Christy Lanson Email & Phone Number

Ireland

• Conduct a range of standard microbiological analytical techniques, which include, but are not limited to, environmental monitoring, sampling and testing of WFI, growth promotion testing, TOC and conductivity testing, in-process product testing, and final product testing in accordance with GMP standards. • Carry out supportive tasks to ensure overall lab readiness, qualification of laboratory equipment, and validation of methods.• Document experimental procedures and results in Electronic Laboratory Notebook (ELN).• Adhere to current analytical practices as outlined in pharmacopoeias, specifications, regulations, and industry standards.• Ensure proper housekeeping and Good Laboratory Practices (GLP) are upheld in the laboratory.• Calibrate and upkeep all assigned laboratory instruments.• Participate and adhere to the requirements of the Quality Management System.• Engage in risk assessments, inspections, audits, and incident investigations, and carry out and monitor corrective and preventive actions.• Ensure training is current for all job functions performed and assist in onboarding new analysts on routine procedures and practices.• Investigate and identify the root causes of Out of Specification and Out of Trend results.• Receive and manage the samples that arrive at the lab for testing.• Accountable for fostering a culture of Continuous Improvement.• Encourage and engage in the implementation and upkeep of the appropriate safety programs.• Ensure data integrity and adherence to company SOPs, specifications, and current Good Manufacturing Practices (cGMP) regulations.

• Performing routine and non-routine analysis in GMP environment as requested by the Group Leader and Customer representative.• Effectively testing pH and conductivity of water samples.• Accurately performing the calibration and use of laboratory instrumentation• Environmental Monitoring of ISO 5, ISO 6, ISO 7 and ISO 8 cleanrooms and isolators.• Participating in all training required and scheduled in the Compliance Wire.• Ensuring the development of SOPs and protocols in collaboration with the customer.• Performing scientific procedures and produce accurate results within the time frame under the customer Quality system.• Conducting the quality analysis in accordance with ALCOA principle.• Liaising with departments like Quality Assurance, Quality control, R&D, Marketing, Manufacturing, Analytical testing, Microbiology Analysis, Validation and Warehouse. • Preparing samples for environmental monitoring of viable air and non-viable air by settle plate method, contact surface method and SAS air sampler in an aseptic cleanroom.• Collecting the samples for Quality check within Biological Safety Cabinet.• Incubating and counting colony forming units of environmental monitoring plates.• Participating in regulatory agency inspections, audits and interacting with inspectors.• Effectively trained for stage 5 Gowning for working in the GMP environment.• Collecting Water for Injection samples and gas samples for environmental quality check.• Contemporaneously documenting the samples collected in logbooks, LIMS and Nautilus.

Ireland

• Performed production of pharmaceuticals in a GMP set up using manual and automated machines in line with standard operating procedures (SOP).• Performed routine Quality Control testing including finished product analysis to ensure continuous process improvement.• Planned and implemented procedures for mixing, filtration, packaging, and labelling pharmaceuticals, according to policy and legal requirements. • Performed inventory control, completion of traceability documentation, stock entry and ordered the materials from other pharmaceutical companies.• Actively performed sterilization of medical devices and equipment required for manufacturing of pharmaceuticals.• Liaised with departments like Quality Assurance, Quality control, R&D, Marketing, Manufacturing, Analytical testing, Microbiology Analysis, Validation, and Warehouse.

Dublin, County Dublin, Ireland

• Performed the expression of recombinant protein 6-His-mCherry-EF2 in Escherichia coli BL21 expression system.• The expression level of 6-His-mCherry-EF2 was optimised by optimising the concentration of Isopropyl β-D-1-thiogalactopyranoside (IPTG) the inducer, temperature and the induction time.• Analysed the expression level of recombinant protein by Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE) technology.• Performed Immobilised Metal Affinity Chromatography (IMAC), and Size Exclusion Chromatography (SEC) on Fast Protein Liquid Chromatography (FPLC) for purification of recombinant protein with a Sephadex G 200 column.• The concentration of the purified protein was determined by Nanodrop technology.• Performed three rounds of Phage Display Technology on immuntubes to collect the mixture of phages that bound to the antigen. • Performed Enzyme Linked Immunosorbent Assay (ELISA) to identify the specific monoclonal antibodies against purified 6His-mCherry-EF2 protein.• Analysed affinity selection and affinity screening by using Tomlinson J library.• Defined and characterised the antigen-antibody interaction, receptor and antigen-binding sites. • Performed sequencing of monoclonal antibodies by joining with Eurofins Genomics.• Analysed the Single-chain fragment variable (scFv) to characterise the unique binders from monoclonal phage ELISA.• Compared the translations in the sequences by multiple sequence alignment program, CLUSTAL-Omega in FASTA format.• Performed Cross reactivity test to check whether the antibody binds with other similar antigens like Bovine Serum Albumin (BSA) Green Fluorescent protein (GFP)- EF2, GFP-EF1.• Performed Good Laboratory Practice by ensuring deep cleaning of bacterial culture and phage display with bleach.• Conducted Bradford protein assay to measure the concentration of total protein in a sample by measuring the Optical Density in spectrophotometer.

• Manufactured medications prescribed by doctors and dentists by calculating, weighing, measuring, and mixing ingredients in accordance with current Good Manufacturing Practices and under Standard Operating Procedures.• Dispensed up to 1000 prescriptions daily with 100% accuracy, managed, and improved the overall performance of the Pharmacy. • Planned and implemented procedures for mixing, packaging, and labelling pharmaceuticals, according to policy and legal requirements, to ensure quality, security, and effectiveness. • Advised patients and health care professionals about the rational use of drugs. Maintained high morale, integrity, respect, and a positive atmosphere.

Master Of Science - Ms, Biotherapeutics

Activities and Societies: Antibody discovery, Target Binding, ELISA, Western Blotting, Phage Display Technology, DNA Sequencing, PCR.

Bachelor'S Degree, Pharmacy

Have acquired knowledge in areas such as Organic Chemistry, Inorganic Chemistry, Pharmacognosy, Pharmaceutical Sciences, Medicinal.

Hsc, 98.6%

Ssc, Cgpa 10