Christine (Couch) Kestner, Phd, Ms Email and Phone Number
I am a dedicated immunologist and neuroscientist with over eight years of experience specializing in oncology, immunology, neuroscience, and cardiovascular surgery. My background encompasses advanced laboratory techniques, strategic research design, and innovative therapeutic development, demonstrating a commitment to driving scientific progress and delivering impactful results.Professional Highlights:Research Leadership: Spearheaded advanced investigations into novel therapeutic targets for pancreatic cancer and acute myeloid leukemia (AML), leading to the identification of drug candidates and the enhancement of treatment regimens through molecular screening and high-throughput assays.Innovative Development: Engineered DNA vectors for antibody and protein expression, contributing to the discovery of actionable drug candidates and advancing both preclinical research and therapeutic development.Advanced Methodologies: Established novel cell lines for studying mesothelin’s role in cancer, optimizing models for targeted therapy and drug screening. Applied sophisticated techniques in protein expression, purification, and biophysical characterization to enhance research efficiency and throughput.High-Impact Communication: Delivered influential presentations and authored peer-reviewed publications, effectively conveying complex research findings and contributing to scholarly discourse.Core Competencies:Technical Proficiency: PCR, ELISA, IHC + ICC, Cell Culture, Microscopy, Immunoassays, Animal Models, Flow Cytometry, Western Blotting, Molecular CloningLeadership & Management: Project Management, Team Collaboration, Strategic Planning, Problem Solving, Public Speaking, MentoringCareer Aspirations:I am actively seeking opportunities in the biopharmaceutical sector where I can apply my expertise to advance cutting-edge therapeutics and optimize research processes. My objective is to drive innovation through rigorous research, collaborative efforts, and strategic leadership, contributing to the development of transformative treatments.I am enthusiastic about connecting with industry professionals and organizations focused on advancing medical science and enhancing therapeutic solutions.
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Neuroscience Expert And Content ConsultantLivenCharleston, Sc, Us
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Founder | Science Writer + CommunicatorBrain And BeyondCharleston, Sc, Us
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TutorGrade Potential Tutoring Oct 2024 - PresentAs a science and math tutor, I tailor lesson plans for students needing extra support in biology, algebra, chemistry, biochemistry, and neuroscience. Using interactive teaching tools and focusing on student-specific needs, I help them achieve an average 20% grade increase and build their confidence and mastery in challenging subjects. -
Postdoctoral ScholarMedical University Of South Carolina Aug 2023 - Sep 2024-Led research on therapeutic targets like mesothelin for pancreatic cancer and acute myeloid leukemia, evaluating the anti-tumor efficacy and mechanisms of action of novel antibody therapies; contributed to preclinical studies that identified promising candidates for further drug development.-Mastered and applied advanced skills in protein therapeutic design, production, purification, and evaluation in preclinical cancer models; conducted research across the drug development pipeline from high-throughput screening and lead optimization to early toxicology, driving progress toward potential clinical applications. -
Graduate Research AssistantMedical University Of South Carolina May 2019 - May 2023-Led research investigating the role of the complement system in neuroinflammation and neurodegeneration following brain injuries like stroke and traumatic brain injury (TBI); focused on understanding the complement-microglial axis in neuronal and synaptic loss, contributing to insights into neurodegenerative mechanisms and repair pathways.-Assessed the relationship between inflammatory biomarkers and rehabilitation outcomes in ischemic stroke patients, providing evidence for biomarkers as potential indicators of functional recovery.-Explored the impact of comorbidities such as aging and cigarette smoking on acute post-stroke outcomes; demonstrated that complement inhibition could mitigate neuroinflammatory responses and improve recovery in affected populations.
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Cardiothoracic Surgery Research ManagerMedical University Of South Carolina Jul 2017 - May 2019Charleston, South Carolina Area-Led and coordinated research projects in a cardiothoracic surgery lab focused on understanding cardiovascular diseases such as thoracic aortic aneurysms, myocardial infarction, and arrhythmias; managed experimental design and execution, resulting in valuable insights into disease mechanisms and potential therapeutic approaches.-Trained and mentored research staff, interns, and medical students while overseeing daily lab operations, equipment maintenance, and project timelines, ensuring smooth workflows and successful completion of studies in a high-paced research environment.
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Research Specialist IiMedical University Of South Carolina May 2014 - Jul 2017Charleston, South Carolina Area-Investigated the electrophysiology of healthy, diseased, and stem cell-derived cardiac cells; designed and executed experiments using advanced electrophysiological techniques, leading to a deeper understanding of cardiac cell behavior and potential therapeutic targets.-Collaborated on projects studying the electrical signaling pathways in various cardiac cell types, analyzing data to uncover key differences between healthy and pathological conditions, and contributing to ongoing research to improve cardiac health outcomes.
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Math And Science TutorTlc Total Learning Concepts May 2013 - May 2014Lilburn, Georgia-Developed personalized tutoring strategies for high school students in subjects including Algebra 2, Geometry, Statistics, Pre-Calculus, Trigonometry, Biology, Chemistry, Anatomy, and Physics, as well as SAT and ACT preparation; identified learning gaps and tailored teaching methods, leading to a 50% improvement in grades and higher standardized test scores. -
High School Varsity Tennis CoachGreater Atlanta Christian School Jan 2012 - May 2013Norcross, Georgia
Christine (Couch) Kestner, Phd, Ms Education Details
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Doctor Of Philosophy - Phd
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Cell/Cellular And Molecular Biology -
Biology
Frequently Asked Questions about Christine (Couch) Kestner, Phd, Ms
What company does Christine (Couch) Kestner, Phd, Ms work for?
Christine (Couch) Kestner, Phd, Ms works for Liven
What is Christine (Couch) Kestner, Phd, Ms's role at the current company?
Christine (Couch) Kestner, Phd, Ms's current role is Neuroscience Expert and Content Consultant.
What schools did Christine (Couch) Kestner, Phd, Ms attend?
Christine (Couch) Kestner, Phd, Ms attended Medical University Of South Carolina, Georgia State University, University Of South Carolina.
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