Christopher Duhyun Han Email & Phone Number

Toronto, Ontario, Canada

Toronto, Ontario, Canada

• Procure reagents, supplies and equipment for the research and commercial labs & keep expenditures within the operations budgets through routine supplier price monitoring.• Design & build a cloud-based QMS compliant with international biobank QMS standards (ISO 9001 & 20387) which can track 200+ quality documents & records such as biobank procedures, equipment certificates and batch records. • Write & review 50+ SOPs for the customer hair follicle cryopreservation process, ISO 7… Show more • Procure reagents, supplies and equipment for the research and commercial labs & keep expenditures within the operations budgets through routine supplier price monitoring.• Design & build a cloud-based QMS compliant with international biobank QMS standards (ISO 9001 & 20387) which can track 200+ quality documents & records such as biobank procedures, equipment certificates and batch records. • Write & review 50+ SOPs for the customer hair follicle cryopreservation process, ISO 7 cleanroom maintenance and cold chain logistics to optimize the procedures and consistently provide high quality services to customers.• Prepare and ship temperature-sensitive perishable items including hair follicle samples packaged with phase-changing materials as well as frozen cell or protein vials in dry ice without delays.• Perform collection, cryobanking, and viability analysis of customer hair follicles following the most up-to-date SOPs while documenting the entire process in batch records. • Design cryopreservation validation plan and analyze validation data.• Analyze the customer sample freezing process and introduce a new sample tracking system and an extra layer of sample protection that reduced the sample processing time by 20% while ensuring the quality of over 500 samples. • Optimize in vitro conditions for extraction and expansion of various stem cells from human hair follicles.• Conduct root-cause analyses on the processing facility audit findings and establish CAPA plans to improve the quality of Acorn’s services and the QMS. Identified problems in the document control procedures and validation processes. • Develop and optimize human tissue viability assays, cryopreservation process and process validation methods. Show less

Toronto, Ontario, Canada

• Liaised with various departments within the research institute, vendors, and collaborators to secure resources for 15+ ongoing projects without any delays. • Wrote & reviewed standard operating procedures; ensured compliance with all laboratory policies, WHIMIS standards and government regulations; and eliminated potential hazards within the laboratory.• Designed and executed experiments to discover potential therapeutics for a liver disease using C. elegans.• Maintained a… Show more • Liaised with various departments within the research institute, vendors, and collaborators to secure resources for 15+ ongoing projects without any delays. • Wrote & reviewed standard operating procedures; ensured compliance with all laboratory policies, WHIMIS standards and government regulations; and eliminated potential hazards within the laboratory.• Designed and executed experiments to discover potential therapeutics for a liver disease using C. elegans.• Maintained a mammalian cell line (HEK293T); cloned, extracted & transfected plasmids; and designed and performed in vitro viability assays. • Implemented an Excel-based chemical stock tracking system that minimized the time spent on search for chemicals in small vials by 80%, allowing the researchers to begin their experiments promptly. • Create Purchase Orders to procure daily lab supplies and scientific equipment from external vendors while tracking budgets to keep the expenditures below the monthly limit. • Prepared and maintained appropriate documents for biosafety and chemical safety inspections as well as financial audits. • Taught new graduate students how to design experiments & use lab equipment; optimize equipment settings for students’ experiments; and advise them on troubleshooting process. Show less

Toronto, Ontario, Canada

• Drafted medical case reports that concisely described the unique symptoms of patients with severe allergic diseases, rationales for the initiation of antibody therapies, prognosis of the patients and the potential underlying cause of it.• Created a searchable database of pre-seasonal allergic rhinitis patients based on their symptoms, allergens and/or medications they were on using Microsoft Access.• Prepared and submitted an ethics application for a case study to the St. Michael’s… Show more • Drafted medical case reports that concisely described the unique symptoms of patients with severe allergic diseases, rationales for the initiation of antibody therapies, prognosis of the patients and the potential underlying cause of it.• Created a searchable database of pre-seasonal allergic rhinitis patients based on their symptoms, allergens and/or medications they were on using Microsoft Access.• Prepared and submitted an ethics application for a case study to the St. Michael’s Hospital ethics committee.• Translated 10 patient handouts on allergy & asthma symptoms and care from English to Korean. Show less

Toronto, Ontario, Canada

PCL469 Systems Pharmacology I• Led small case-study group discussions to help students identify the cause of symptoms and review the advantages and disadvantages of each drug in a fourth-year pharmacology course. • Kept students engaged in the discussions by asking improvised questions, telling trivia facts on some drugs, and providing hints when students were struggling.• Advised students seeking help or willing to continue the discussion after class both in-person and via… Show more PCL469 Systems Pharmacology I• Led small case-study group discussions to help students identify the cause of symptoms and review the advantages and disadvantages of each drug in a fourth-year pharmacology course. • Kept students engaged in the discussions by asking improvised questions, telling trivia facts on some drugs, and providing hints when students were struggling.• Advised students seeking help or willing to continue the discussion after class both in-person and via email. • Implemented a new quiz system following the course coordinator’s instruction and provided feedback to improve the students’ learning experience. Show less

Toronto, Ontario, Canada

▪ Maintained prostate cancer cell lines and extracted proteins for western blot analysis.▪ Performed survival assays and scratch assays to compare the viability and migration potentialbetween prostate cancer cell lines with or without circular RNA overexpression un der starvedconditions.▪ Identified several candidate proteins that might be part of a circular RNA signal pathway viawestern blots with SDS-PAGE.▪ Conducted literature review on recent advances in circular RNA… Show more ▪ Maintained prostate cancer cell lines and extracted proteins for western blot analysis.▪ Performed survival assays and scratch assays to compare the viability and migration potentialbetween prostate cancer cell lines with or without circular RNA overexpression un der starvedconditions.▪ Identified several candidate proteins that might be part of a circular RNA signal pathway viawestern blots with SDS-PAGE.▪ Conducted literature review on recent advances in circular RNA research through PubMed and wrote clear and thorough reports on the project Show less

Hong Kong Sar

▪ Thoroughly evaluated the chemotherapy sensitizing effect of a novel protein phosphatase A2inhibitor on in vitro & in vivo gastric cancer models.▪ Performed cell proliferation assays (MTT & colony formation), apoptosis assay, and G2/M cell cycle assay for in vitro analysis.▪ Measured the size of all tumors of mice xenograft models and extracted RNA & proteinsfrom each tumor for further experiments.▪ Utilized various software such as Image J, Mi crosoft Excel, and GraphPad… Show more ▪ Thoroughly evaluated the chemotherapy sensitizing effect of a novel protein phosphatase A2inhibitor on in vitro & in vivo gastric cancer models.▪ Performed cell proliferation assays (MTT & colony formation), apoptosis assay, and G2/M cell cycle assay for in vitro analysis.▪ Measured the size of all tumors of mice xenograft models and extracted RNA & proteinsfrom each tumor for further experiments.▪ Utilized various software such as Image J, Mi crosoft Excel, and GraphPad Prism to analyze cellcolony formation data, generate graphs, and perform T tests.▪ Learned various molecular and cellular techniques including PCR, Ki67 immunohistochemistry, wound healing assay in dedicated tutorial sessions. Show less

Markham, Ontario, Canada

Master Of Science (M.Sc.), Pharmacology

Honours Bachelor Of Science (Hon.B.Sc.), Pharmacology & Human Biology