Christopher Bennett Email & Phone Number

Cambridge, Massachusetts, United States

Cambridge, Massachusetts, United States

• Focused research efforts on the identification of pharmacological approaches to either i) mitigate cellular damage from mitochondrial disease mutations or ii) boost mitochondrial function through assembly of.
• Developed a protein-protein interaction biosensor to measure mitochondrial respiratory supercomplex formation
• Completed a high-throughput chemical screen to elucidate novel modulators of mitochondrial respiratory supercomplex assembly and bioenergetics. This work uncovered a targetable phospholipid synthesis pathway important.
• Identified pharmacological suppressors of mitochondrial disease mutations including tetracycline antibiotics that exert neuroprotective effects in a Leigh syndrome mouse model

Doctor Of Philosophy (Phd), Molecular And Cellular Biology

Researched the interaction between mitochondrial dysfunction and longevity control. Identified hormetic responses that mitigate cellular.

Bachelor Of Science (Bs), Biochemistry

• Participated in research projects to study cap-binding proteins in mRNA translational control • Performed protein binding interactions.