Management of GPCR and neuroscience drug discovery collaboration between the Monash Institute of Pharmaceutical Sciences and Servier Laboratories

Position as Head of Pharmacology at Heptares Therapeutics to work on GPCR targets using structure-based drug discovery approaches, with the company's unique access to x-ray crystallography data of GPCR targets and StaR technology.Responsible for in vitro and in vivo pharmacology and ADMET at all stages of drug discovery up to clincal candidate selection. I manage internal team of scientists plus outsourced studies through a global network of CROs.

Lecturer on Drug Discovery for NST IB and II students

Leader of a Biochemical Pharmacology team responsible for validation of novel targets for depression & anxiety, bipolar disorder and schizophrenia. Use of compound and RNAi-based approaches in combination with in vitro pharmacological and biochemical techniques in recombinant, primary and stem cell lines and native tissue to characterise a diverse array of targets in the early psychiatry portfolio. Leadership of drug discovery programmes at all stages of the preclinical portfolio;… Show more Leader of a Biochemical Pharmacology team responsible for validation of novel targets for depression & anxiety, bipolar disorder and schizophrenia. Use of compound and RNAi-based approaches in combination with in vitro pharmacological and biochemical techniques in recombinant, primary and stem cell lines and native tissue to characterise a diverse array of targets in the early psychiatry portfolio. Leadership of drug discovery programmes at all stages of the preclinical portfolio; extensive experience of disciplines across the industrial drug discovery matrix. Show less

Co-ordinate and perform wide range of in vitro and ex vivo pharmacological techniques to support ongoing gene to target, target to lead and lead optimisation programmes for schizophrenia and bipolar disorder.Extensive experience in the use of molecular pharmacology / biology techniques to augment the drug discovery process. Key contact for data analysis and quantitative pharmacology.