Christopher Davitt, Phd Email and Phone Number
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Proven R&D track record of success in multifaceted pre-clinical and early stage drug discovery as demonstrated by the development of 4 vaccine candidates as well as novel formulations of existing drug candidates and advancement of next generation drug modalities into candidate selection and clinical programs.Creative and critical thinker skilled in Immunological Research with excellent written communication skills (6 publications, 2 grants and 6 patents). Strong oral communication skills developed through presentation of data at prestigious national and international conference and winning a national science communication competition. Dynamic contributor to team efforts as demonstrated by numerous successful international academic and industry collaborations and inter-disciplinary R&D projects.Entrepreneurial and innovative spirit with a history of securing inventorships, driving new candidate selection and adoption of new pre-clinical technologies while working at a thriving biotech startup. Success in fundraising for graduate and postdoctoral research, pitch development for business competitions, and development of a prototype device for point of care diagnostics.
Bostongene
View- Website:
- bostongene.com
- Employees:
- 387
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Business Development And Alliance ManagerBostongeneBoston, Ma, Us
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Associate Director, Business Development And Alliance ManagementBostongene Sep 2023 - PresentWaltham, Ma, Us
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Business Development And Alliance ManagerBostongene Jan 2023 - Sep 2023Waltham, Ma, Us
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Program Alliance ManagerBostongene Jan 2022 - Jan 2023Waltham, Ma, Us
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Principal ScientistDeepcure Jul 2021 - Jan 2022Boston, Ma, Us -
Senior Scientist, ImmunologyGreenlight Biosciences, Inc. Jul 2020 - Jul 2021Medford, Ma, Us -
Senior Scientist, Innovation And TechnologyEvelo Biosciences Jan 2020 - Apr 2020Cambridge, Ma, Us- Established and led in-house bio-distribution, PK/PD and mechanistic studies in rodent models- Managed research associates and external research partnerships (academic, industry and CRO)- Contributed T and NK cell MOA data to manuscript for lead oncology candidate -
Scientist, Innovation And TechnologyEvelo Biosciences Jul 2017 - Dec 2019Cambridge, Ma, Us- Performed due diligence on a novel formulation technology, championed adoption, drove development as a leading clinical asset- Executed key pre-clinical PK/PD and efficacy studies to evaluate and progress novel drug-derivatives into clinical development- Collaborated with IP team to generate data and describe scientific rationale for patent filings- Optimized and led adoption of assays to measure immune cell activation in the tumor micro-environment - Authored and reviewed non-clinical reports and contributed key data towards clinical trial design- Introduced and optimized T cell and knockout mouse MOA studies on lead anti-inflammatory candidates
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Postdoctoral Research FellowTulane University Jan 2015 - Jul 2017New Orleans, La, Us- Developed ex vivo T cell restimulation and serum-antibody ELISA assays to measure and establish immune-correlates or protection against a novel outer membrane vesicle vaccine against Burkholderia pseudomallei in mice and non-human primates- Optimized in vitro and vivo readouts of murine dendritic cell activation with OMVs- Demonstrated the synergy of TLR-4, NLRP3 inflammasome and caspase 11 sensing pathways by dendritic cells after OMV stimulation- Identified a role for caspase-11 in the development of T cell responses against OMVs- Pursued a novel avenue to filed a patent for OMV-based vaccines in a crowded intellectual property landscape- Mentored PhD students in lab and lectured three graduate level courses- Wrote and was awarded a research grant, ad hoc reviewer for peer-reviewed journals- Presented work at local, national and international conferences and published a manuscript -
Scientific Research ConsultantFlux Diagnostics May 2015 - Jan 2016- Developed the immune-assay component of a prototype device together with bio-medical engineers- Contributed significant data to patent filing- Presented elevator pitch deck at business competitions- Worked as part of a team to identify, due diligence and pursue diagnostic opportunities against human and agricultural infectious disease -
