Chris W. Email and Phone Number
My career path has taken me from scientist and researcher to director-level leader. Deep knowledge and experience in biotechnology and biochemical engineering allow me to manage complex scientific work and diverse multi-disciplinary teams in manufacturing, quality, sales, and R&D to attain operational goals. The work and people in the world of R&D are diverse. I have developed a well-honed skillset that balances emotional intelligence and people skills with technical and scientific expertise. During college, I discovered my love for math and chemistry and became intrigued by how scale and energy easily transferred to biochemistry. When my dad got sick and received an experimental clinical treatment that saved his life, I committed to using my talents in math and biochemistry to help people.One of my most significant achievements was getting the Bovine Gamma Globulin Process completed. I began as the designer of the process and ended up as project leader for product development for a top 3 company in Vitro Diagnostic. A crucial part of my leadership was training the team on the importance of problem-solving through cross-functional collaboration.What makes me an effective leader and scientist and differentiates me from others:• Experience leading diverse areas of clinical research, bioprocessing, and basic mechanisms of action research.• Deep expertise in chemistry and biochemistry process development and scale-up, complex scientific projects and clinical trials, product development, data analytics and reporting, lab operations management, industry publications, and presentations.• Leadership that communicates trust and confidence empowers the team to take initiative and ownership, make smart decisions, and view mistakes as opportunities for learning while providing support. • Working collaboratively to connect concepts, people, and resources to leverage collective knowledge and improve group function.• Ability to make connections between ideas or experiences that initially appear unrelated but actually hold connections that can accelerate the work. • Thoughtful consideration of choices and their implications, anticipation of results, and impact on experimental designs—always beginning and working with the end in mind.• Can switch between thinking strategically and dealing with the minutiae quickly. My ultimate goal is to lead scientific teams with a diversity of projects that make major impacts on the growth of revenues in new or current markets with products that improve people's lives or are in the chain of improving people's lives.
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Vice President Of Research And DevelopmentProliant Health & BiologicalsDes Moines, Ia, Us
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Vice President Of Research & DevelopmentProliant Health & Biologicals Jul 2024 - Present -
Director Of Research DevelopmentProliant Biologicals Feb 2021 - Aug 2024Des Moines County, Iowa, United StatesLead 7 direct reports and oversee cross-functional and multi-disciplinary teams in manufacturing, quality, sales, and research and development in attaining operational goals that align with corporate objectives. Manage and monitor a $1.5M budget. R&D• Spearhead research and product development projects.• Drive innovation and continuous process improvement for maximum efficiency.• Implement policies and procedures to optimize daily operations.• Communicate status… Show more Lead 7 direct reports and oversee cross-functional and multi-disciplinary teams in manufacturing, quality, sales, and research and development in attaining operational goals that align with corporate objectives. Manage and monitor a $1.5M budget. R&D• Spearhead research and product development projects.• Drive innovation and continuous process improvement for maximum efficiency.• Implement policies and procedures to optimize daily operations.• Communicate status, progress reports, and relevant research information to keep executives informed. • Serve as a knowledge resource on biological research to management, sales staff, manufacturing plants, and customers.Leadership & Management• Hire, facilitate training, coach, and mentor employees to strengthen analytical and research skills.• Elevate employee performance to deliver tangible results by setting clear expectations, encouraging creative thinking, and establishing stretch goals that challenge and engage the team. • Promote open communication, idea sharing, and skills training to build bench strength, leverage collective intelligence, and improve group function, processes, and products.• Develop and manage department operational plans, including defining organizational policies, coordinating functions and operations between departments, and establishing actionable strategies for attaining company goals.• Managed and adapted to leadership changes and shifting organization culture and structure after company merger; focused on alignment with strategic goals of One Company and continuous improvement efforts. Show less
