Christopher Ostrowski Email & Phone Number

Guelph, Ontario, Canada

Determine release eligibility of finished product batches of Veterinary drugs, Veterinary Biologics and Veterinary Pesticides. Investigate and assess deviations. Manage Change Controls from initiation to closure. Lead local vendor management procedure. Review and draft APQR's. Strive to streamline procedures while maintaining compliance. Local approver of product complaints.

Determine eligibility of production batches for release to the Canadian, US and international markets by reviewing production batch records. Review and close investigations for minor deviations. Communicate with other departments such as QC and supply chain to ensure all required testing and documents are completed in time for batch release. Track quality systems for the facility to monitor if target dates are being met. Assist in facility internal GMP audits. Audit electronic systems in QC labs to ensure compliance.

● Prepares and reviews protocols and reports for submission to the Canadian Centre for Veterinary Biologics (CCVB) and the United States Center for Veterinary Biologics (CVB)● Plans and coordinates internal and external animal research trials including field safety trials for product licensure● Prepares required documentation for shipping experimental vaccine to the United States under 9 CFR 103.3● Assembles and formats data for submission to statistics department and CVB● Routinely extracts and titrates Eimeria oocysts and DNA from feces● Uses PCR to determine the presence and absence of specific Eimeria species● Propagates pure cultures of Eimeria spp. by passaging through chickens and turkeys

● Cultured mammalian cells to volumes large enough to inoculate bioreactors● Commissioned 10 L and 100 L bioreactors to grow mammalian cells● Troubleshot equipment on bioreactors when not functioning correctly ● Created SOP’s and batch production records to document procedures used to grow cell seed and grow cells in bioreactors● Part of a team working to develop a method to determine virus titer and vaccine potency for use in routine quality control testing● Reviewed Batch Production Records for accuracy and completeness according to GMP● Revised SOP’s and BPR’s so they were correct and easily followed● Acted as alternate quality control technician, determining sterility of product and concentration of virus● Participated in filling and coating vaccine filled blisters

● One of three microbiologists responsible for isolating and enumerating bacteria and fungi from a wide variety of materials while adhering to standard methodologies and protocols● Identified bacterial isolates using staining and biochemical tests● Analyzed the cleanliness of the facility by conducting air monitoring and contact plates to ensure a contamination-free environment● Evaluated the quality of in-house purified water using membrane filtration and heterotrophic plate counts● Collaborated with the Research and Development division to determine success rates of disinfectants in accordance with AOAC standard methods; presented key findings to Management on a weekly basis ● Edited and updated SOP’s to make them easy to understand and follow● One of six members of the Product Development team; met regularly with the President to strategize ways to develop and implement new products while overcoming any unforeseen obstacles● Supervised lab co-op students and demonstrated laboratory procedures

My project involved in vivo bioluminescence imaging to gain insight into the infection process of the fish pathogen Yersinia ruckeri. An additional part was to discover genetic methods to distinguish between serotypes.● Conducted animal infection experiments including isolation and identification of bacteria.● Examined the feasability of in vivo biolouminescence imagin in rainbow trout. ● Utilized molecular biology tools including but not limited to DNA isolation, PCR and Southern blotting.● Cared for research animals at time of challenge and in general holding.● Developed serotype specific PCR primers for a fish pathogen.● Analyzed lipopolysaccharide by extraction and SDS-PAGE.

Was a graduate teaching assistant for bacteriology, molecular biology and mycology courses for first year and upper level undergraduates.● Supervised and evaluated first year and senior undergraduate laboratory courses.● Evaluated upper level student molecular biology formal reports.● Demonstrated microbiological techniques including bacterial culture maintenance and identification for undergraduate students.

Worked on elucidating the role of mutations that caused attenuation to a pathogenic bacteria.● Examined bacterial samples using light microscopy.● Analyzed bacterial samples using transmission electron microscopy.● Purified and analysed lipopolysaccharide by gel electrophoresis and silver staining.

Master Of Science (M.Sc.), Molecular And Cellular Biology

Bachelor Of Science (Bsc), Microbiolgy