Christopher Larywon Email & Phone Number

• Screened drug candidates in biochemical and cell biology assays
• Determined drug pharmacological parameters such as Ki, off-rate, EC50, IC50, etc.
• MOA and target validation investigations
• Investigation of signaling pathways including MAP signaling and immune signaling
• Worked with both immortal cells and primary cells and isolated cells from tissue
• Developed assays for measuring target engagement (NanoBRET and CETSA), cell biomarkers, intracellular binding rates, biochemical binding affinity, degradation, cytotoxicity, and more

San Diego

• Developed and validated quantitative and qualitative ligand-binding assays through assay experimentation, data analysis, and writing of procedures and reports
• Troubleshooted and corrected a wide variety of issues with immunoassays
• ELISA/ECL/MSD for the purpose of PK, biomarker, and ADA analysis
• Screening of antibodies for binding affinity/specificity through immunoassay testing
• Immuno-precipitation of proteins for trypsin digestion and mass spectrometry fingerprinting for proteomic analysis of serum proteins
• SDS-PAGE and related protein staining techniques and subsequent analysis of protein composition

San Diego

• Prepared reagents, performed extractions, and operated common laboratory equipment
• Utilized automated liquid handling systems
• Reviewed mass spectrometry/liquid chromatography instrument paperwork and results tables
• Communicated sample discrepancies to clients, helped clients resolve discrepancies, and resolved inspection reports
• Utilized excel to manipulate LIMS database and ensure accuracy of database
• Maintained LIMS systems

Vestal, NY

• Worked with team at high pace to handle/pack/distribute various medications to patients/organizations

- Taught college students for biology, chemistry, calculus, and behavioral neuroscience courses- Explained concepts to high school students and assisted them in their math courses- Prepared lesson plans to assist students in their studies and answered any questions

Binghamton University

• Handled rats and put them through their daily tests/experiments
• Post-operative care and checkups
• Rodent injections
• Formulated reagents for experiments and administered to animals
• Tissue processing, sectioning with cryotome, histological analysis such as staining and microscopic analysis
• Analyzed neural data originating from CNS extracellular electrodes

4400 Vestal Pkwy E, Binghamton, NY 13905

• Instructed 20+ students during laboratory sessions and guided them through laboratory procedures
• Created lesson plans for conduct of classes
• Graded homework and quizzes
• Conducted office hours to answer student questions

• Cell and Molecular Biology Lab
• Operated microscopes and examined tissues
• PCR, electrophoresis, molecular biology techniques
• Bacterial cell culture and microbiology techniques
• Analyzed quantitative and quantitative results
• Studied different sequencing methods ranging from sanger sequencing to next generation sequencingGeneral Chemistry and Organic Chemistry Labs

1 Playland Pkwy, Rye, NY 10580

• Provided customer service by communicating with customers and addressing their needs
• Illustrated the various attractions in the park to customers