Charles Lin

Charles Lin Email and Phone Number

Senior Software Engineer @ Cold Start Therapeutics
San Diego, CA 92126, US
Charles Lin's Location
Seattle, Washington, United States, United States
Charles Lin's Contact Details

Charles Lin work email

Charles Lin personal email

n/a
About Charles Lin

Publication History: https://scholar.google.com/citations?user=ktNJ_UUAAAAJ&hl=enWhat my friend thinks I do: "So he just writes computer programs to try out drugs virtually. They just throw thousands upon thousands of drug ideas at the computer, and then it like simulates all the chemical reactions as best it can, and then it gives like a confidence value out that's like this drug might work or this drug doesn't work."What my parents think I do: "Writes code for supercomputers" What I think I do: “Sit in my chair for 5 minutes then write a line of code. Rinse and repeat.”

Charles Lin's Current Company Details
Cold Start Therapeutics

Cold Start Therapeutics

View
Senior Software Engineer
San Diego, CA 92126, US
Website:
coldstart-tx.com
Employees:
5
Charles Lin Work Experience Details
  • Cold Start Therapeutics
    Senior Software Engineer
    Cold Start Therapeutics Aug 2024 - Present
    Formerly known as Athae Bio
  • Tandemai
    Senior Software Engineer Ii
    Tandemai Oct 2022 - Jun 2024
    Designed and implemented end to end workflow for peptide binding and parameterization to support complex small peptides (cyclic, crosslinked, non standard backbones, etc)Implemented more accurate fragmentation schemes for faster & more accurate quantum calculationsWorked on several approaches to increase speed in GPU codes (from hardware level to low level kernel codes)Increased stability of code base by fixing underlying causes of client issuesImplemented methodology to increase accuracy of small molecule binding free energy calculations
  • Self-Employed
    Consultant
    Self-Employed Jul 2016 - Jun 2024
    Wrote efficient GPU-accelerated parallel algorithms for Dart Neurosciences to boost Poisson-Boltzmann calculations (2016-2017)HPC Consultant for a VA Hospital (2021)Grant writer to a small startup (TocsTech) for an EPA SBIR grant (2021)Worked on a pandemic project (CTRL+V), a no-code NFT generator that could also deploy on several chains, which became a grant recipient (2021-2022)
  • Roivant Sciences
    Senior Investigator
    Roivant Sciences Mar 2021 - Aug 2022
    New York, New York, Us
    Helped improve processes by up to 60% in computational screening throughput Helped improve accuracy of assessing binding properties by up to 20%Created novel visualization tools to accurately assess hotspots for compound during lead optimizationFixed fault tolerance in code bases to decrease failure rates by 99% by identifying and fixing crucial bugs
  • Silicon Therapeutics
    Senior Investigator
    Silicon Therapeutics Jan 2020 - Mar 2021
    Same as previous title.Also explored using machine learning methods to accurately predict small molecules binding properties by utilizing voxel-based CNN calculationsDeveloped, implemented, and created a front end (via pymol) for energy decomposition, a novel tool to assess individual free energy of atoms in a molecular binding orientation.
  • Silicon Therapeutics
    Investigator
    Silicon Therapeutics Sep 2018 - Jan 2020
    Develop, implement, and optimize algorithms for drug discovery on CPU+GPUsMove Molecular Dynamics to next generation hardwares (FPGAs + newer CPU/GPU architectures)Develop and implement workflows that help drive drug discovery projectsImplemented and expanded on methodology to increase prediction of ligand binding off ratesCreate novel methodology and visualization tools to accurately assess small molecule properties
  • Glaxosmithkline Pharma Gmbh
    Intern / Graduate Student
    Glaxosmithkline Pharma Gmbh Apr 2017 - Aug 2018
    Brentford, Middlesex, Gb
    Software development for high performance computing machines (GPU boxes, supercomputers, etc)Novel methodologies (Free energy calculations, protein binding, small molecule permeability)Software optimizations1.) Work with Intel on CPU optimizations towards high/mid bin Intel Xeon/Xeon Phi processors for single and multi-thread (http://ambermd.org/intel/index.htm)2.) Work on GPU acceleration (CUDA & a bit of ROCm)
  • San Diego Supercomputer Center
    Graduate Research Assistant - Programmer
    San Diego Supercomputer Center Jan 2015 - Mar 2017
    La Jolla, California, Us
    Code optimizationMethods DevelopmentBiomolecular Software DevelopmentAnalysis of molecular systemsIT Administration for Walker Lab

Charles Lin Education Details

  • University Of California, San Diego
    University Of California, San Diego
    Chemistry
  • The Ohio State University
    The Ohio State University
    Pharmaceutical Sciences

Frequently Asked Questions about Charles Lin

What company does Charles Lin work for?

Charles Lin works for Cold Start Therapeutics

What is Charles Lin's role at the current company?

Charles Lin's current role is Senior Software Engineer.

What is Charles Lin's email address?

Charles Lin's email address is ch****@****mai.com

What schools did Charles Lin attend?

Charles Lin attended University Of California, San Diego, The Ohio State University.

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