to drive shared objectives in improving cell yield and quality. Show less

Singapore

• Worked closely with clinicians to evaluate the efficacy of a newly developed cell manufacturing platform on clinical samples.• Produced experimental data to enable translation of project into clinical trial.

Singapore

• Developed a therapeutic cell production protocol by integrating dynamic microcarrier culture and inertial spiral microchannel device which progress into a pre-clinical study involving porcine osteochondral defect model. • Contributed to securing a research grant of more than a million dollar with novel data generation.• Planned and executed projects with various professionals (clinician, scientist, veterinarian, laboratory technician).• Managed and communicated projects across the… Show more • Developed a therapeutic cell production protocol by integrating dynamic microcarrier culture and inertial spiral microchannel device which progress into a pre-clinical study involving porcine osteochondral defect model. • Contributed to securing a research grant of more than a million dollar with novel data generation.• Planned and executed projects with various professionals (clinician, scientist, veterinarian, laboratory technician).• Managed and communicated projects across the geographical borders through written email and teleconferences.• Demonstrated good writing and communication skill as evidenced by six peer-reviewed publications and three international conference presentations. Show less

Cam

• Quick to learn advanced techniques in the field of spiral microfluidics and transferred the technology to Singapore. • Acquired new skills in a short time frame for innovative application in mesenchymal stem cell characterization.

Singapore

An undergraduate researcher in the Undergraduate Research Experience on Campus (URECA) program. Scope• Co-authored article on intervertebral disc engineering.• Provided technical supports and advice in experimental issues for the research group members.• Gained technical experience in the field of multi-disciplinary tissue engineering research. • Assisted in the design of a 3D microfluidic device for the engineering of tissues with a multilayer… Show more An undergraduate researcher in the Undergraduate Research Experience on Campus (URECA) program. Scope• Co-authored article on intervertebral disc engineering.• Provided technical supports and advice in experimental issues for the research group members.• Gained technical experience in the field of multi-disciplinary tissue engineering research. • Assisted in the design of a 3D microfluidic device for the engineering of tissues with a multilayer interface.• Investigated the relationship between scaffold orientation and cell morphology in MSC differentiation.• Generated in vitro annulus intervertebral disc constructs using interfacial polyelectrolyte complexation scaffold. Show less

Singapore

Student under Youth Research Program (YRP) at Institute of Bioengineering and Technology (IBN).Scope• Planned and executed a study on the mechanobiology of mesenchymal stem cells. • Improved the hydrogel (controllable mechanical properties) synthesis protocol with high reproducibility.• Studied cell proliferation and adhesion efficiency on different hydrogel stiffness through PICO green assay and identification of cell phenotype through qRT-PCR.

Doctor Of Philosophy - Phd, Biomedical/Medical Engineering

Bachelor Of Engineering (Honours), Bioengineering And Biomedical Engineering