Christian Anthony Chua Email & Phone Number

Berlin, Germany

- Predicted Amazon GMV through Facebook Prophet- Examined the impact of several features changes via A/B tests.

Berlin, Germany

- Simulated different CPO/CPC models for negotiations with the Key Accounts, like Amazon and eBay, that constitute to over a third of idealo’s revenue stream.- Identified hidden inventory trends at specific dimensions including price segment, industry, and dealer-specific fields and inferred the projected growth.- Predicted the impact on shop performance from targeted campaigns, the controlling of inventory through rulesets, and the identification and removal of low-performing or fraudulent offers and merchants.

Berlin, Germany

- Independently developed a pipeline with custom python scripts to study the integration pattern of Sleeping Beauty, a synthetic mobile DNA element, and characterize its safety as a vector in gene therapy.- Employed a Hidden Markov Model to identify patterns of Sleeping Beauty integrations coincident with histone marks, lamina-associated domains, topologically associated domains, and the like.

- Analyzed in R Markdown 10X Genomics single-cell RNA-seq data of young mouse olfactory sensory neurons to illuminate the critical period that the neural network can be repaired after damage.- Employed unsupervised machine learning in Seurat to cluster cells into biologically meaningful groups that accounted for batch effect and mitochondrial contamination.- Produced a robust differential gene expression and cell trajectory analysis complete with visualizations of GO terms and KEGG pathways with fellow bioinformatics peers.

Aliso Viejo, California, United States

- Efficiently delivered several crucial validations for pharmaceutical and regulatory expansions (e.g. FDA) including a circulating tumor DNA NGS assay, the detection of homozygous deletions in homologous recombination repair pathway genes, and the incorporation of the Illumina NovaSeq 6000.

Aliso Viejo, California, United States

- Improved the quality of microarray data by updating the logic for sample-reference pairing in the automated workflow, including a normalization step after purification, and refining analysis settings in NxClinical to be more sensitive.- Implemented a selective hybridization process in the microarray workflow that reduced cost of goods sold by several tens of thousands of dollars.

Aliso Viejo, California, United States

- Rotated through several teams performing multiplex ligation-dependent probe amplification, comparative genomic hybridization, targeted next-generation sequencing, and patient identification through mass spectrometry.

Aliso Viejo, California, United States

- Enhanced the oncology panel with the verification of Sanger and MLPA probes for deep intronic variants, a new APC isoform, and genes associated with brain tumors.

Aliso Viejo, California, United States

- Methodically validated PCR primers, deletion/duplication probes, and NGS libraries of over 200 genes for a neurology panel to CAP/CLIA specifications.- Assisted with the curation, consolidation, and the destruction of over 11,000 specimens following regulatory guidelines (including NY) for AmbryShare, the largest publicly available germline exome data set on hereditary breast and ovarian cancer.

Aliso Viejo, California, United States

- Explored the feasibility of reduced volume reactions, enzymatic shearing, and 192 indexes for the development of a higher throughput and more automated NGS assay.- Validated Sanger primers, MLPA probes, and NGS libraries for a cardiology panel according to CAP/CLIA guidelines.

Los Angeles

- Measured the deformations of A. thaliana nuclei with mutant nuclear lamina in a microfluidic channel under various pressures, a feature that is important for proper expression of mechanosensitive genes.- Self-managed time between cultivating A. thaliana strains, isolating nuclei using nitrous oxide pressurization, and performing quality control with immunofluorescence microscopy.

Los Angeles, California, United States

- Researched the intersection of gender identity, sexual orientation, and ethnocultural background.- Assisted the Program Director with planning and coordinating various LGBTQIA+ events and programs.

- Researched the wave patterns and performance of various wires in series.- Constructed Caltech-designed AC-DC power converter and transformers.

Bachelor Of Science - Bs, Biophysics

Master Of Science - Ms, Bioinformatics And Genomics

Associate Of Arts - Aa, Spanish