Chris Patte Email & Phone Number

Apex, Nc, Us

Apex, Nc

Bradenton, Fl

Biological Scientist, Department of Plan PathologyGulf Coast Research and Education Center, Bradenton, FLGeminiviruses, a family of single stranded DNA plant viruses transmitted by whiteflies, cause economic damage to agricultural crops in Florida. I identified and molecularly characterized several new geminiviruses; participated in the development of successful management practices for these viruses; and played an important role in the development of transgenic plants that use gene silencing to produce immunity to those viruses. Identify and molecularly characterized new geminiviruses Participated in the development of successful management practices of geminiviruses Played an important role in the development of transgenic plants that use gene silencing to produce immunity to geminiviruses Design, develop, and perform new protocols for use in molecular biology, plant virology, and biochemistry research.  Evaluate and apply new bioinformatics software as appropriate. Design, develop, and test new products for commercial use.  Build on previous and current experimental results to develop new projects and new avenues of research.  Maintain research projects while staying within the confines of a budget.  Supervise graduate students (3), undergraduates (2), and lab technicians (6). Teach and guide post-doctorates and graduate students in techniques and theories to further their independent projects.  Write refereed publications, annual reports, and present results at scientific meetings.

Durham, Nc

Biological Research Analyst, Department of SurgeryDivision of Experimental Surgery and Transplant ImmunologyIn xenotransplantation, the recipient’s first contact with the donor organ is the endothelium of the vessel wall. Natural antibodies within the recipient’s serum bind to the endothelial cell, which leads to induce complement activation and destruction of the integrity of the endothelium. The response is detrimental to the barrier capability of the vessel wall, leading to the rejection of the transplanted organ. I examined the cardiac endothelial response, including the complex signaling pathways in the endothelial cell affected by natural antibody and complement.  Examined the cardiac endothelial response, including the complex signaling pathways in the endothelial cell affected by natural antibody and complement Designed, developed, and performed new protocols for use in molecular biology, immunology, and biochemistry research.  Supervised undergraduates (2), and lab assistants (2).  Built on previous and current research to develop new projects and new avenues to explore. Trained and guided Research Fellows (4) and undergraduates (5) in techniques and theories to further their independent projects.