Chris Clee Email & Phone Number

St Neots, Cambridgeshire, United Kingdom

Day to day management of a medium sized school network, with additional data management responsibility.

Oxford

I am currently helping the project management group at WTCHG, on a part time basis. The role involves customer advice, quote generation, and following samples through the pipielines to project conclusion.

I was a member of the central sequencing services at the WTSI for over twelve years. I headed up the wet lab section running a number of groups utilising various platforms, and formed part of the senior sequencing management group. During my tenure I....• Created the original centralised sanger sequencing pipeline, including working with Jim Mulikin, and John Attwood to facilitate data monitoring for maximal accountability and transparency.• Whilst managing the facility I tested… Show more I was a member of the central sequencing services at the WTSI for over twelve years. I headed up the wet lab section running a number of groups utilising various platforms, and formed part of the senior sequencing management group. During my tenure I....• Created the original centralised sanger sequencing pipeline, including working with Jim Mulikin, and John Attwood to facilitate data monitoring for maximal accountability and transparency.• Whilst managing the facility I tested and implemented each generation of capillary based technology as they arrived, adapting the monitoring systems as necessary. • Helped to implement two “Next Generation Technology” systems into the current DNA sequencing process (Illumina and 454) and worked to investigate a third (SOLiD). This included liaising with groups within Sanger and competing supply companies. • Presented data from these systems, including keynote lectures, both at external conferences and internally. • Set up two high throughput laboratories, which have delivered all of their tasks on time and within budget.• Economised through the implementation of shift-working, development of new working practices across the sequencing production group, limiting waste due to human error and by developing new techniques to operate instrumentation.• Set up a ‘Black Box’ facility for data capture, where data were collected, and returned automatically to the customer. • Created a loyal, highly integrated and motivated group, most of whom are still working at the Institute.• Implemented Cross-training across the production teams, thus maximising support to all sections within the group as a whole. • Created and maintained links across industry and other academic institutes, which has helped to maintain the Institute’s ‘cutting edge’ position on the world platform.• In excess of 20 publications including a book chapter on the Sanger production process. Numerous public scientific presentations. Show less

In charge of wet lab duties for the Radiation hybrid mapping programme undertaken as part of the Human Genome Project.• Developed and implemented a high throughput mapping system for use in the human genome sequencing programme under Panos Deloukas and David Bentley. • Worked closely with the engineering group to produce a unique automation platform as well as a bespoke image capturing system for high throughput analysis of mapping data.• Involved in the interviewing and… Show more In charge of wet lab duties for the Radiation hybrid mapping programme undertaken as part of the Human Genome Project.• Developed and implemented a high throughput mapping system for use in the human genome sequencing programme under Panos Deloukas and David Bentley. • Worked closely with the engineering group to produce a unique automation platform as well as a bespoke image capturing system for high throughput analysis of mapping data.• Involved in the interviewing and selection of sandwich students. • Publications 4. Public scientific presentations 2. Show less

Cambridge Science Park

• Evaluated various EST markers for their use in wheat and barley breeding programmes.• Developed non-radioactive detection systems for both restriction fragment length polymorphism analysis (RFLP) and slab gel based sequencing techniques.• Trained to RPS level for handling P32.• Developed PCR based tests for genes highlighted by the above techniques• Successful in converting an EST based RFLP, to PCR for Barley Yellow Mosaic virus (also thought to cause Rhizomania in sugar… Show more • Evaluated various EST markers for their use in wheat and barley breeding programmes.• Developed non-radioactive detection systems for both restriction fragment length polymorphism analysis (RFLP) and slab gel based sequencing techniques.• Trained to RPS level for handling P32.• Developed PCR based tests for genes highlighted by the above techniques• Successful in converting an EST based RFLP, to PCR for Barley Yellow Mosaic virus (also thought to cause Rhizomania in sugar beet).• Gained many basic molecular biology techniques. Gave first public poster presentation to the AAB in June 1991.• Publications 3 Show less