Supporting large-scale, Population Genomics programmes globally, assisting in the design & implementation of clinical, ultra-high throughput sequencing environments required to achieve utilisation of NGS within healthcare/clinical environments via use of reference architectures & backbone infrastructure. Facilitating partnership engagement & development between KOLs, healthcare, industry & best in class service providers.

As a Senior Project Application Scientist within Illumina’s EMEA Commercial group, I utilise extensive knowledge and experience gained through project managing the Genomics England/UCAM projects at Illumina to provide & develop support and consultative services for leading whole-genome sequencing centres across the EMEA (Europe, Middle East & Africa) region. I am responsible for developing, communicating and effectively executing the highest level of commercial support with key opinion leaders. I serve as a technical consultant and implementation liaison with technical experts (internal or external) in the development, implementation and efficient running of sequencing programs, from facility planning to technical validation and training, driving strategic support planning activities via project management, and managing execution of support deliverables involved in large, complex client consultations and implementation projects.

I effectively managed & maintained the high profile Genomics England/UCAM project, utilising whole genome sequencing (WGS) in a healthcare environment, helping create a lasting legacy for patients, the NHS and the UK economy through the sequencing of 100,000 genomes from 70,000 people with rare genetic diseases, plus their families & patients with cancer. The aim is to transform care by creating a new genomic medicine service for the NHS. This project is a world first; a partnership between NHS England, the Department of Health, Genomics England, University of Cambridge & Illumina. This collaborative approach will enable ground-breaking medical research, combining genomic sequence data with medical records. Causes, diagnosis & treatment of diseases will be investigated, & the interpretation of data optimised to help patients, paving the way for the personalised medicine by using genomics within the healthcare environment. Integral member of the management & management review team for the implementation of ISO 15189 into Illumina’s clinical sequencing laboratory. Implementing quality improvement activities identified through internal audit & management review. Heavily involved in writing new SOP’s, work instructions & managing the control of laboratory documents. I manage the training & maintenance of competency records for the multidisciplinary laboratory team.Implementation of the NC/CAPA procedure & identification of non-conforming results & subsequent corrective/preventative actions.

I was a sequencing Production Research Associate working on a number of technical platforms responsible for the entire pipeline for DNA sequencing, including generation of libraries, sample enrichment and operation of NGS platforms. I liaised with and discussed sample preparation, experimental design and progress with collaborating groups, advised and assisted Research assistants and technicians, and assisted the Laboratory Manager in ensuring the smooth running of the CGR, troubleshooting technical problems as they arose, and optimising protocols.

Sequencing specialist providing NGS & Sanger sequencing for the CRUK Cambridge Research Institute (CRI). My role included sample handling and preparation for high throughput short- read NGS, flow cell creation on Illumina’s Cluster Station, PCR and gel electrophoresis. As one of two sequencing specialists I provided consultation/training, troubleshooting and protocol optimisation for sequencing techniques and analysis to over 300 scientists at CRI. Within the role I proved my adaptability and capacity for learning new techniques and skills, exploring and expanding the use of new sequencing technologies.

Member of an ion channel R&D team developing and executing efficient target driven, drug discovery assays and analysis. Experience: cell culturing (HEK and CHO cells), fluorescent imaging plate reader technology, spectrophotometry, liquid chromatography, LIMS and GLP.

High throughput cat 3 laboratory examining bovine tissue for indicators of BSE. Experience included ELISA, LIMS, verification of peers’ results, high standards of maintenance and adherence to strict safety and assurance systems, SOPs, GLP and analytical quality control.

(12 week contract). Detailed knowledge of GLP, SOPs, specialist equipment and compound management databases.