Christopher Callas Email and Phone Number
Masters-level organic and medicinal chemist with experience in total synthesis and drug discovery. Interested in reaction discovery, synthesis of bioactive molecules, and the application of organic chemistry to biological problems. Spent 3 years in the Wengryniuk Lab at Temple University as an undergraduate researcher working on natural product total synthesis, followed by 2 years at the Janssen Pharmaceutical Companies of Johnson & Johnson as a medicinal chemist working in oncology drug discovery. Obtained a Masters degree working in the Levin Lab at the University of Chicago on radical deaminative functionalization chemistry.
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Associate Scientist Ii, Global Discovery ChemistryJohnson & Johnson Innovative MedicineJenkintown, Pa, Us -
Associate Scientist Ii, Global Discovery ChemistryJohnson & Johnson Innovative Medicine Aug 2024 - PresentSpring House, Pennsylvania, United States• Generates innovative design ideas leveraging state of the art medicinal chemistry techniques/tools such as: SPARK analysis, scaffold hopping, ligand-based drug design (LBDD), structure-based drug design (SBDD), ML/AI property prediction, MOE, PyMOL• Applies AI/ML predictions and existing SAR knowledge to identify most promising designs• Independently plans and executes syntheses towards highest priority compounds• Spearheads global adoption of automation efforts for assay submission aimed at decreasing DMTA cycle times• Leads ADME and NCS assay submission• Prioritizes Diversity, Equity, and Inclusion (DEI) by conducting outreach activities for both high school and undergraduate students -
Associate Scientist, Global Discovery ChemistryJohnson & Johnson Innovative Medicine Oct 2023 - Aug 2024Spring House, Pennsylvania, United States• Independently synthesized, purified, and characterized novel drug compounds on 2 immunology projects• Collaborated with project colleagues to design novel analogues and prioritize them for synthesis• Worked closely with computational colleagues to refine design hypotheses and AI models for property prediction• Led ADME and NCS assay submission efforts to drive decision-making and compound progression• Interfaced with CRO colleagues to ensure efficient route design and execution and to maintain high-quality analytical data• Managed an undergraduate summer intern on a novel research project -
Graduate Student ResearcherUniversity Of Chicago Sep 2022 - Jun 2023Chicago, Illinois, United StatesStudied novel radical deaminative functionalization strategies in the Levin Group. -
Assistant Scientist, Discovery ChemistryThe Janssen Pharmaceutical Companies Of Johnson & Johnson Jun 2020 - Jul 2022Spring House, Pennsylvania, United States• Independently synthesized, purified, and characterized novel drug compounds on 2 oncology drug discovery campaigns • Learned medicinal chemistry principles and applied them towards rational design of new compounds• Developed and adapted synthetic routes towards desired building blocks and analogues• Collaborated with computational colleagues to inform structure-based drug design • Proficient with techniques such as NMR, LC-MS, normal/reverse phase chromatography (automated), air-free reaction set-up -
Spanish/English Conversation PartnerTemple Jan 2020 - May 2020Philadelphia, Pennsylvania, United States• Conducted 1-on-1 language tutoring sessions for both Spanish and English language learners. -
Undergraduate Research AssistantTemple University Sep 2017 - May 2020Advisor: Dr. Sarah E. Wengryniuk• Carried out research towards the total synthesis of the Heliannuol family of herbicidal natural products. -
Peer-Assisted Study Session (Pass) LeaderTemple University Aug 2019 - Dec 2019Philadelphia, Pennsylvania• Led group study sessions for students of all years (Freshman - Senior) in Elementary Classical Physics 1. -
Discovery Chemistry InternMerck Jun 2019 - Aug 2019West Point, Pa• Worked alongside Medicinal Chemists to advance a small molecule pharmaceutical program• Contributed ideas and insights pertaining to the active synthetic routes• Worked independently and efficiently in an industry lab setting• Greatly broadened knowledge of synthetic organic chemistry • Gained ample experience with various purification techniques and instruments, such as automated reverse phase and normal phase chromatography• Expanded knowledge of structural elucidation through techniques such as NMR spectroscopy and LC-MS -
Bioarchaeology InternThe American School Of Classical Studies At Athens Jun 2017 - Jul 2017Athens, Greece• Worked in the Malcolm H. Wiener Lab for Archaeological Science• Received training in Bioarchaeology• Assisted in the study of human remains from a prehistoric (Mycenaean) cemetery in Greece• Cleaned and sorted primary burials and commingled human remains• Aided in skeletonization of birds to be added to the comparative collection of the lab -
Content AssociateCasenetwork Mar 2014 - Mar 2016Philadelphia, Pa• Uploaded and edited simulated OB/GYN and Family Practice case content to online training interface for Residents and Medical Students
Christopher Callas Education Details
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Chemistry -
Spanish Language And Literature -
Jenkintown High School
Frequently Asked Questions about Christopher Callas
What company does Christopher Callas work for?
Christopher Callas works for Johnson & Johnson Innovative Medicine
What is Christopher Callas's role at the current company?
Christopher Callas's current role is Associate Scientist II, Global Discovery Chemistry.
What schools did Christopher Callas attend?
Christopher Callas attended University Of Chicago, Temple University, Universidad De Oviedo, Jenkintown High School.
Who are Christopher Callas's colleagues?
Christopher Callas's colleagues are Joana Moraes, Johan Snitjer, Jan Peterson, Bruce Beardsell, Soniya Pandey, Emmanuel De Jesús Morales, Jesús Linares.
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Christopher Callas
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Christopher Callas
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