Charles Lin Email and Phone Number
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Publication History: https://scholar.google.com/citations?user=ktNJ_UUAAAAJ&hl=enWhat my friend thinks I do: "So he just writes computer programs to try out drugs virtually. They just throw thousands upon thousands of drug ideas at the computer, and then it like simulates all the chemical reactions as best it can, and then it gives like a confidence value out that's like this drug might work or this drug doesn't work."What my parents think I do: "Writes code for supercomputers" What I think I do: “Sit in my chair for 5 minutes then write a line of code. Rinse and repeat.”
Cold Start Therapeutics
View- Website:
- coldstart-tx.com
- Employees:
- 5
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Senior Software EngineerCold Start Therapeutics Aug 2024 - PresentFormerly known as Athae Bio -
Senior Software Engineer IiTandemai Oct 2022 - Jun 2024Designed and implemented end to end workflow for peptide binding and parameterization to support complex small peptides (cyclic, crosslinked, non standard backbones, etc)Implemented more accurate fragmentation schemes for faster & more accurate quantum calculationsWorked on several approaches to increase speed in GPU codes (from hardware level to low level kernel codes)Increased stability of code base by fixing underlying causes of client issuesImplemented methodology to increase accuracy of small molecule binding free energy calculations -
ConsultantSelf-Employed Jul 2016 - Jun 2024Wrote efficient GPU-accelerated parallel algorithms for Dart Neurosciences to boost Poisson-Boltzmann calculations (2016-2017)HPC Consultant for a VA Hospital (2021)Grant writer to a small startup (TocsTech) for an EPA SBIR grant (2021)Worked on a pandemic project (CTRL+V), a no-code NFT generator that could also deploy on several chains, which became a grant recipient (2021-2022)
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Senior InvestigatorRoivant Sciences Mar 2021 - Aug 2022New York, New York, UsHelped improve processes by up to 60% in computational screening throughput Helped improve accuracy of assessing binding properties by up to 20%Created novel visualization tools to accurately assess hotspots for compound during lead optimizationFixed fault tolerance in code bases to decrease failure rates by 99% by identifying and fixing crucial bugs -
Senior InvestigatorSilicon Therapeutics Jan 2020 - Mar 2021Same as previous title.Also explored using machine learning methods to accurately predict small molecules binding properties by utilizing voxel-based CNN calculationsDeveloped, implemented, and created a front end (via pymol) for energy decomposition, a novel tool to assess individual free energy of atoms in a molecular binding orientation.
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InvestigatorSilicon Therapeutics Sep 2018 - Jan 2020Develop, implement, and optimize algorithms for drug discovery on CPU+GPUsMove Molecular Dynamics to next generation hardwares (FPGAs + newer CPU/GPU architectures)Develop and implement workflows that help drive drug discovery projectsImplemented and expanded on methodology to increase prediction of ligand binding off ratesCreate novel methodology and visualization tools to accurately assess small molecule properties
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Intern / Graduate StudentGlaxosmithkline Pharma Gmbh Apr 2017 - Aug 2018Brentford, Middlesex, GbSoftware development for high performance computing machines (GPU boxes, supercomputers, etc)Novel methodologies (Free energy calculations, protein binding, small molecule permeability)Software optimizations1.) Work with Intel on CPU optimizations towards high/mid bin Intel Xeon/Xeon Phi processors for single and multi-thread (http://ambermd.org/intel/index.htm)2.) Work on GPU acceleration (CUDA & a bit of ROCm) -
Graduate Research Assistant - ProgrammerSan Diego Supercomputer Center Jan 2015 - Mar 2017La Jolla, California, UsCode optimizationMethods DevelopmentBiomolecular Software DevelopmentAnalysis of molecular systemsIT Administration for Walker Lab
Charles Lin Education Details
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University Of California, San DiegoChemistry -
The Ohio State UniversityPharmaceutical Sciences
Frequently Asked Questions about Charles Lin
What company does Charles Lin work for?
Charles Lin works for Cold Start Therapeutics
What is Charles Lin's role at the current company?
Charles Lin's current role is Senior Software Engineer.
What is Charles Lin's email address?
Charles Lin's email address is ch****@****mai.com
What schools did Charles Lin attend?
Charles Lin attended University Of California, San Diego, The Ohio State University.
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