Christopher Ecker Email & Phone Number

Los Angeles, CA, US

San Diego, California, US

• Led team that performed in vitro and in vivo screens to identify lead candidate CAR configuration for undisclosed solid-tumor target.
• Led team that initiated 2 novel discovery projects to enhance iPSC-CAR T resistance to solid TME and fratricide.
• Manage full-time responsibilities for 4 reports (1 PhD level scientist, 2 AS, and 1 SRA.)
• Discovery efforts led to 1 provisional patent filing and use in next-generation clinical stage asset.

Santa Monica, California, US

• Developed pre-clinical assets that augment clinical efficacy or safety of primary CD19 CAR T via small molecules or genetic engineering that led to 1 patent filing.
• Executed 2 screens exploring effects of 2,000 small molecules and 20 transcription factors on primary CAR T functionality.
• Partnered in multiple internal cross-functional collaborations between PD, Translational Medicine, and R&D.
• Generated strategies for Chronic Lymphocytic leukemia and indication-specific research strategies for next generation CAR T programs.
• Manage full-time responsibilities of 3 senior research associates.

Philadelphia, PA, US

Thesis Mentor: James Riley, PhDPrimary Project: Identification of metabolic salvage pathways that human T cells rely on in limiting nutrient environments and how their adaptation affects their subsequent immune function. Secondary Project: Examining how mitochondrial morphology and function is altered upon T cell activation.Rotation Project: Development.

Doctor Of Philosophy - Phd, Immunology

Bachelor Of Science - Bs, Biology, General