Christopher Byrne Email & Phone Number

Royal College Of Surgeons In Ireland.

• Management and administration of Research Institute initiatives such as seed funding calls and funding for research equipment and infrastructure. • Management of the Research Institute capital and recurrent budget.• Planning of new research infrastructure and/or refurbishment plans.• Preparing institutional research reports and coordinating institutional research reviews, quality reviews and site visits. • Development and implementation the institute's research dissemination strategy, including research events, annual reports, website content and social media.• Organisation of annual RCSI Research Day conference.• Animal Welfare Body committee member.

Earlsford Terrace Dublin 2

Scientific Animal Protection.• Conducted scientific evaluation of data submitted in support of applications to carry out research involving animals• Prepared of assessment reports to communicate assessment findings to stakeholders• First point of contact and provided technical information to applicants, regulatory authorities, industry and other relevant stakeholders.

Royal College Of Surgeons Ireland

• Directed the Department of Surgery's research program to align with major funding bodies priorities. • Designed and carried out retrospective clinical trials testing a number of breast cancer associated biomarkers.• Liaised with industrial partners and other stakeholders on the commercialization of the department’s intellectual property.• Wrote and managed a translational grant proposal• Prepared and delivered lectures and tutorials for undergraduate medicine in breast cancer research at RCSI Bahrain (Jan 2015).

Endocrine Oncology Research, Dept Of Surgery

5 years experience in the Surgery department where translational research is used to develop novel therapies and drug regimens to overcome resistance in breast cancer. Duties included: • Data collection, critical analysis and presentation of results from clinical research programs. • Managed three successful grant applications: SFI (TIDA), HRB Health Research Award and EU FP7 (Industrial and Academic Partnership).• Preparation and writing of journal manuscripts for high impact publication.• Filed a patent to protect and commercialise my research (details on request)• Supervised and mentored undergraduate, PhD and MD students• Prepared and delivered lectures and tutorials for undergraduate and HRB PhD program.In addition, I help supervise the work of undergraduate and post graduate students and give tutorials.• Trained in quality and compliance regulations of the pharmaceutical industry • Developed collaborative links between RCSI and the Almac group.

A collaborative research project between the school of pharmacy and Almac Discovery to elucidate the biological mechanism of the novel anti-angiogenic drug ALM201.• Prepared data and reports to industry standards• Presented at the monthly meeting between the groups where progress was discussed.• Techniques mainly involved cell culture, Western blotting and Real Time pcr.

Molecular Therapeutics, School Of Pharmacy.

I successfully completed my PhD entitled: “The role of the novel protein FKBPL in hormone receptor complexes and implications for breast cancer growth, survival and response to current therapies”. Techniques used have included cell culture, gene cloning, transfection, siRNA gene knockdown, radiation, clonogenic assay, growth curves, real time PCR, western blotting, cell signalling, phospho-proteins, co-immunoprecipitation, immunocytochemistry, confocal microscopy.This work resulted in the publication of a patent to protect the valuable IP generated and the results were published in Cancer Research in Feb 2010:FKBPL regulates estrogen receptor signaling and determines response to endocrine therapy.McKeen HD*, Byrne C*, Jithesh PV, Donley C, Valentine A, Yakkundi A, O'Rourke M, Swanton C, McCarthy HO, Hirst DG, Robson T.Cancer Res. 2010 Feb 1;70(3):1090-100. Epub 2010 Jan 26.*Joint first author

Doctor Of Philosophy - Phd, Molecular Therapeutics

“The role of the novel protein FKBPL in hormone receptor complexes and implications for breast cancer growth, survival and response.

Msc, Bioinformatics

Bsc, Biochemistry

Activities and Societies: I was the biochemistry class representative in our final year 2000/2001.