Christopher Benner Email & Phone Number
@ucsd.edu
1 phone found area 858
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Who is Christopher Benner? Overview
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Christopher Benner is listed as Associate Professor at UC San Diego, a company with 31563 employees, based in San Diego County, California, United States. AeroLeads shows a work email signal at ucsd.edu, phone signal with area code 858, and a matched LinkedIn profile for Christopher Benner.
Christopher Benner previously worked as Assistant Professor at Uc San Diego and Director of Integrative Genomics Core at Salk Institute For Biological Studies. Christopher Benner holds Phd, Bioinformatics from Ucsd.
Email format at UC San Diego
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About Christopher Benner
I am a bioinformatics and genomics scientist fascinated by how our cells decode the regulatory DNA in our genome to orchestrate transcriptional responses. My laboratory develops computational and experimental technologies to study how transcription is regulated, analyzing how regulatory DNA, transcription, epigenetics, and 3D genome structure exert influence on one another. The laboratory leverages experimental methods to profile transcription initiation in the genome (e.g. csRNA-seq, TSS-MPRA), which provide sensitive measurements of regulatory element activity at single-nucleotide resolution. The unique properties of these approaches are then used to model how transcriptional networks respond to inflammatory stimuli or other pathological conditions and monitor the impact that non-coding genetic variation plays in perturbing transcriptional responses. The laboratory also collaborates with multiple groups to study viral host-pathogen interactions, cellular development, chronic inflammatory diseases, and substance abuse. We also continue to develop genomics software, exemplified by HOMER and the pathway enrichment tool Metascape, that can be leveraged by the scientific community to improve the interpretation of genomics data.
Listed skills include C++, C, Perl, Java, and 16 others.
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Christopher Benner work experience
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Associate Professor
Current
Assistant Professor
Director Of Integrative Genomics Core
Assistant Project Scientist
- Lead analyst for genomics/nextgen-sequencing assays for multiple, diverse laboratories.
- Creating analysis tools to study 3D-genome architecture using Hi-C.
- Developing novel sequencing strategies and analysis techniques to study mechanisms of transcription inititation at enhancers (eRNAs).
- Investigating mechanisms by which genetic variation causes changes in transcription factor localization and epigenetic states in both mouse strains and human individuals.
- Establishing analysis methodology and a software package for large-scale sequencing projects: http://biowhat.ucsd.edu/homer/
Postdoctoral Researcher
- Developed analysis techniques for the discovery of enhancer-associated RNAs (eRNAs).
- Uncovered relationships between collections of transcription factors and chromatin modifications that establish cell type-specific enhancer networks.
- Worked closely with research scientists and principle investigators to develop experimental design, optimize data quality, and interpret results.
- Performed extensive analysis of publicly available sequencing data to cross-validate concepts.
Bioinformatics Graduate Research Assistant
- Conducted dissertation research on DNA regulatory elements and their roles in transcription.
- Developed a novel motif discovery algorithm optimized for high-throughput data from complex genomes.
- Integrated RNA-Seq, MNase-Seq, and ChIP-Seq data to identify novel elements and key architectural features of promoters at nucleotide resolution.
- Created library of transcription start sites in over 70 organisms and identified conserved regulatory elements and promoter features.
- Used expression profiles from both patients and disease models to identify regulatory elements activated in specific inflammatory diseases.
Cheminformatics/Bioinformatics Intern
- Used machine learning (SVMs) to predict activity and drug-likeness of compounds from structural keys to prioritize and expand compound libraries for high-throughput screening.
- Developed a novel clustering algorithm for gene expression data that assessed cluster confidence by propagating variance in gene expression measurements.
Christopher Benner education
Frequently asked questions about Christopher Benner
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What company does Christopher Benner work for?
Christopher Benner works for UC San Diego.
What is Christopher Benner's role at UC San Diego?
Christopher Benner is listed as Associate Professor at UC San Diego.
What is Christopher Benner's email address?
AeroLeads has found 1 work email signal at @ucsd.edu for Christopher Benner at UC San Diego.
What is Christopher Benner's phone number?
AeroLeads has found 1 phone signal(s) with area code 858 for Christopher Benner at UC San Diego.
Where is Christopher Benner based?
Christopher Benner is based in San Diego County, California, United States while working with UC San Diego.
What companies has Christopher Benner worked for?
Christopher Benner has worked for Uc San Diego, Salk Institute For Biological Studies, and Gnf.
How can I contact Christopher Benner?
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What schools did Christopher Benner attend?
Christopher Benner holds Phd, Bioinformatics from Ucsd.
What skills is Christopher Benner known for?
Christopher Benner is listed with skills including C++, C, Perl, Java, Html, Sql, Next Gen Sequencing Analysis, and Unix Administration.
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