Consultant, Biologics Drug Discovery And Antibody Engineering
Self-Employed
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Christilyn Graff Email & Phone Number
Consultant, Biologics Drug Discovery and Antibody Engineering
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Self-employed
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Role
Consultant, Biologics Drug Discovery and Antibody Engineering
Location
Boulder, Colorado, United States
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Christilyn Graff is listed as Consultant, Biologics Drug Discovery and Antibody Engineering at Self-employed, based in Boulder, Colorado, United States. AeroLeads shows a matched LinkedIn profile for Christilyn Graff.
Christilyn Graff previously worked as Senior Vice President, Head of Research at Mosaic Biosciences and Consultant, Biologics Drug Discovery & Antibody Engineering at Self-Employed. Christilyn Graff holds Phd, Chemical Engineering from Massachusetts Institute Of Technology.
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Profile bio
About Christilyn Graff
I am a Biotech leader passionate about developing people, teams, and drugs. Over two decades, I have built a reputation for integrating key insights from diverse experience as a bench scientist, project leader, and leadership team member to cultivate talent, optimize lab processes and data utilization, and improve the teaming ecosystem.Developing People and the Next Generation of Leaders: Mentored and developed scientists across all levels, from Associate Scientist to Director. Created internal pipeline of employees equipped to increase impact across portfolio projects, technology initiatives, and project leadership while recruiting high-performing individuals. R&D representative to companywide temporary work assignment program.Developing Teams and Influencing Company Culture: Leader and key contributor to Discovery Research and R&D-wide initiatives. Recognized for creating strong team culture, sense of community, and diverse coalitions to advance initiatives. Championed, designed, and co-taught pilot training series for all R&D employees focused on embedding skills, tools, and actions of high-performing teams in all members. Member of R&D DEI committee, leading efforts focused on identifying barriers and addressing obstacles to increase inclusion and access to opportunities.Developing Drugs and Advancing Technology: Extensive history working on the cutting edge of antibody engineering technologies, implementing strategies to accelerate discovery and optimization of high-quality, developable therapeutic candidates. Recognized for working on established biological pathways, as well as novel biology, encompassing therapeutic areas including oncology, neurology, immunology, hemophilia, and fibrosis. Championed and led efforts to advance new technology platforms and manage and extract value from data.
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11 roles
Christilyn Graff work experience
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Senior Vice President, Head Of Research
Current
Sep 2024 - Present
Consultant, Biologics Drug Discovery & Antibody Engineering
Current
Self-Employed
Jan 2024 - Present
Senior Director, Antibody Discovery & Early Portfolio Lead
Promoted to lead the early biologics portfolio, I accelerated decision-making to advance assets through Discovery Research. Built teams to partner cross-functionally, fostering a culture of collaboration. A pivotal initiative I championed involved investing in data pipelining capabilities within Discovery Research, which encompassed data management to facilitate the empowerment of machine learning models. Leading a team of 20 (direct and indirect), I oversaw this initiative from its inception through technology landscaping, project approval, and kickoff, driving innovation and efficiency within the organization.
Dec 2021 - Oct 2023
Interim Head, Tissue Enhanced Delivery Technologies
Selected to spearhead a critical phase of growth within Biologics Drug Discovery, leading our team through a comprehensive rebuild. With a focus on systemic central nervous system (CNS) delivery of multiple modalities, I provided strategic oversight to a 30-person cross-functional team, advancing efforts on established and novel receptor-mediated transcytosis (RMT) shuttles. Empowering scientists within the team led to more transparent prioritization of activities and a notable increase in our speed to address critical questions.
Jul 2021 - Jul 2022
Director, Antibody Discovery And Engineering
As the Head of Antibody Platforms, I drove strategic partnerships with external partners and oversaw a highly effective internal antibody discovery and optimization team. I evaluated technologies, negotiated high-value deals, performed due diligence on in-licensed antibody programs, forecasted financial milestones, and led investments in data pipelining, enabling machine learning models.
Jun 2018 - Dec 2021
R&D Project Leader
Nominated for seven-person cohort to pilot a new R&D project leader (RDPL) model for all projects in the R&D portfolio. Member of first RDPL council (peer-elected) and inaugural RDPL Council Chair. As Council Chair, I was a member of the extended R&D leadership team (RDLT) to represent the RDPL community, highlighting areas for optimization and acting as a bi-directional conduit of information between the RDLT and project leaders. Led multiple process improvements over the lifetime of the RDPL model (2017-2023), returning to the RDPL Council in 2023 to provide direction and continuity amidst changes in the project leader development and support model.
Jan 2017 - Apr 2019
Principal Scientist
Expansive set of responsibilities focused on antibody platform and technology management, project leadership, and partner alliance management. Notable achievements include launching and optimizing a Laboratory Information Management System (LIMS) to track data for in vitro antibody platforms, leading drug discovery efforts (project co-lead) for a biologics program targeting long-lived plasma cells, and serving as R&D Project Leader for a fibrosis program from inception to strategic wind-down. Additionally, I was the lead Biologics representative supporting spin out of the hemophilia antibody portfolio to Bioverativ, including oversight of scientific and business development matters.
Aug 2012 - Jun 2018
Senior Scientist
Directed expansion of internal efforts on in vitro antibody platforms, high-throughput automation, and protein analytics at two R&D sites. Designed and executed refresh of antibody platform technology through a competitive evaluation process, leading team that recommended in-licensing of Adimab platform in 2013.
Aug 2008 - Aug 2012
Scientist Ii
In my role as Antibody Display Group Lead for the IGF1R project, I oversaw the discovery of BIIB022 and successfully delivered the antibody within the shortest internal timeframe from project inception to First Patient In (FPI). Additionally, as the Antibody Display Group Lead for the Lingo-1 project, I led the discovery and optimization efforts resulting in BIIB033/Opicinumab. This achievement established a robust antibody set for foundational research in a novel pathway.
Feb 2005 - Aug 2008
Scientist I
Hired as scientific lead for phage display external alliances and internal in vitro antibody platforms. Alliance manager and JRC member for MorphoSys collaboration. Led efforts to evaluate alternative in vitro platforms, resulting in adoption of Dyax antibody platform.
Sep 2002 - Feb 2005
3 education records
Christilyn Graff education
Phd, Chemical Engineering
Massachusetts Institute Of Technology
Ms, Chemical Engineering
University Of Illinois Urbana-Champaign
Bs, Chemical Engineering
The University Of Texas At Austin
FAQ
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What company does Christilyn Graff work for?
Christilyn Graff works for Self-employed.
What is Christilyn Graff's role at Self-employed?
Christilyn Graff is listed as Consultant, Biologics Drug Discovery and Antibody Engineering at Self-employed.
Where is Christilyn Graff based?
Christilyn Graff is based in Boulder, Colorado, United States while working with Self-employed.
What companies has Christilyn Graff worked for?
Christilyn Graff has worked for Self-Employed, Mosaic Biosciences, and Biogen.
How can I contact Christilyn Graff?
You can use AeroLeads to view verified contact signals for Christilyn Graff at Self-employed, including work email, phone, and LinkedIn data when available.
What schools did Christilyn Graff attend?
Christilyn Graff holds Phd, Chemical Engineering from Massachusetts Institute Of Technology.
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