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Senior ScientistProliant Biologicals Aug 2018 - Feb 2021Des Moines, Iowa AreaLed 2 direct reports on development of new processes and products. Oversaw multi-functional teams in manufacturing, quality, sales, and R&D.• Led technical transfer and modification of sulfhydryl blocked BSA process from acquisition through bench, pilot, and into manufacturing validation at NZ site hitting all key project deliverables and milestones in six months.• Managed technical customer-based projects including communications and timelines with internal and external partners… Show more Led 2 direct reports on development of new processes and products. Oversaw multi-functional teams in manufacturing, quality, sales, and R&D.• Led technical transfer and modification of sulfhydryl blocked BSA process from acquisition through bench, pilot, and into manufacturing validation at NZ site hitting all key project deliverables and milestones in six months.• Managed technical customer-based projects including communications and timelines with internal and external partners. • Oversaw expectations and deliverables when PHB and external goals were not aligned.• Developed new basic R&D projects to understand how medical food product could interrupt mechanisms of COVID infections and supported the launch of an Entergam COVID trail in Spain.• Developed direct reports to become independent researchers with project management skills via coaching and leadership culminating in presentation of their work at conferences and successful commercialization of their processes to produce new products.• Managed through COVID – leading the group through the shift in organizational culture and behaviors associated with remote work, changing safety rules, and job security. • Demonstrated clear and open communication, teamwork, and respect and served as a role model for the group. Show less
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Scientist IiProliant Biologicals Aug 2014 - Aug 2018Des Moines, Iowa, United StatesLed product characterization to support a potential biologics license application using proteomics. Led and mentored 3 research associates on process development, stability and mechanism of action projects.• Managed the execution of tasks by myself or 3 research associates to hit project milestones such as delivering prototype samples to customers, completion of stability studies on key product attributes, analytics validation and process scale-up.• Managed the use of De Novo… Show more Led product characterization to support a potential biologics license application using proteomics. Led and mentored 3 research associates on process development, stability and mechanism of action projects.• Managed the execution of tasks by myself or 3 research associates to hit project milestones such as delivering prototype samples to customers, completion of stability studies on key product attributes, analytics validation and process scale-up.• Managed the use of De Novo Sequencing and 2-D electrophoresis by CROs to identify and quantify all proteins in a protein isolate medical food and supported the development of immunoassays to quantify lot-to-lot differences in antigen binding• Developed troubleshooting & problem-solving skills of research associates to keep projects on track – developing quality control parameters for analytics, procuring loaning equipment from vendors to bridge gaps in lab capabilities. Show less
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Senior Research AssociateProliant Health & Biologicals Dec 2013 - Aug 2014Des Moines, Iowa AreaProject management and product development of a >98% protein product• Developed and optimized bench scale purification process starting from plasma• Process scale-up focusing on maintaining key process attributes• Pilot trials to make process directly scalable for production• Cost and yield analysis• Capital equipment proposal• Development of quality control analyses and assays• Evaluation of vendors and processing equipment• Management of outside lab… Show more Project management and product development of a >98% protein product• Developed and optimized bench scale purification process starting from plasma• Process scale-up focusing on maintaining key process attributes• Pilot trials to make process directly scalable for production• Cost and yield analysis• Capital equipment proposal• Development of quality control analyses and assays• Evaluation of vendors and processing equipment• Management of outside lab projectsProject support for large Pharmaceutical Customers• Identification of contract labs following ICH guidelines• Management of contract lab projects and quotes• Data analysis and communicationAnalytical support for other companies in the LGI familyScientific support for Clinical TrialsLab skills: FPLC, HPLC, Precipitations, ELISA, Mammalian cell proliferation assays, Functional assays, Scale-up, Pilot scale processing (300 gallon tanks, continuous centrifugation, ultrafiltration) Show less
