Chris Henderson Email & Phone Number

Cambridge, England, United Kingdom

Contributed to the strategic vision for all automation workflows across Scientific Operations, engaging with key stakeholders to initiate projects and fully managing their implementation. - Design and currently implementing an automated cell culture platform for CRISPR screening for the ten-year MAVE-SGE project. This has included utilitising existing on-site equipment. - Creation of a standardised Hamilton Venus training framework that has been rolled out across the team. -… Show more Contributed to the strategic vision for all automation workflows across Scientific Operations, engaging with key stakeholders to initiate projects and fully managing their implementation. - Design and currently implementing an automated cell culture platform for CRISPR screening for the ten-year MAVE-SGE project. This has included utilitising existing on-site equipment. - Creation of a standardised Hamilton Venus training framework that has been rolled out across the team. - Fostered collaboration across Scientific Operations, ensuring automation support is available to everyone. Show less

Cambridge, England, United Kingdom

- Identified solutions that enabled the integration of high throughput and traditional bench-scale systems- Validation of automation solutions through data generation - Asset Utilization of automated platforms- Production of standardised scripting across liquid handling platforms- Training of Scientists and other Automation Experts across a range of systems- 3D CAD design and printing- Outreach and educational visits- "First responder" to critical equipment breakdowns

Cambridge, England, United Kingdom

Cambridge, United Kingdom

I have automated a high-throughput DNA and protein purification platform capable of producing 500 high-quality proteins weekly. These are then used to optimise biological candidate drugs across all therapy areas as well as provide data for predictive protein expression. To do this, I worked closely with scientists to program methods onto multiple liquid handlers to produce a highly automated platform.

Sheffield Rnai Screening Facility, Centre For Membrane Interactions And Dynamics

The project focused on elucidating the intracellular signalling pathway used by a synthetic prostaglandin in human airway epithelial cells to trigger chloride secretion. This has encompassed submission of a research proposal; summarising the field and potential avenues of further research, six months of independent benchwork into the precise pathway utilised by this compound, and a poster presentation of my results to industry and academic specialists. Due to the nature of my experiments and… Show more The project focused on elucidating the intracellular signalling pathway used by a synthetic prostaglandin in human airway epithelial cells to trigger chloride secretion. This has encompassed submission of a research proposal; summarising the field and potential avenues of further research, six months of independent benchwork into the precise pathway utilised by this compound, and a poster presentation of my results to industry and academic specialists. Due to the nature of my experiments and research, I developed excellent time-management skills, and the commitment to carry on through challenges. Show less

Department Of Sensory Physiology

I investigated the role of a transcription factor in organogenesis of the mouse inner ear through modulation of intracellular pathways. This project incorporated a literature review, three months of independent laboratory research and an oral presentation to academics. Throughout this project I was constantly critically assessing experimental designs as to improve the quality and efficiency of my work, and undertaking independent research goals that I designed.

Cell Biology & Cancer Facility, Department Of Infection & Cardovascular Disease

Separate to my studies, I independently organised two summer placements; gaining first-hand experience in academic research and QC. While there, I optimised an immunolabelling practical class, investigated the possibility of replacing the standard cell line and produced an antibody stock. I was also hands-on with model organisms, investigating inflammation in zebrafish.