Christopher Shen Email and Phone Number
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Growth phase leader for cell & gene therapy development and commercialization
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Founder & CeoAleutian Therapeutics Jun 2024 - PresentSourced promising technology to treat Type 1 diabetesCompleted HomeLab pre-accelerator program at UCSD
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Co-Founder And Managing DirectorSaber Consulting Llc Apr 2023 - PresentLos Angeles, Us -
Senior Director, Global Manufacturing Sciences And TechnologyInstil Bio Aug 2020 - Apr 2023Led and built global MSAT organization with facilities in both US and UK resulting in two IND approvals for investigational TIL therapies.Solved problems during academic to industry transfer, facility startup, and manufacturing sciences Role expanded to Head of MSAT and Process Development in Dec 2022. Continued to solve problems until I wasn't allowed to solve problems anymore (company ended US operations). -
Director, Manufacturing Sciences And TechnologyKite Pharma Mar 2019 - Aug 2020Santa Monica, California, UsLed and built the site MSAT organization to support startup of a commercial CAR-T manufacturing facility near Amsterdam.Oversaw technology transfer and solved problems resulting in first end-to-end commercial CAR-T manufacturing facility in Europe. -
Senior & Principal Engineer, Process DevelopmentKite Pharma Aug 2014 - Mar 2019Santa Monica, California, Us~30th full-time employee at KiteLed projects and solved problems in process and product development from pre-IND to commercial approval for KTE-C19 (YESCARTA) leading to industry leading >99% clinical manufacturing success rateSolved problems in manufacturing sciences for KTE-X19 (TECARTUS)Led technology transfer of KTE-C19 to Europe and China resulting in first-in-class CAR-T MAA and NDA filings in those geographiesLed comparability studies for site to site tech transfers and process changesLed process validation for Yescarta BLA and MAA filings
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Adjunct ProfessorKeck Graduate Institute Jan 2013 - Dec 2019Claremont, Ca, UsTeach and mentor graduate students in bioprocessing. -
Scientist, FermentationAllergan Jul 2012 - Aug 2014Dublin, Coolock, IeOversaw technical projects in fermentation process development, designing experiments, maintaining knowledge of technical and business developments, analyzing data, and drafting reports and standard operating protocols. Held responsibility for bioreactor engineering, scale-up and media development. - Led design and implementation of first in-house fed-batch platform.- Designed E. coli fed-batch process, generating improvement in cell density by 400% over in-house batch process.- Led project investigating use of disposable bioreactors for microbial fermentation, demonstrating successful process with cell densities and titers comparable to stainless steel systems. -
Postdoctoral FellowKeck Graduate Institute Sep 2011 - Jul 2012Claremont, Ca, UsAdvisor: Matthew CroughanConducted research in process development, working with mammalian cells (CHO), stem cells, E. coli, and Pichia pastoris. Performed bioreactor experiments, cell density measurements, cell viability measurements, and metabolite concentration measurements. Utilized shake flasks and lab scale reactors. Taught courses in upstream and downstream bioprocessing, mentoring masters students. Served as sole instructor for protein purification course, teaching 15 students, organizing curriculum, coordinating guest speakers, and writing and grading exams.- Cultivated extensive experience in lab-scale bioreactor growth and maintenance of mammalian cell culture and microbial fermentation, studying both disposable and reusable systems. - Worked closely with team to test cell density limits for disposable bioreactor technology in CHO process.- Collaborated with team to evaluate feasibility of disposable bioreactor technology for microbial process.- Evaluated effectiveness of cell culture media supplementation on cell growth and productivity. Presented data at international cell culture conference.- Performed bioprocess development for stem cell culture.
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Graduate Research AssistantGeorgia Institute Of Technology And Emory University Aug 2005 - May 2011Advisor: Shuming NieDirected independent research project, adding in novel and important findings to body of scientific knowledge. Worked in bionanotechnology and developed nanoparticles to act as carriers, enabling therapeutic use of new “nucleic acid” class of drugs. Served as teaching assistant for two engineering courses, leading recitation sections, reviewing weekly material with students, and writing homework and exam questions. - Developed quantum dot-antibody conjugates for diagnostic molecular imaging, resulting in peer-reviewed publication. - Performed diagnostic and therapeutic research and development for cancer applications.- Created fluorescent and magnetic in-vitro diagnostic assay for quantifying biomolecules in solution with femtomolar sensitivity, representing 1,000-fold improvement compared to other published methods.- Identified nanoparticle polymer coatings and sizes optimal for intracellular drug delivery of siRNA and other oligonucleotides.
Christopher Shen Skills
Christopher Shen Education Details
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Georgia Institute Of TechnologyJoint Program With Emory University -
Emory UniversityJoint Program With Georgia Tech
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University Of California, BerkeleyBioengineering
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Georgia Tech Scheller College Of BusinessTechnology Entrepreneurship
Frequently Asked Questions about Christopher Shen
What company does Christopher Shen work for?
Christopher Shen works for Aleutian Therapeutics
What is Christopher Shen's role at the current company?
Christopher Shen's current role is Problem Solver | Founder | Cell & Gene Therapy Development.
What is Christopher Shen's email address?
Christopher Shen's email address is cs****@****rma.com
What is Christopher Shen's direct phone number?
Christopher Shen's direct phone number is +131082*****
What schools did Christopher Shen attend?
Christopher Shen attended Georgia Institute Of Technology, Emory University, University Of California, Berkeley, Georgia Tech Scheller College Of Business.
What skills is Christopher Shen known for?
Christopher Shen has skills like Cell Culture, Biotechnology, Fermentation, Protein Purification, Biomedical Engineering, Cell, Stem Cells, Mammalian Cell Culture, Laboratory, Bioprocessing, Microbiology, Assay Development.
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