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Research Associate In The William Ja Lab, Department Of Metabolism And AgingThe Scripps Research Institute Aug 2010 - Mar 2013Jupiter, Fl•Led project management on conceptual design of a novel modular peptide-protein immunotoxins targeting VEGFR2 or FSHR on mammalian cells. • Generated a set of modular VEGFR2 receptor targeting domains via synthesis/purification of therapeutic peptides and peptoids, which were conjugated to hetero-dimerization peptides via optimized click-chemistry.• Generated active immunotoxin-like therapeutic molecules by conjugating VEGFR2 targeting domains and cytotoxic proteins via… Show more •Led project management on conceptual design of a novel modular peptide-protein immunotoxins targeting VEGFR2 or FSHR on mammalian cells. • Generated a set of modular VEGFR2 receptor targeting domains via synthesis/purification of therapeutic peptides and peptoids, which were conjugated to hetero-dimerization peptides via optimized click-chemistry.• Generated active immunotoxin-like therapeutic molecules by conjugating VEGFR2 targeting domains and cytotoxic proteins via -dimerization domains tested in cell-based toxicity assays for specificity and toxicity. Show less -
Graduate Research Assistant In Chemical & Biological EngineeringIowa State University Aug 2003 - Jul 2010Ames, IaDuring my doctoral work I was responsible for independently advancing a characterization and crystallization project on a family of endoglucanases. Based off this project I generated ideas for additional research projects involving structure-function relationships, binding thermodynamics, enzyme kinetics, protein stability, and reaction modeling. Although I ran the majority of the experiments, I was also responsible for managing and integrating eleven undergraduate and Master’s students into my… Show more During my doctoral work I was responsible for independently advancing a characterization and crystallization project on a family of endoglucanases. Based off this project I generated ideas for additional research projects involving structure-function relationships, binding thermodynamics, enzyme kinetics, protein stability, and reaction modeling. Although I ran the majority of the experiments, I was also responsible for managing and integrating eleven undergraduate and Master’s students into my projects leading to publishable data. I led collaborations with groups in the Food Science, Chemistry, and Molecular Biology Departments on published works and helped prepare a successful application for beam-time at the Argonne National Lab synchrotron. I had full access to the X-ray crystallography facility where I set-up my crystallization plates, screened freezing conditions, screen crystals to obtain diffraction data, collected data sets, and modeled structures. I presented my research at the American Institute of Chemical Engineers conference in November 2008. My work during this time led to three published journal articles as primary author and a fourth that has been submitted. Show less -
Technical Services Lab/Regulatory CoordinatorQuest International Flavors & Fragrances (Now The Kerry Group) Aug 2001 - Aug 2003Hoffman Estates, Il• Analysis of SOPs, batch records, and product specifications to determine key variables in product performance• Set up pilot runs at GMP production facility for protein hydrolysates to investigate how processing variables affect product performance in fermentation applications• Cross functional team member supporting QC, Manufacturing, Marketing, Process Development and Regulatory• Initiated analysis of amino & organic acid profiles in multiple lots of protein hydrolysate… Show more • Analysis of SOPs, batch records, and product specifications to determine key variables in product performance• Set up pilot runs at GMP production facility for protein hydrolysates to investigate how processing variables affect product performance in fermentation applications• Cross functional team member supporting QC, Manufacturing, Marketing, Process Development and Regulatory• Initiated analysis of amino & organic acid profiles in multiple lots of protein hydrolysate products• Customer visits to discuss processing variables & product performance (NY, CA)• Regulatory work for US & EU clients. Confidential disclosure agreement coordination Show less
Chris W. Education Details
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Chemical Engineering
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Chemical And Biological Engineering
Frequently Asked Questions about Chris W.
What company does Chris W. work for?
Chris W. works for Proliant Health & Biologicals
What is Chris W.'s role at the current company?
Chris W.'s current role is Vice President of Research and Development.
What schools did Chris W. attend?
Chris W. attended Iowa State University, University Of Iowa.
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Chris Malins
Innovative Finance And Accounting Professional With Extensive Experience In Higher EducationSeattle, Wa5uw.edu, yahoo.com, washington.edu, u.washington.edu, washington.edu3 +120661XXXXX
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Chris Yandow
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