Postdoctoral ResearcherTrinity College Dublin Mar 2014 - Dec 2014Dublin, Ie- Optimized, evaluated and selected a final candidate Helicobacter Pylori oral vaccine formulation using readouts of cellular and humoral immunity in the mucosal and systemic compartments- Performed toxicology studies on prototype oral vaccine- Elucidated a novel role for the IL-1 and IL-17 receptors in the adjuvant response to alpha-galcer- Work was conducted as part of a European Union (EU) funded consortium between international research groups and industry collaborators (HELICOVAXOR) requiring regular meetings, presentation of data and report writing for multi-disciplinary audience- Contributed data to patent filing, reports to funding agency and published a manuscript -
Graduate Student ResearcherTrinity College Dublin Sep 2010 - Mar 2014Dublin, Ie- Adapted the SmPill drug delivery system (Sigmoid Pharma) into an oral vaccine delivery vehicle- Demonstrated enhanced mucosal S-IgA and systemic IgG responses against a novel enterotoxogenic E.coli and Cholera oral vaccine candidate utilizing the SmPill- Identified a possible role for the IL-17R as a novel bio-marker as an indicator of oral vaccine efficacy against S-IgA mediated infections- Collaborated with an external research group to evaluate a novel subcutaneous tetanus toxoid vaccine and adapting it to oral administration- Prepared and published 2 research papers and 2 review articles- Mentored undergraduate research students and PhD candidates- Regularly wrote reports for industry partner, presented data at lab meetings, multi-disciplinary meetings with collaborators, presented a poster at an international conference and contributed data to patent filing
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Educational Support WorkerTrinity College Dublin Dec 2011 - Dec 2013Dublin, Ie- Provided extracurricular tutoring to disabled students in Biochemistry, Biology and Immunology- Assisted science students with practical lab work
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Graduate Teaching AssistantTrinity College Dublin Oct 2010 - Dec 2013Dublin, Ie- Taught the application of practical biochemical, molecular, cellular and immunological techniques and concepts to Undergraduate Students from courses including Natural Science (1st, 2nd, 3rd Years), Medicine and Immunology and Master's Students in Immunology.
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Undergraduate Student ResearcherTrinity College Dublin Nov 2009 - Mar 2010Dublin, Ie- Demonstrated the selective targeted enhancement of polystyrene particle uptake by dendritic cells with plant lectins leading to increased dendritic cell activation in vitro- Showed an increase in T cell response after vaccination with lectin targeted polystyrene particles in vivo- Work contributed to patent filing
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Research AssistantLa Jolla Institute For Allergy And Immunology May 2009 - Sep 2009La Jolla, Ca, Us- Independently organized work experience placement in the summer of 2009 in the lab of Dr. Donald Newmeyer- Helped manage the lab’s mouse colony including setting up breeding pairs, weaning, geno- and phenotyping litters- Assisted in bacterial transfection, plasmid production, protein expression and general lab management
Christopher Davitt, Phd Skills
Christopher Davitt, Phd Education Details
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Trinity College DublinEnteric Diseases And Mucosal Immunology -
Dublin Business SchoolInternational Business Studies
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Trinity College DublinBiochemistry And Immunology
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Mount Temple Comprehensive SchoolLeaving Certificate
Frequently Asked Questions about Christopher Davitt, Phd
What company does Christopher Davitt, Phd work for?
Christopher Davitt, Phd works for Bostongene
What is Christopher Davitt, Phd's role at the current company?
Christopher Davitt, Phd's current role is Business Development and Alliance Manager.
What is Christopher Davitt, Phd's email address?
Christopher Davitt, Phd's email address is cd****@****ane.edu
What is Christopher Davitt, Phd's direct phone number?
Christopher Davitt, Phd's direct phone number is +150498*****
What schools did Christopher Davitt, Phd attend?
Christopher Davitt, Phd attended Trinity College Dublin, Dublin Business School, Trinity College Dublin, Mount Temple Comprehensive School.
What are some of Christopher Davitt, Phd's interests?
Christopher Davitt, Phd has interest in Cooking, Cars And Motorbikes, Reading, Fitness, Music, Craft Beer.
What skills is Christopher Davitt, Phd known for?
Christopher Davitt, Phd has skills like Cell Culture, Immunology, Vaccines, Science, Flow Cytometry, In Vivo, Mucosal Immunology, Elisa, Cell Biology, Adjuvants, Academic Tutoring, Microsoft Office.
Who are Christopher Davitt, Phd's colleagues?
Christopher Davitt, Phd's colleagues are Francesca Paradiso, Dmitrii Snitkin, Ani Aloyan, Natalia Khotkina, Grace Goyette, Basim Salem, Varuzhan Jhangiryan.
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