Christopher Davitt, Phd Email & Phone Number

Boston, MA, US

Waltham, MA, US

Waltham, MA, US

Waltham, MA, US

Boston, MA, US

Medford, MA, US

Cambridge, MA, US

- Established and led in-house bio-distribution, PK/PD and mechanistic studies in rodent models- Managed research associates and external research partnerships (academic, industry and CRO)- Contributed T and NK cell MOA data to manuscript for lead oncology candidate

Cambridge, MA, US

- Performed due diligence on a novel formulation technology, championed adoption, drove development as a leading clinical asset- Executed key pre-clinical PK/PD and efficacy studies to evaluate and progress novel drug-derivatives into clinical development- Collaborated with IP team to generate data and describe scientific rationale for patent filings.

New Orleans, LA, US

- Developed ex vivo T cell restimulation and serum-antibody ELISA assays to measure and establish immune-correlates or protection against a novel outer membrane vesicle vaccine against Burkholderia pseudomallei in mice and non-human primates- Optimized in vitro and vivo readouts of murine dendritic cell activation with OMVs- Demonstrated the synergy of.

- Developed the immune-assay component of a prototype device together with bio-medical engineers- Contributed significant data to patent filing- Presented elevator pitch deck at business competitions- Worked as part of a team to identify, due diligence and pursue diagnostic opportunities against human and agricultural infectious disease

Dublin, IE

- Optimized, evaluated and selected a final candidate Helicobacter Pylori oral vaccine formulation using readouts of cellular and humoral immunity in the mucosal and systemic compartments- Performed toxicology studies on prototype oral vaccine- Elucidated a novel role for the IL-1 and IL-17 receptors in the adjuvant response to alpha-galcer- Work was.

Dublin, IE

- Adapted the SmPill drug delivery system (Sigmoid Pharma) into an oral vaccine delivery vehicle- Demonstrated enhanced mucosal S-IgA and systemic IgG responses against a novel enterotoxogenic E.coli and Cholera oral vaccine candidate utilizing the SmPill- Identified a possible role for the IL-17R as a novel bio-marker as an indicator of oral vaccine.

Dublin, IE

- Provided extracurricular tutoring to disabled students in Biochemistry, Biology and Immunology- Assisted science students with practical lab work

Dublin, IE

- Taught the application of practical biochemical, molecular, cellular and immunological techniques and concepts to Undergraduate Students from courses including Natural Science (1st, 2nd, 3rd Years), Medicine and Immunology and Master's Students in Immunology.

Dublin, IE

- Demonstrated the selective targeted enhancement of polystyrene particle uptake by dendritic cells with plant lectins leading to increased dendritic cell activation in vitro- Showed an increase in T cell response after vaccination with lectin targeted polystyrene particles in vivo- Work contributed to patent filing

La Jolla, CA, US

- Independently organized work experience placement in the summer of 2009 in the lab of Dr. Donald Newmeyer- Helped manage the lab’s mouse colony including setting up breeding pairs, weaning, geno- and phenotyping litters- Assisted in bacterial transfection, plasmid production, protein expression and general lab management

Doctor Of Philosophy (Ph.D.), Oral Vaccination, Enteric Diseases And Mucosal Immunology

Professional Diploma (Awarded By Institute Of Commercial Management), International Business Studies

Ba Mod, Hons., Biochemistry And Immunology

Leaving Certificate